Description overdue on 10/13/2014
- Latin name: Mycospor
- ATC code: D01AC10
- Active substance: Bifonazole (Bifonazole)
- Manufacturer: BAYER PHARMA (Germany)
- Composition
- Product form
- Pharmacological action
- Pharmacodynamics and pharmacokinetics
- Indications
- Contraindications
- Side effects
- Instructions on mikospor (method and dosage)
- Overdose
- Cooperation
- Terms of sale
- Storage conditions
- Shelf life
- Cautions
- Analogs
- Babies
- During pregnancy (and lactation)
- Reviews
- Price, where to buy
Composition
100 ml of a solution containing 1 g bifonazole . Additional components: isopropyl myristate and 96% ethanol.
100 g of cream contain 1 g of bifonazole. Additional components: stearyl alcohol, sorbitan stearate, benzyl alcohol, purified water, cetyl palmitate, cetyl alcohol, polysorbate, octyldodecanol.
Product form
Antifungal available as solution and in bottles cream in the box. Vials of 15 ml equipped with a special dropper and packed in cardboard boxes. Aluminium tubes are equipped with a screw cap and packed in bundles of cardboard.
Pharmacological action
Bifonazole is a major component, and belongs to the imidazole series . The active substance has antifungal activity . Fungistatic effect was observed when exposed to athlete , Trichophyton and Microsporum; fungistatic activity is observed upon contact with moldy and yeasts. Cream mikospor able detrimental impact on some gram-positive Corynebacterium and cocci. The peculiarity of the active ingredient is that it has not formed a secondary resistance.
The mechanism of anti-mycotic effects based on the suppression of the biological synthesis of the enzyme ergosterol under two possible paths, allowing destroy the fungal cell at the structural and functional levels.
Pharmacodynamics and pharmacokinetics
Active substance easily penetrates into the fungal infection layers epidermis . In the stratum corneum concentration bifonazole 6 hours index reaches 1000 g / cm3, for the destructive mildew.
The drug is absorbed only slightly when applied to healthy parts, it does not cause systemic responses. Absorption enhanced by applying the solution to the inflamed tissue. The active substance can penetrate through placenta That is confirmed in experiments on rats.
Indications
Mikospor ointment and solution are prescribed for diseases of the skin caused by by mold by fungi , Dermatophytes, Corynebacterium, the yeast:
- candidiasis of the skin (superficial forms);
- tinea groin area;
- mycosis of hands;
- chromophytosis;
- interdigital tinea;
- mycotic lesions feet;
- erythrasma;
- tinea smooth skin.
Contraindications
During the period of gestation pregnancy the drug is not prescribed. The drug is contraindicated in individual hypersensitivity to bifonazole. In pediatric medication is not applicable.
Side effects
May appear peripheral edema, pain, allergic responses , Burning, eczematous changes, blisters, itch . dermatitis , Maceration in applying the cream and solution. After completing antifungal therapy side effects disappear.
Instructions on mikospor (method and dosage)
Scheme and duration of antifungal therapy determined by the attending doctor. The cream is applied on the affected the field 1 time per day, vtiraya in neat, light movements. The procedure is best carried out before bedtime. Continuous treatment can achieve better results.
When the superficial candidiasis instruction in the form of an ointment recommends treatment for 2-4 weeks. When pityriasis versicolor and erythrasma - 2 weeks; when of mycotic the defeat of - 2-3 weeks.
Three drops of the solution (or lotions column 1 cm) is sufficient to handle the 1% of body area (corresponding to the size of the palm).
Overdose
Reliable information not.
Cooperation
Active component practically not absorbed and not shall enter into contact with other medicinal means.
Terms of sale
OTC medicines.
Storage conditions
The cream and the solution is recommended to hide from children. Storage temperature does not affect the quality of the product, up to 25 degrees.
Shelf life
Tubes and bottles can be stored 5 years.
Cautions
With of drug allergy other medicines protivomikoticheskie history ( Miconazole . Econazole and Clotrimazole ) Treatment should start with small doses, estimating the overall response. Protect your eyes.
When intolerance cetostearyl alcohol instead of ointment recommended solution.
Analogs
Travokort
Mikospor Set
Dermazol
Zalain
Bifosin
Amiklon
Nizoral
Miconazole
Clotrimazole
- Bifosin;
- Bifaces;
- Fukortsin.
Babies
Data on the clinical studies conducted there. In practice, the adverse reactions in children were not recorded. For Kids up to 1 year appoint at possibilities regular inspection of the child's doctor.
During pregnancy (and lactation)
Topical administration does not lead to absorption of the active component. Studies confirm that bifonazole no effect on fetal development and the health of women during pregnancy . However, treatment is recommended when evaluating the benefit of mother and risks to the unborn child.
Whether the active substance penetrates into breast milk is not currently known. It is also recommended to evaluate the risks and potential benefits. Cream on the thoracic region of the mammary glands is unacceptable when applied lactation.
Components mikospor not affect the fertility men and women.
Reviews mikospor (opinion of doctors and patients)
The treating doctor prescribed medication in the active treatment of mycotic lesions of the skin. Reviews mikospor at nail fungus only positive, preferable to use Mikospor Set Which further comprises a patch and a scraper.
Price mikospor where to buy
The cost of anti-fungal medication depending on sales region. In some cases, easier, and cheaper to order medication online pharmacies. Thus, the cream delivery will cost 380 rubles, while the price in the ointment mikospor pharmacy is 440 rubles. Price mikospor in Ukraine - 105 UAH for cream and 280 USD for a solution.
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