Termikon

Description overdue on 10/10/2014

• Latin name: Termicon
• ATC code: D01AE15
• Active substance: Terbinafine (Terbinafine)
• Manufacturer: OAO Pharmstandard, Russia.

Photos of the drug

Tweet

• Composition
• Product form
• Pharmacological action
• Pharmacodynamics and pharmacokinetics
• Indications
• Contraindications
• Side effects
• Instructions for use Termikona (method and dosage)
• Overdose
• Cooperation
• Terms of sale
• Storage conditions
• Shelf life
• Analogs
• With alcohol
• Reviews
• Price, where to buy

Composition

Pills   Termikon contain the active ingredient - terbinafine.

Valium Valium, sodium starch glycolate, lactose, MCC, magnesium stearate, aerosil.

Spray   Termikon includes in its membership:   terbinafine hydrochloride .

Excipients: Proxanol 268, ethanol, propylene glycol, water prepared.

AT cream   contains terbinafine hydrochloride .

Excipients: sodium hydroxide, fenilkarbinol, cetyl, octadecyl alcohol, sorbitan monostearate, ref, isopropyl myristate, polysorbate 60, water prepared.

Product form

The product is available in several forms: pills - 7, 14 and 28 pieces per pack, Spray (15th and 30th c.) And cream (15 oz.).

Pharmacological action

Termikon has fungistatic, fungicidal   and antifungal   action.

Pharmacodynamics and pharmacokinetics

Terbinafine   It affects the processes of fungal cells causing inhibition of squalene epoxidase, which is a fungal enzyme that promotes the synthesis of ergosterol . This leads to a loss of enzyme activity suppression of the synthesis of the basic substance of fungal cell membranes. The action is aimed at Termikona susceptible to the microorganism fungicide, since it is characterized by a wide range of anti-fungal effect. The sensitivity to this drug is: Epidermophyton floccosum, is the causative agent athlete , Microsporum canis, known pathogen mikospor , Trichophyton spp., Trichophyton exciting and dermatophytes . Aspergillus, skopulariopsisy, candida, kladosporiumy   and pathogen pink lichen .

Indications

The drug is in the form of tablets prescribed only in severe cases, or when previous therapy with external agents proved ineffective.

Tablets are recommended for the treatment of:

• Trihofitii;
• jock itch;
• microsporia;
• onychomycosis;
• candidiasis   skin and mucous membranes;
• dermatomycoses   skin with a complicated course.

Indications for the use of cream and spray are:

• tinea pedis;
• multicolored shingles;
• jock itch   light forms;
• fungal skin smooth and certain parts of the body;
• the risk of infection by some fungi - for prevention.

Contraindications

Not recommended for use when Termikon:

• lactation, pregnancy;
• fungal infections in children less than 3 years, up to 20 kg;
• sensitivity to the drug.

During treatment, care should be taken in patients with:

• hepatic insufficiency;
• alcoholism;
• renal insufficiency;
• tumors;
• pathologies of the bone marrow, oppressive blood;
• metabolic disorders;
• disease with occlusion of the vessels of the extremities.

Side effects

When treating Termikonom such deviations can occur, such as: anorexia, agranulocytosis, dyspepsia, myalgia, diarrhea, arthralgia, nausea, rash, stomach pain, thrombocytopenia, rash, change in taste . Lyell's syndrome, neutropenia, cholestatic jaundice   and other.

Instructions for use Termikona (method and dosage)

As the instructions for use of tablets, unit dosages can be at half or a whole tablet, which is taken once a day. Treatment can last for 1-12 weeks. Take the medicine recommended after a meal.

The duration of treatment depends on the disorder, for example, in interdigital tinea   it can reach 4-6 weeks plantar tinea   - 2 weeks; avium head   - 4 weeks, and so forth.

Cream and spray are for external use only. These tools can also be applied to the affected area and the surrounding tissue. Ointment distribute a thin layer and gently rub. Spray previously sprayed and then lightly rubbed. The outer shapes are recommended for use every day for 1-2 times. Before use, the skin is well dried and cleaned. The course of treatment is 4 weeks. On average, the treatment of ringworm   trunk or lower leg,   multi-colored lichen, ringworm   the stop is carried out within 7 days.

Overdose

In cases of overdose Termikonom may occur: nausea, cramps . dizziness, epigastric pain . This symptomatic therapy.

Cooperation

Concomitant use can slow Termikona the metabolism of desipramine, a tricyclic antidepressant structures, fluvoxamine, metoprolol, propafenone, flecainide, propranolol, chlorpromazine   and haloperidol Reduce clearance terbinafine . MAO inhibitors increase the elimination terbinafine .

Suppression biotransformation terbinafine   and increasing its plasma concentrations observed in combination with histamine receptor antagonists . Combination with rifampicin   2 times faster excretion terbinafine , a cimetidine Conversely, slowing down.

Concomitant use with Termikona oral contraceptives   often causes disturbances menstrual cycle . Combination with hepatotoxic drugs   enhances mutual toxicity directed at the activities and the state of the liver.

Terms of sale

Drugs prescription.

Storage conditions

For storage Termikona designed dark place, well protected from children, at temperatures up to 30 C.

Shelf life

2 years.

Analogs

Match code ATC 4th level:

• Fungoterbin
• Mikoseptin
• Soultz
• Nitrofungin
• Baziron AU
• Lamitel
• Exoderil
• Naftin
• Loceryl
• Batrafen
• Terbizil
• Lamisil

In pharmacology, there are many analogs of this drug, such as Ekziter, Lamisil Uno, terbinafine hydrochloride, Lamisil, Binafin, Atrifin, Lamikon , Mikoterbin, Onihon, Mikonorm, Tebikur, Terbiks, Terbinafine Pfizer, Terbizil, Terbinoks, Tsidokan, Tiga-sanovel, Fungoterbin, Lamiter, Terbifin, Mikoter, Lamifast and so on.

Alcohol

During treatment Termikonom alcohol is strictly prohibited.

Reviews Termikone

In general, reviews of tablets Termikon related to the treatment of complicated fungal infections   feet or skin multi-colored lichen . Indeed, this form of drug therapy is indicated when external funds have not brought the desired effect.

Also, there are reviews of spray Termikon in which the patient is told about its use during treatment candidiasis . From this report it becomes clear that a timely initiated therapy with the strict observance of rules of personal hygiene, use of additional resources allows you to quickly resolve this violation.

In addition, as shown by reviews of ointment Termikon, this tool is actively used in the treatment of various fungal infections . It was found that at the initial stage ointment Termikon exhibits the highest activity.

As is known, fungal infections   They are among the most common. Many people may not realize immediately that patients with mycosis. Moreover, even after the occurrence of unpleasant symptoms, some patients are not in a hurry to the doctor, trying to restore the health of self-treatment. Since taking the drug, and some even do not know exactly from what ointment, and how it differs from its analogues. In order not to harm the health of a similar activity can be used only on prescription.

Price Termikona where to buy

Price Termikon tablets with an active substance content of 250 mg are in the range 412-910 rubles, depending on the number of tablets in the pack.

Price Termikon spray for external application of 1% is 240-320 rubles.

Price Termikon ointment for external application of 1% may be 155-250 rubles.

Ukraine Termikon cream can be purchased for 134-140 UAH., Spray - 210-250 UAH., And tablets - in the range of 330-350 USD.

Get the best price and buy