Description overdue on 10/12/2014
- Latin name: Lordestin
- ATC code: R06AX27
- Active substance: Desloratadine (Desloratadine)
- Manufacturer: Gedeon Richter-RUS (Russia)
- Composition
- Product form
- Pharmacological action
- Pharmacodynamics and pharmacokinetics
- Indications
- Contraindications
- Side effects
- Lordestin - application instructions (method and dosage)
- Overdose
- Cautions
- Cooperation
- Terms of sale
- Storage conditions
- Shelf life
- Analogs
- With alcohol
- Reviews
- Price, where to buy
Composition
The drug contains the active ingredient: desloratadine hemisulfate.
Excipients: MCC, calcium hydrogenphosphate dihydrate, pregelatinized starch, colloidal silicon dioxide and magnesium stearate.
The composition of the shell membrane consists of: Opadry AMB yellow 80W22099 or partially hydrolyzed polyvinyl alcohol, talc, titanium dioxide, lecithin, aluminum lake that is based on quinoline yellow dye and the dye indigo carmine, gum iron oxide yellow and xanthan.
Product form
Available Lordestin in the form of tablets, coated foil wrapper 5 mg, placed in blisters of 10 pieces. The pack includes 1 or 3 blisters.
Pharmacological action
Lordestin has antiallergic action.
Pharmacodynamics and pharmacokinetics
The active component of the drug prevents the development and greatly facilitates the manifestation of allergic reactions. To desloratadine characteristically antiallergic, antipruritic and protivoekssudativnoe action. In addition, it decreases capillary permeability, which prevents the development of tissue edema. The drug does not have the bright sedative effect, so its use in therapeutic doses has no special influence on the speed of psychomotor reactions.
Inside the body desloratadine fully absorbed from the gastrointestinal tract. The concentration of active substance in the blood is determined by half an hour. The maximum concentration of desloratadine in the composition of the plasma levels achieved after 30 minutes. When this component is proportional to the dosage bioavailability.
Desloratadine and 3-gidroksidezloratodin at 83-89% bound to plasma proteins. Simultaneous food intake or fruit juice has no effect on the bioavailability or distribution desloratadine . It does not set the penetration of the component through the BBB. The metabolism of a substance in the liver. Excretion occurs mainly as the glucuronide compound and a small part in unchanged form by means of the kidneys and intestines.
Indications
Lordestin The drug is indicated for:
- seasonal allergic rhinitis In order to relieve symptoms - sneezing, rhinorrhea, itching, nasal congestion, itchy eyes, watery eyes, redness of the eyes, itching of the mouth, cough;
- chronic idiopathic hives - Rash and itching.
Contraindications
Do not take this medicine if:
- hypersensitivity to its components;
- lactation, pregnancy;
- children's age less than 12 years.
Compliance must be caution in severe renal disease.
Side effects
Admission Lordestina can cause side effects such as fatigue, dry mouth and headache.
It is also possible to develop: dizziness, tachycardia, palpitations, abdominal pain, dyspepsia, hyperbilirubinemia , Increasing the activity of hepatic enzymes, hepatitis allergic reactions and so on.
Lordestin - application instructions (method and dosage)
Lordestin tablets intended for oral administration as a whole. As recommended instructions for use Lordestina, it should carry out every day at the same time, regardless of the use of food, with some liquid.
For adults and adolescents from 12 years - the average daily dose is 5 mg or 1 tablet.
If patients suffer from chronic renal failure and liver failure, then the correction of dosing regimen. In such cases, the starting dose of 5 mg a day appointed by regularly observing the patient's condition.
Overdose
The main symptom of overdose is drowsiness .
In such cases, appoint a gastric lavage, reception Activated Carbon , Symptomatic therapy. It is known that the drug can not be output by hemodialysis.
Cautions
It was found that taking this drug does not affect the ability to drive vehicles and other mechanisms. But since patients are often concerned about the drowsiness , You should be careful, especially if side effects manifest in the activities of the central nervous system.
Cooperation
Simultaneous reception and Lordestina ketoconazole . erythromycin, azithromycin, fluoxetine . cimetidine and other drugs causes particular changes of the active substance in blood plasma.
Terms of sale
The drug is available without a prescription.
Storage conditions
Tablets should be stored in a dark place, safely protected from children, at temperatures up to 25 C.
Shelf life
4 years.
Analogs Lordestina
Dramina
Lomilan
Fenkarol
Kestin
Loratek
Aerius
Feksadin
Claritin
Telfast
Loratadine
Diazolin
The main counterparts are presented Lordestina drugs: Aerius, Fenistil, desloratadine, Tavegil, Canon, desloratadine hemisulfate, loratadine, Ezlor, Nalorius and others.
Lordestin or Aerius - which is better?
One of the main counterparts is Lordestina Aerius . As the clinical practice, these allergy medications prescribed for seasonal relapses. Therefore, many patients worried about the question of which of these drugs is better?
However, according to experts, both drugs have virtually the same effect. Before you choose a medication, you should consult with your doctor. Understand whether helping each patient to a particular drug can be used only during treatment. Also, people suffering allergic reactions must adhere to the rules and other diet and lifestyle in order not to provoke the development of reactions.
Alcohol
During treatment Lordestinom it is not recommended to drink alcohol Even though he has no inhibitory effect on psychomotor functions. However, we should not exclude the gain of allergic symptoms and the development of side effects.
Reviews Lordestine
Online reviews of Lordestine abound. At the same time the opinion of patients on this drug has developed extremely diverse.
Especially well this tool helps to eliminate the symptoms of allergies such as allergic rhinitis. Also, there are reports that these pills can be assigned during a severe swelling of the nasal mucosa with colds.
This drug is actively used allergies suffering from this disease for several years and in mild cases of the disease. Many have noted the development of rapid and consistent effect.
However, not all users were satisfied with the action Lordestina. They claim that the drug does not bring them even the slightest relief. Moreover, in the course of treatment, patients reported the development of strong headaches .
As is known, allergic reactions characterized by an individual for. For this reason, for the treatment of this disease there is no standard therapeutic doses. Usually during the selection of competent treatment patients have to try a few antihistamines . Only after this, it becomes clear whether drug restore health or cause unwanted effects. Of course, all this must be carried out under the supervision of a competent doctor.
Price Lordestina where to buy
Price Lordestina pharmacies in the Russian regions is virtually identical. However, this drug can be purchased at any pharmacy. Price 10 tablets Lordestina ranges 220-330 rubles.
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