Description overdue on 01/10/2014
- Latin name: Omez
- ATC code: A02BC01
- Active substance: Omeprazole (Omeprazole)
- Manufacturer: Dr. Reddy's Laboratories Ltd. (India)
- Composition
- Product form
- Pharmacological action
- Pharmacodynamics and pharmacokinetics
- Contraindications
- Side effects
- Instructions for use omez (method and dosage)
- Overdose
- Cooperation
- Terms of sale
- Storage conditions
- Shelf life
- Cautions
- Analogs
- Babies
- With alcohol
- During pregnancy (and lactation)
- Reviews
- Price, where to buy
Composition
The composition of capsules include the active ingredient omeprazole As well as additional ingredients: dibasic sodium phosphate, sucrose, sodium laurylsulfate, purified water. The drug is also produced in the form of lyophilized powder, which is used to prepare a solution. It also includes the active ingredient omeprazole And excipient anhydrous sodium carbonate.
Product form
Release form of the drug - capsules and powder.
Hard gelatin capsules, the capsule body - transparent cover has a pink color. The inscription «OMEZ» is on both sides of the capsule. The capsule is filled with white granules. The package holds 10 or 30 capsules.
Also available as a lyophilized powder, used to prepare the solution for induzy (Omez w / w). The bottle holds 40 mg of the drug.
Pharmacological action
As the abstract, this medicine is the anti-ulcer drug which belongs to the group of proton pump inhibitors. The active substance is omeprazole, which accommodates a capsule inhibits acid secretion, exerting a specific effect on the enzyme H + -K + -ATPase stomach cells. As a result, under the influence of its locked last step of the synthesis of hydrochloric acid.
Pharmacodynamics and pharmacokinetics
Applying medication internally leads to rapid development of the effect: it is evident within 1 hour. Next tablet Omez operate 24 hours.
Once the medication is stopped, the secretory activity of the exocrine glands of the stomach is reduced in about 3-5 days. For omeprazole characterized by a rapid absorption from the intestine. Since the active substance in the drug contained in the granules are resistant to acid, they dissolve only in the intestine. In plasma, the highest concentration observed after 30-60 minutes. The level of bioavailability of omeprazole - 40%. Communication drug with plasma proteins - 90%.
Excreted through the kidneys.
When administered intravenously marked dose-dependent inhibition of gastric secretion. Half-life of omeprazole after intravenous administration is approximately 40 minutes.
Indications omez
Indications omez following:
- peptic ulcer, duodenal ulcer, stomach;
- erosive and ulcerative esophagitis;
- ulcerative processes that are associated with non-steroidal anti-inflammatory drugs;
- ulcers associated with stress;
- recurrent peptic ulcers, gastric or duodenal localization;
- Zollinger-Ellison syndrome;
- pancreatitis ;
- systemic mastocytosis.
If you can not receive the drug inside, but there are indications for use, the tool can be administered intravenously.
When Omez drink tablets, from which they still apply, inform the attending physician.
Contraindications to Omez
The following contraindications:
- Hypersensitivity;
- pregnancy and breast;
- children's age.
Beware of the capsule should be taken to people with kidney and liver failure. Method of use and dosage of the drug in this case must determine only an expert.
Possible side effects:
- Digestive system : Abdominal pain, nausea, flatulence , Taste disturbances, increased activity of liver enzymes.
- Bodies of blood: thrombocytopenia, leukopenia, agranulocytosis.
- Nervous system: headache, dizziness, depression.
- Locomotor apparatus : Myasthenia, arthralgia, myalgia.
- Skin : Rash, itching, photosensitivity.
- Allergic symptoms : hives , Fever, bronchospasm.
- In addition, in rare cases, there may be blurred vision, malaise, profuse sweating.
Instructions for use omez (method and dosage)
Instructions for use inside omez provides that the patient swallows the capsule without opening and without chewing.
If a peptic ulcer, reflux esophagitis appointed Omez tablets, instructions for use provided that the drug is used at a dose of 20 mg per day, in the morning, on an empty stomach. The drug should be taken 14 days. If peptic ulcers during the treatment period and not healed, the treatment may continue for another two weeks. Typically, when receiving means scarring peptic duodenal ulcer occurs after 4 weeks.
Treatment of Zollinger-Ellison syndrome involves daily administration of 60 mg drug. To learn how to drink - before or after meals, instruction and is an indication: the drug is taken before a meal. Supporting further dose prescribed by the physician.
With gastritis Treatment lasts from 1 to 2 weeks. Treatment of gastritis aimed at addressing the symptoms of stomach irritation. In this case, 1 capsule a day. For more information on how to take Omez gastritis, tell doctor after diagnosis.
If pancreatitis is appointed as a part of complex treatment. It is assumed that this treatment helps relieve the patient of heartburn, pain and reduce the burden on the pancreas. The duration of treatment depends on the severity of symptoms. Initially a day two capsules assigned further practiced maintenance therapy - 1 capsule per day. When heartburn should not be used without prior approval of such treatment a doctor.
Intravenously, depending on the disease, is carried out in a dose of from 40 mg to 80 mg per day. If the dose is 60 mg, it can be split into two administration. After removal of the acute symptoms practiced switching to oral agents. Cooked solution fit for the day.
Overdose
Wikipedia shows that an overdose of the drug does not cause life-threatening symptoms. In such a case, it may appear blurred vision, dry mouth, drowsiness, headache, tachycardia . Apply symptomatic therapy. Hemodialysis
Cooperation
At simultaneous reception may decrease the absorption of ampicillin esters, iron salts, ketoconazole, itraconazole.
Omeprazole increases concentration and reduces the activity of elimination of diazepam, indirect anticoagulants, phenytoin.
When combined oral omeprazole and clarithromycin increases the concentration of these substances in the blood plasma.
Terms of sale
The pharmacy Omez can be purchased by prescription.
Storage conditions
Store means you need a dry and dark place, at an air temperature not exceeding 25 ° C.
Shelf life
Shelf life of capsules - 3 years.
Cautions
You can receive capsules with food at the same time, from which the drug loses its effectiveness.
Before you start taking the capsules or drive Omez intravenously, should be excluded malignant processes, as treatment may mask the symptoms, thereby otstrachivaya diagnosis.
Sometimes, there are circumstances when it is necessary to avoid swallowing whole capsules, for which drug is used in the following way: the capsule is opened and the contents mixed with soft puree of apples (1 tablespoon).
It is unlikely the effect of the drug on the ability to drive vehicles and operate with precision equipment.
Analogs omez
Losek MAPS
Losek
Sanpraz
Emanera
Insta omez
Rabeprazole
Kontrolok
Ortanol
Nexium
Nolpaza
Geerdin
Omeprazole
Lansoprazole
There are imported and Russian counterparts omez, but to pick their own replacement is not recommended. Omeprazole . Demeprazol . Krismel . Zerotsid . Omekaps . . Gastrozol . Ultop et al. Price analogues depends on the manufacturer, and other factors.
Nolpaza or Omez - which is better?
Means Nolpaza It has similar effects by reducing the level of hydrochloric acid and eliminating the symptoms of diseases of the gastrointestinal tract. The structure includes Nolpaza active ingredient Pantoprazole.
Omez or Ranitidine - which is better?
Ranitidine contains the active ingredient ranitidine hydrochloride and applied under the same conditions and diseases as Omez. What preparation prefer depends on the doctor's prescription.
What is better - or Omez Ultop?
The structure of funds Ultop also includes the active ingredient is omeprazole. Its action is based on inhibition of the activity of gastric juice. Which drugs should be chosen, it is necessary to ask a specialist and at the same time take into account the diagnosis.
Ortanol or Omez - which is better?
Ortanol - Another drug active substance is omeprazole. As Omez, this drug is prescribed for peptic ulcer, and other hypersecretory states.
What is better - or Omez Pariet?
Pariet However, the indications for use of this remedy are the same as in capsules Omez.
What is better - or Omez De Nol?
- Antiulcer agent which contains bismuth subcitrate. How to take Omez and De Nol, it depends on the severity and characteristics of the disease. But this should be done under the scheme prescribed by the doctor.
What is better - or Omez Omez D?
Many patients are interested in the difference Omez Omez and D. The difference between these drugs is that Omez D It comprises as active ingredient not only omeprazole but also domperidone.
Babies
The medicine is not administered to children under 12 years of age, as sufficient information on its effects on the body of young patients there.
With alcohol
Compatible with alcohol: despite the fact that there is no information in the instructions that omeprazole in the treatment of alcohol is forbidden, according to the doctors, the treatment of the drug can not drink alcohol.
Omez during pregnancy and lactation
During pregnancy and breast-feeding the baby milk treatment with this drug is not practiced.
Reviews omez
There are numerous positive reviews omez. Guest host this facility indicate that it effectively treats peptic ulcer, it helps to overcome attacks Heartburn It eliminates the symptoms of acute gastritis. Reviews omez forms on the positive, people say that it can be taken at any time, and it works equally effectively. In addition, the drug improves the condition of the gastrointestinal tract in the treatment of other drugs that affect the stomach and intestines annoyingly. As drawbacks often mentioned that the means is quite expensive.
Price omez where to buy
Price Omez 20 mg - from 170 rubles per pack of 30 capsules. Price omez in Moscow and other Russian cities is similar. Buy Omez 20 mg in Ukraine (Kiev, Kharkov, and other cities) can be an average of 60 UAH. (package of 30 pcs.) Price Omez 10 mg - an average of 25 UAH. How much is the drug more accurately to find out directly at the point of sale.
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