Description overdue on 04/10/2014
- Latin name: Cytoflavin
- ATC code: N07XX
- Active substance: Succinic acid, nicotinamide, Riboxinum, Riboflavin
- Manufacturer: NTFF Polysan Ltd., Russia
- Composition
- Product form
- Pharmacological action
- Pharmacodynamics and pharmacokinetics
- Indications Cytoflavin
- Contraindications
- Side effects
- Instructions for use Cytoflavin (method and dosage)
- Overdose
- Cooperation
- Terms of sale
- Storage conditions
- Shelf life
- Analogs
- During pregnancy (and lactation)
- Reviews
- Price, where to buy
Composition
One ml of the drug contained 0, 1 succinic acid 0 01 nicotinamide 0 02 Riboxin 0 002 riboflavin + Adjuvants ( sodium hydroxide Injectable meglumine ).
One tablet: 0, 3 succinic acid 0 riboksina 05, 0, 025 nicotinamide, 0, 005 + riboflavin adjuvants ( povidone, calcium stearate, propylene glycol, dye ).
Product form
- The drug in ampoules, injection. Transparent yellow liquid.
- In tablets, the convex shape of the coated red (orange or yellow inside) contour packing 10 pieces in boxes of 5 and 10 packs.
Pharmacological action
INN medications: Inosine + nicotinamide + Riboflavin + Succinic Acid (Inosine + Nicotinamide + Riboflavin + Succinic acid). Drugs affecting central nervous system Affecting metabolism .
Pharmacodynamics and pharmacokinetics
The action of the drug due to the sum of the components included in its composition:
Succinic acid - Important participant Krebs cycle . Transformed into fumaric acid which in turn becomes an active participant in the cycle TCA . Because of succinic acid occurs ATP synthesis and flow processes glycolysis . By the end of the loop releases carbon dioxide and H2O.
Inosine participates in establishing the key enzymes in the Krebs cycle nucleotides, such as FAD and ABOVE . Takes part in the synthesis of ATP.
Riboflavin - Vitamin B2 is also directly involved in the Krebs cycle.
Nicotinamide (Krebs cycle) is transformed into ABOVE and NADP Which, in turn, stimulate cellular respiration and ATP synthesis.
Indications Cytoflavin
From what Citoflavin pills?
- cerebrovascular accident (the state after stroke );
- indication to the use of drugs is the inability of a person for a long time in a state of mental and physical stress;
- at Cerebral ischemia in infants (and premature);
- prophylaxis after surgery, during which the use of artificial blood circulation;
- cerebral atherosclerosis .
Contraindications
The drug should not be taken to persons under 18 years of age, patients with kidney disease, when allergies the drug components. Tablets should not be taken in diseases of the stomach.
Side effects
It occurs infrequently. FEATURES: headache, tachycardia and arrhythmia , Change Blood Pressure and ECG . nausea and vomiting , Allergic reactions, urine may turn yellow, general weakness, poor thermoregulation .
Instructions for use Cytoflavin (method and dosage)
Instructions on Citoflavin tablets Usually administered 2 tablets 2 times a day, morning and evening, with an interval of 7 hours. The drug is taken half an hour before meals. Do not chew tablet. The course is 25 days, if necessary, it can be repeated after one month.
Medicine in ampoules : Assign an intravenous drip. Enter the drug via injections impossible. IV makes 100-200 ml of solution Glucose or NaCl. The daily dose for adults is 10 ml (up to 20 in serious condition), treatment depends on the disease, and can be up to 10 days.
For newborns optimum time of administration is considered to be from 2 to 12 hours. For drip preparation is diluted with glucose in a ratio of 1: 5 and 2 mL per kilogram of body weight throughout the day. The average course of treatment - 5 days.
Overdose
No cases of overdose were reported.
Cooperation
Applying medication with antibiotics and especially with streptomycin It reduces the efficiency of the latter.
Thyroid hormones enhance the effect of the drug, ethanol and antidepressants conversely lower.
Terms of sale
It requires a prescription.
Storage conditions
In a dark, cool, the children, the temperature regime - no higher than 25 degrees. If the bottom of the solution appeared sediment can not use the vial.
Shelf life
The medicine can be stored for 12 months.
Analogs Cytoflavin
Mexidol
Neurox
Glitsised
Glycine
Boluses Huato
At present, there are no medicines with the same set of operating components. There are similar products: antifront, armadin, boluses Huato, borizol, glycine, glitsised, glutamic acid, cortexin meksiprim, neurotrophin, nikomeks, rilutek and others. Price analogs differ depending on the manufacturer and the composition.
During pregnancy and lactation
The drug is not recommended for use. The drug can be administered at the doctor hypoxia the fetus of varying severity has good reviews during pregnancy.
Reviews cytoflavin
Well, there are practically no negative. Tablets are well tolerated, adverse reactions occur very rarely. Almost all people taking the medication prescribed by a doctor, there is a marked improvement in health.
Reception children reviews No clinical data are Cytoflavin for children. Despite the fact that the medication is not recommended, it is often prescribed for developmental delay and other abnormalities. Reviews often good, some people notice a positive change after the first course. The drug is well tolerated and is used in the treatment.
Price Citoflavin where to buy it?
The price of the tablet Cytoflavin in Ukraine on average 120 UAH for 50 pieces.
The price of a vial of 10 ml - 38 UAH 5 ml ampoules of about - 20 UAH.
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