Wednesday, August 23, 2017

Dibazol

Description overdue on 24.06.2012

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 Dibazol  Vasodilators . Active ingredient -   bendazol . The drug has a vasodilator, hypotensive, mild immunostimulatory effects , Has a stimulating effect on the operation of the spinal cord. Dibazol has antispasmodic effect   against smooth muscle tissue of internal organs, blood vessels. In the spinal cord facilitates bendazol synaptic transmission . Immunostimulatory effects are associated with the regulation of immune cells in a concentration ratio of cAMP and cGMP, which leads to proliferation sensitized mature B- and T-lymphocytes, activation of effector functions of cells of finite, cooperative reaction secretion factors mutual regulation. Dibazol has a moderate hypotensive, short exposures, is well tolerated. The drug is recommended for use when sclerosis of cerebral arteries , Chronic hypoxia, cerebral vascular disturbances in the brain, as It is a short extension of cerebral vessels. Dibazol available in tablet form, in the form of suppositories, solution.

Indications, contraindications:

Dibazol prescribed for hypertension, ulcerative lesions of the gastrointestinal tract, koronarospazm , Hypertensive crisis, renal colic, spasm of smooth muscle, hepatic colic , Polyneuritis, peripheral facial paralysis, when intestinal colic, residual effects of polio. Dibazol does not apply in case of intolerance bendazol. In the elderly causes a decrease in the IOC used with caution.


Side effect:

High doses bendazol cause headache, dizziness, increased perspiration , Hot flashes, nausea, allergic response.

Mode of application:

Dibazol for hypertensive crisis must be administered intravenously / intramuscularly in 3 ml of 1% solution / 6 ml 0, 5% solution. With a significant rise in blood pressure without symptoms during krizovoe bendazol administered 2-3 times a day, 4-8 ml of 0 5% solution or 2-4 ml of 1% solution. A tablet form of the drug take 3-4 weeks every day 2-3 times a day 20-40mg. In diseases of the nervous system of the adult prescribe 5-10 times a day, 5 mg, the drug can be taken in a day. After a month of therapy bendazol repeated. In the following courses are conducted at intervals of 2 months. Dibazol for children under one year is appointed in a dosage of 1 mg.

Special instructions:

Dibazol not intended for long-term therapy, particularly for the elderly. Dibazol children prescribe a course of strict compliance with the dosing regimen.

Drug Interactions:

Dibazol able to prevent the increase of peripheral vascular resistance, caused by taking non-selective group beta-blockers . Phentolamine increases the severity of the hypotensive effect of the drug. Bendazol enhances the hypotensive effect of diuretics, antihypertensive drugs.

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