Amiklon

Description overdue on 03/27/2013

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Antifungal medications.   The main ingredient -   clotrimazole . Large quantities of the active component acts fungicidally   (effect applies not only to the proliferating cells), small dosage drugs act fungistatically . The active ingredient is a derivative of imidazole , Applied vaginally, topically and locally. The mechanism of action is aimed at reducing synthesizing ergosterol Which it is a component of a microbial cell membrane which leads to a change in the structure and properties of the bacterial cell. The fungicidal amounts Amiklon affects peroxidase and mitochondrial enzymes that leads to increased levels of hydrogen peroxide to the concentration of toxic, harmful to the fungal cells. The drug acts on dermatophyte on gram-negative bacteria, pathogens on the multi-colored lichen on molds , Trichomonas on pathogens erythrasma on gram-positive flora, yeasts . Amiklon produced in the form of vaginal tablets, ointments, and cream powder. It is used only externally.

Indications:

Drug Usage Amiklon contains the following indications: fungal infections mucous membranes, fungal skin: microsporia , Athlete, trichophytosis, stomatitis , Ringworm, candidiasis Fungal paronychia, tinea, fungal interdigital erosion, with the accession of secondary fungal infections pyoderma . The drug is prescribed for erythrasma, balanitis, colorful shingles, vulvovaginitis, candidiasis vulva trichomoniasis , Pityriasis versicolor, for rehabilitation before delivery.

Contraindications:

Amiklon not indicated during menstruation, in case of intolerance clotrimazole, when carrying a pregnancy (first trimester). When breastfeeding medication used with caution (possible release of the active substance clotrimazole breast milk).

Side effect:

Amiklon may cause local reactions in the form puffiness , Peeling of skin, irritation, burning sensation, appearance blisters . erythematous rash   and paresthesias. Occasionally there is an allergic response in the form of urticaria and itching. Intravaginal use: swelling of the mucous membranes, they hyperemia, burning, itching, specific discharge from the vagina . intercurrent cystitis , Frequent urination, gastralgia, headache, pain during sexual intercourse, a burning sensation or burning sensation in the penis from a sexual partner.

Mode of application:

Amiklon used externally. Lotion, ointment, solution, and cream is applied to the affected area with a thin layer 2-3 times a day, perhaps massaging medicament neat, careful movements. A one-time amount of the drug in the region, an area of ​​palm - 10-20 drops of a solution or cream pancake bar to 0, 5 cm. The duration of treatment - 4 weeks. After the disappearance of clinical symptoms it is recommended to continue the use of the drug for 2-weeks. Treatment of multi-colored lichen   calculated for 1-3 weeks, erythrasma - 2-4 weeks. Stops before the procedure should be washed thoroughly with soap and water, wipe dry and grease preparation, carefully treating interdigital spaces. After reaching the therapeutic effect of the treatment of fungal infections continued for 2-3 weeks. Vaginal drug Amiklon form (gel and cream) are introduced into the vagina in portions of 5 grams of 1 times a day course is for 3 days. Treatment of Candida Balanitis and vulvitis:   preparation is used 2-3 times per day, the therapy is designed for 1-2 weeks. Vaginal tablets must be inserted deep into the vagina 100 mg for 6-7 days, or at 200 mg for 3 days or 500 mg single dose. Treatment should be combined with simultaneous processing of the external genitalia with a solution, cream or ointment. Permissible to re-treat. Remediation of the birth canal: clotrimazole administered once (1 tablet). Treatment of urethritis :   urethral instillation for 6 days with 1% clotrimazole.

Special instructions:

It requires the simultaneous treatment of all possible sex partners for prevention reinfection . Price Amiklon is 100-200 rubles (depending on the pharmacy network). The use of vaginal applicators during gestation pregnancy (2, 3 trimesters) is undesirable. Treatment trichomoniasis   It includes simultaneous reception of chemotherapy medications (oral metronidazole). Do not apply the special occlusive dressing after applying the cream Amiklon. Unacceptable ingress of medicament to the eye mucosa. Patients with liver disease need a mandatory control of enzymes ALT and AST. In case of irritation, allergic reactions, signs of hypersensitivity therapy is stopped. In the absence of positive dynamics during the 4 weeks of therapy Amiklon overturned.

Drug Interactions:

Amphotericin B and nystatin, natamycin and adversely affect the efficacy of therapy with simultaneous Amiklon.