Diklovit

Description overdue on 07/12/2014

• Latin name: Diclovitum
• ATC code: M02AA15
• Active substance: Diclofenac sodium (Diclofenac sodium), Thiamine Hydrochloride (Thiamin hydrochloride), Pyridoxine hydrochloride (Pyridoxini hydrochloridum), cyanocobalamin (Cyanocobalamin)
• Manufacturer: Valium (Russia)

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• Composition
• Product form
• Pharmacological action
• Pharmacodynamics and pharmacokinetics
• Indications
• Contraindications
• Side effects
• Instructions for use Diklovita (method and dosage)
• Overdose
• Cooperation
• Terms of sale
• Storage conditions
• Shelf life
• Reviews
• Price, where to buy

Composition

The active ingredient of the drug in the form of Candles   and gel - diclofenac sodium .

Candles Diklovit have the following additional components: witepsol, suppozir.

Additional components of the gel: rectified ethyl alcohol, 40% lactic acid, carbopol, purified water, isopropanol, sodium bisulfite, trolamine.

Capsules It contains active ingredients such as diclofenac sodium, pyridoxine hydrochloride, thiamine hydrochloride, cyanocobalamin. Auxiliary elements - povidone, triethyl citrate, iron oxide red, titanium dioxide, methacrylic acid, talc, iron oxide yellow, gelatin.

Product form

In pharmacies sold Gel Diklovit , and capsules and Candles .

Pharmacological action

The drug belongs to NSAIDs.

Pharmacodynamics and pharmacokinetics

This drug has anti-inflammatory . antipyretic . anesthetics   and antiagregatsionnogo   properties. At the heart of its action is inhibition of the activity I cyclooxygenase   and II . This causes a disturbance metabolism   arachidonic acid. In turn the synthesis prostaglandins   reduced inflammation at the site. Joint pain is reduced at rest and in motion. Fade or dull morning stiffness, joint swelling. The drug also helps to increase the range of motion in the joints.

The drug reduces the pain syndrome   in traumatic and postoperative pain, as well as the severity of inflammatory reactions. Decreases bleeding   and pain in primary algodismenoree .

When using spark maximum concentration visible in half an hour.

Indications

The drug is used for:

• lumbodynia ;
• inflammatory and degenerative diseases of the locomotor system;
• frozen shoulder ;
• lumbago ;
• bursitis ;
• neuralgia ;
• inflammation, lockjaw , Pain, edema   because dental, gynecological, orthopedic and other interventions;
• myalgia ;
• synovitis ;
• tenosynovitis ;
• posttraumatic pain syndromes ;
• attacks migraine ;
• postoperative pain;
• colic .

The use of candles in gynecology Diklovit shown at primary dysmenorrhea . perimeter . adnexitis . In addition, it may be an additional means as belonging to the combined treatment of infectious and inflammatory diseases of upper respiratory tract that are accompanied by a pronounced sense of pain.

Contraindications

Do not use the tool in case of hypersensitivity to its components and other NSAIDs . violations of hematopoiesis   unknown origin "Aspirin" asthma . pregnancy , Exacerbation ulcers of the stomach and duodenum , Exacerbation erosive and ulcerative lesions   Gastrointestinal tract, "Aspirin" triad , Children younger than 6 years. With care, he was appointed to the case, induced acute hepatic porphyria As well as problems with the liver and kidneys.

Side effects

The drug can cause the following side effects:

• digestive system - ulcerative colitis   in the acute stage, gastralgii , Vomiting, pain in the stomach, constipation . anorexia , Bleeding in the gastrointestinal tract, fulminant hepatitis . if nonspecific t   bleeding, Crohn's disease   being increased, nausea, diarrhea . dyspepsia . flatulence Increase in activity hepatic transaminases . pancreatitis . hepatitis ;
• urinary system - hematuria , Acute renal failure . nephrotic syndrome . proteinuria . papillary necrosis . interstitial nephritis ;
• skin - skin rash, eczema . exfoliative dermatitis , Photosensitivity, bullous   rashes, erythema multiforme . alopecia . purpura ;
• nervous system - headache , Severe fatigue, paresthesia , Disorientation, diplopia , Tinnitus, irritability, depression , Nightmares, psychotic reactions . dizziness . confusion , Memory loss, blurred vision and hearing, insomnia , Seizures, anxiety . tremor , Taste disturbance;
• hematopoietic system - thrombocytopenia . agranulocytosis . aplastic   and hemolytic anemia . leukopenia ;
• allergy   - allergic purpura . bronchospasm . hives . Stevens-Johnson syndrome . Lyell's syndrome . anaphylactic state ;
• Other - swelling , Breast tenderness, increased arterial pressure . impotence , Palpitations;
• Local reactions - mucus mixed with blood, irritation of the colon, pain in the defecation .

Side effects depend on the individual characteristics of the course and duration of dosing.

Instructions for use Diklovita (method and dosage)

The medicine can be used in adults and children from 15 years. Candles introduced rectally rectum after enema or bowel. If their use is necessary to lie down for 20-30 minutes. If you use candles Diklovit, instruction on the application reports that the need to put them twice a day. Maximum per day can be used 3 suppository .

Application Instruction Diklovita indicates that the duration of treatment is determined individually depending on the nature of the disease and individual tolerability.

The ointment is intended for external use. The strip of 1-2 cm with a thin layer is applied over the site of inflammation 2-3 times a day. It is necessary to rub not strong movements until complete absorption. The therapy lasts longer than 2 weeks. Extend a course is possible only after consultation with a specialist. After using the gel to wash your hands.

The capsules should be taken with meals, thus necessarily drinking plenty of fluids and not liquid. As a rule, the dosage of 1 capsule of 1 to 3 times daily. Adult daily administered 3 doses at the beginning of the course. The maintenance dose - 1 capsule 1-2 times / day.

Children from 6 years, give a maximum of 2-3 mg of the agent per 1 kg of body weight.

How many pills are taken, it depends on a doctor's prescription.

Overdose

Overdose suppository   unlikely. In applying the drug in high doses may headache . dizziness . hyperventilation Side effects from the stomach, dizziness. Children may appear pain in the abdomen, myoclonic seizures , Nausea, vomiting, problems with the liver and kidneys. In case of accidental use of funds orally   It recommended to wash out the stomach and take Activated carbon . Next symptomatic therapy.

Cooperation

Diklovit increases the plasma Digoxin , Drugs lithium and Phenytoin . It also inhibits the action of diuretics   and antihypertensive   drugs. When combined with potassium-sparing diuretics   It may even develop hyperkalemia .

Interaction with other NSAIDs   or glucocorticoids   It increases the likelihood of adverse reactions from the gastrointestinal tract. Combination with acetylsalicylic acid   It reduces the content of active substance Diklovita serum.

Together with the admission Cyclosporine   increases its toxic effects on the kidneys. A antidiabetic in combination with drugs can cause Diklovitom hypo-   or hyperglycemia . Therefore it is necessary to constantly monitor blood sugar.

The combination Methotrexate   with Diklovitom (during the day before or after ingestion) may cause an increased level of Methotrexate   and increased its toxic effects. When used anticoagulants   it is necessary to control blood clotting.

Terms of sale

Sold by prescription specialist.

Storage conditions

Keep the drug should be at a temperature of 25 ° C.

Shelf life

Shelf life of candles - 2 years, and the gel capsules - 3 years.

Reviews

As a rule, Diklovit received positive feedback. Those who use this tool in a variety of forms, mark its quick effect. Patients are satisfied that the drug has multiple actions: reduces swelling, removes inflammation, dulling the pain and so forth. However, reviews of candlelight Diklovit in gynecology sometimes report the personal medication intolerance, but symptoms of adverse reactions are rapidly with decreasing dosage. Among the disadvantages of gel note only that it has to be for a long time to rub that means completely absorbed.

Price Diklovita where to buy

Price Diklovita depends on the form of release. In general, it is considered very affordable among peers. Price gel about 80 rubles. Suppositories at most pharmacies are a little more expensive. The price of candles Diklovit about 90 rubles.

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