Description overdue on 10/13/2014
- Latin name: Mycospor Onychoset
- ATC code: D01AC60
- Active substance: Bifonazole + Urea (Bifonazole + Urea)
- Manufacturer: Bayer Pharma AG (Germany)
- Composition
- Product form
- Pharmacological action
- Pharmacodynamics and pharmacokinetics
- Indications
- Contraindications
- Side effects
- Instructions for use (method and dosage)
- Overdose
- Cooperation
- Terms of sale
- Storage conditions
- Shelf life
- Cautions
- Babies
- Reviews
- Price, where to buy
Composition
100 g of ointment contains 1 g bifonazole (micronized form) and 40 g urea . Additional Components: white beeswax, lanolin and white petrolatum.
Product form
Mikospor kit available as ointment, packaged in aluminum tubes of 10 g Each tube has a special screw cap of plastic. In addition to a cardboard bundle tubes are located scraper feeder and water resistant plaster.
Pharmacological action
The main component being bifonazole imidazole, has pronounced protivomikoticheskoy activity . Fungicidal (destructive) effect is in relation to dermatophytes . With long-term exposure (more than 6 hours) high concentrations (5 mg / ml), there is complete fungicidal effect .
Regarding fungi (mold, yeast) registered fungistatic activity. It is extremely rare resistant strains. At primary resistant strains occur almost secondary resistance. The mechanism of action is based on inhibition of bifonazole biological synthesis ergosterol at two levels, which significantly differentiates it from other antimycotics. When you double-action component of the fungal cytoplasmic membrane is damaged, not only at the structural level, but also at the functional.
Urea has keratoplastic effect increases the penetration bifonazole and softens the keratin sheath of the infected nail plate.
Urea potentiates the action bifonazole, increasing antifungal effect.
Pharmacodynamics and pharmacokinetics
Absorption with topical reaches 2-4%. In experiments on rats bifonazole active substance passes through the placental barrier. Systemic effects in the course of treatment are not registered.
Indications
Treatment onychomycosis .
Contraindications
Antifungal therapy bifonazole not carried out in pregnant women first trimester . The drug is contraindicated in individual hypersensitivity to the components.
Side effects
Mikospor rarely causes contact dermatitis , Desquamation, maceration, itch , Skin rash in the area of application of ointment.
Instructions for use (method and dosage)
Mikospor set polish is applied only topically. The ointment is applied to the entire surface of the infected nail with a thin layer of one time per day, gluing special patch from the set. It is recommended to apply a bandage on one day. After 24 hours, remove the patch and nail dipped in warm water. After 10 minutes, start to remove the softened layer infected by a fungal infection of the nail with a scraper from the set. Then nail dried again treated with ointment and glued tape. Treating nail adjacent to the skin is not recommended. When redness or irritation of the skin around the nail plate is recommended that pre-treatment of tissue adjacent zinc ointment.
The important point is regular and timely change of dressings. Treatment is carried out as long as the nail bed is smooth and the infected nail plate completely away from keratin material using the scraper. The average protivomikoticheskaya therapy lasts 1-2 weeks, depending on the thickness of the nail, the severity of the fungal disease. The drug has no effect on healthy tissue.
After complete removal of the nail treating doctor assesses the oniholizisa and the effectiveness of the therapy. In the absence of the expected effect of treatment continues cream mikospor for 4 weeks.
Overdose
The clinical picture in the medical literature is not described.
Cooperation
Importantly, no significant interactions described may mean low absorption of active ingredients in the systemic circulation.
Terms of sale
Over the counter.
Storage conditions
Tubes stored at a temperature no higher than 30 degrees.
Shelf life
Tubes can be stored for 3 years.
Cautions
In the event allergic responses on the plaster it is recommended to use special rubber fingertips or use a different type of adhesive. The effectiveness of antifungal therapy depends on the thoroughness of removal of the affected fungal infection of the nail plate layers.
Babies
At the moment there is not sufficient information about the safety of the drug in pediatric practice. However, clinical studies indicate no negative impact on children's health mikospor the treatment of onychomycosis.
Reviews mikospor set Nail (overview)
After analyzing users' messages on discussion forums, we can conclude that the medication is often prescribed by dermatologists to treat fungal infections. Patients leave only positive feedback, indicating a high efficacy in the treatment of mycotic lesions. Reviews mikospor Set in the treatment of nail fungus from the point to the good tolerability of the drug, even during prolonged treatment.
Price mikospor set nail where to buy
Pharmacies Moscow mikospor set price of 790 rubles.
No comments:
Post a Comment