Cavinton

Description overdue on 16.10.2011

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The main active substance - vinpocetine . It refers to a group tserebrovazodilatiruyuschih funds . PM improves cerebral metabolism . cerebral circulation Rheological properties of blood. Cavinton has cerebroprotective action significantly reduces the severity of the damaging effect amino acids It inhibits the activity of transmembrane calcium, sodium channel receptors AMPA . NMDA . The drug has a potentiating effect on neuroprotection adenosine . Vinpocetine increases the absorption, improves the absorption, metabolism of oxygen and glucose by the brain. The drug is able to move the glucose metabolism in a more favorable direction aerobic energy. It stimulates cerebral metabolism Serotonin   and noradrenaline , Having antioxidant . stimulatory   impact on the noradrenergic system.

Cavinton selectively improves cerebral blood circulation: increases cerebral fraction of cardiac output, lowers the resistance of the blood vessels of the brain, without affecting the general circulation in the ( Heart Rate . minute volume . BP . PR ). The drug does not cause syndrome "steal". It improves blood circulation ischemic But viable regions of the brain, causing the phenomenon of "reverse steal." Increases resistance to brain cells hypoxia Improves microcirculation Reduces platelet aggregation opposed abnormally high viscosity of blood increases the deformability of erythrocytes, has a blocking effect on the uptake of adenosine erythrocytes .

Dosage Form:

The tablets in the blister pack. Solution for injection.

Indications:

Neuroscience : Transient ischemia , Vascular Dementia Progressing stroke . atherosclerosis   GM vessels, vertebrobasilar insufficiency, post-stroke, hypertensive, post-traumatic encephalopathy, and other types of cerebrovascular insufficiency. Neurological, psychiatric disorders in patients with cerebrovascular insufficiency ( aphasia , Memory impairment, apraxia, headaches, movement disorders).

Ophthalmology : Vascular eye disease (vasospasm retina and choroid, atherosclerosis, degenerative diseases, secondary glaucoma , Thrombosis, embolism ).

Otorhinolaryngology : Hearing impairment age, toxic and vascular genesis, kohleovestibulyarny neuritis, Meniere's disease, vertigo, tinnitus, vasovegetative symptoms in menopause.

Contraindications:

Severe forms of arrhythmia, severe coronary artery disease, lactation, pregnancy (due to lack of safety data).

Side effect:

Cardiovascular system : Strengthening of existing arrhythmias can tachycardia, drop in blood pressure. Gastrointestinal tract : Dyspepsia, dry mouth, heartburn . Central nervous system Weakness, insomnia, dizziness, headache. Allergies.

Mode of application:

The course of treatment an average of 3 months (permissible from 1 to 8). Cavinton take before meals, three times a day for 1 m. For the abolition of the drug dose should be reduced gradually over a period of 3 days. The solution Cavinton introducing drip / in a dose of 20 mg per 1000 ml saline. solution.

Special instructions:

Cavinton has no nephrotoxicity and hepatotoxic effects. Patients with lactose intolerance should be considered that 1 tablet contains 83 mg of lactose. Patients with diabetes   when parenterally administered drug requires monitoring of blood glucose (solution contains sorbitol At / in the introduction increases the risk of arrhythmia, ventricular fibrillation). When cerebral hemorrhagic stroke drug can be administered parenterally only after decrease in acute phenomena (after 5-7 days.). The drug is not recommended for appointment in pediatrics.

Drug Interactions:

Use of the drug in the background Cavinton Heparin   It increases the risk of developing a variety of hemorrhagic complications. LAN solution for injection is not compatible with Heparin .