Dekaris

Description overdue on 14.03.2012

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Anthelminthics . Active Ingredient - levamisole . It is based on membrane depolarization of muscle tissue parasites fumaratreduktazy oppression, blocking of succinate dehydrogenase, that as a result leads to an imbalance of the flow of bioenergetic processes in the body helminth. Dekaris activates T lymphocytes, enhances antibody production in response to various antigens, activity increases monocytes It enhances T cell response, stimulates lymphocyte proliferation It activates neutrophils, macrophages (increasing their ability to phagocytosis, adhesion, chemotaxis). The drug has Dekaris immunomodulatory effects . Dekaris is available in tablet form.

Indications:

Dekaris prescribed for toxoplasmosis , Enterobioze, trihotsefaleze , Trihostrongileze, strongyloidiasis, hookworm , Ascariasis, necatoriasis.

Contraindications:

Dekaris not indicated during pregnancy, intolerance of levamisole, medication   agranulocytosis In pediatric patients until the age of 14. In acute leukemia, inhibition of bone marrow hematopoiesis, renal disease and liver used with caution.

Side effect:

The digestive tract:   level increase alkaline phosphatase , Diarrhea, dyspepsia, vomiting, nausea, pancreatitis It is rarely recorded ulceration of the mucous wall of the oral cavity. Nervous system : paresthesia , Headaches, olfactory hallucinations . generalized seizures , Speech disorders, entsefalopodobny syndrome   (a process called demielinizirovaniya nerve fibers), lethargy, peripheral polyneuropathy Rarely recorded ataxia, confusion, dream abnormality, tremor of limbs, fatigue. Dekaris cause vasculitis , Iridocyclitis, myasthenia, periorbital edema, lymphadenopathy , Taste perversion, uterine bleeding.

Mode of application:

Dekaris tablets taken with food. Helminthiasis:   bedtime once taking 150mg of levamisole, the dose for children is calculated according to the scheme 2, 5 mg per 1 kg of body weight. Toxoplasmosis:   Three days taking 150 mg. If necessary, repeat 2-3 times a week with a break.

Special instructions:

Anthelmintic therapy requires leukocyte level control before applying medicament examined peripheral blood. Previously Dekaris used as an immunomodulator in the pathology of the immune system, autoimmune diseases .

Drug Interactions:

Dekaris incompatible with ethanol (high risk for disulfiramopodobnyh reactions ), Lipophilic compounds prepraty that cause leukopenia. Levamisole is able to enhance the activity anticoagulants , Phenytoin. Gematoksichnost drug significantly increased, while the body is myelotoxic drugs .