Rinzasip

Description overdue on 09/11/2014

• Latin name: Rinzasip
• ATC code: N02BE71
• Active substance: Paracetamol + Caffeine + pheniramine + Phenylephrine (Paracetamol + Pheniramine + Caffeine + Phenylephrine)
• Manufacturer: Unique Pharmaceuticals Laboratories, India

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• Composition
• Product form
• Pharmacological action
• Pharmacodynamics and pharmacokinetics
• Indications
• Contraindications
• Side effects
• Instructions for use Rinzasipa (method and dosage)
• Overdose
• Cooperation
• Terms of sale
• Storage conditions
• Shelf life
• Cautions
• During pregnancy (and lactation)
• Reviews
• Price, where to buy

Composition

As part of the resources: 750 mg acetaminophen 20 mg maleate pheniramine 30 mg caffeine 10 mg phenylephrine hydrochloride . Also, the drug contains auxiliary elements:   citric acid, sodium citrate, Sunset Yellow FCF dye, orange flavor, sodium saccharin, sucrose .

Product form

The drug is produced in sachets of 5 grams. Each sachet is fine powder orange, white blotches are possible. Made from a slurry has the taste of orange, black currant and lemon.

Sachets are sold in packages made of cardboard, 5, 10, 25, 50 or 100 in each group.

Pharmacological action

Analgesic . vasoconstrictor . pyretic .

Pharmacodynamics and pharmacokinetics

The pharmacological activity of the drug is determined by the totality of its constituent materials.

Paracetamol   - analgesic, antipyretic It refers to the group anilides . It reduces the temperature painkillers. It shows weak anti-inflammatory activity. Compared with other substances in this group, paracetamol - low-toxic substance. The compound inhibits the synthesis of prostglantinov   by locking of both forms of the enzyme cyclooxygenase . It is also a means of selectively blocking TSOG3 (central nervous system), without affecting the TSOG1   and TSOG2 Which are located around the periphery.

Paracetamol   no adverse effects on GI It does not cause a delay Na + ions   in the body, disorders water-salt balance . The substance penetrates the blood-brain, placental   barrier absorbed in the small intestine. The degree of connection with plasma proteins is high enough, the maximum concentration observed in half an hour - an hour after entering the body.

Chlorpheniramine   - Heavy antihistamine   means being blocked H1 histamine receptors . The substance reduces the permeability of capillaries, relieves spasms in the bronchi, has anti-edematous activity. This weak sedative , Tends to reduce the intensity of mucus in the nasopharynx and bronchial tubes.

Caffeine   simulates central nervous system , Increases efficiency, both mental and physical. In combination with paracetamol   It accelerates absorption and enhances the effectiveness of the latter.

Phenylephrine hydrochloride   It is alpha-agonists . The substance constricts blood vessels, increases BP , Relieves swelling of the mucous membranes, reduces the pressure in the middle ear and sinuses. If the substance is used often and for a long time, then the body produces tolerance phenylephrine Requiring higher dosages.

Indications

The drug is prescribed for the symptomatic treatment ARI . Flu . SARS   and other cold diseases.

Contraindications

The drug is not prescribed:

• at pregnancy   and breast-feeding ;
• Children up to 15 years;
• when receiving any of the ingredients separately;
• at allergies   Substances belonging to the means.

Care should be taken:

• at atherosclerosis ;
• at elevated BP ;
• sick diabetes ;
• in the presence of blood diseases;
• liver or kidney disease;
• prostatic hyperplasia ;
• at asthma ;
• at thyrotoxicosis .

Side effects

FEATURES:

• sleep disturbances mydriasis . dizziness , Hyperexcitability;
• tachycardia   and increased Blood Pressure ;
• pain in the stomach, dry mucous membranes, nausea, disorders of the liver;
• abnormalities in the kidneys, difficult urination;
• hives . itch , Rash, syndrome of bronchial obstruction .

Instructions for use Rinzasipa (method and dosage)

Powder of one sachet dissolved in a large amount of hot water can be added sugar or honey taste.

Powder Rinzasip instructions for use advises to use as follows: daily dosage of up to 4 bags. The drug is taken every 4-6 hours after a meal. The duration of the assets - not more than 5 days.

Overdose

Overdose occurs mainly due to paracetamol , Part of the funds. When receiving more than 15 grams of the substance is observed pale skin, nausea, loss of appetite, vomiting. As therapy produce gastric lavage, enterosorbents , Elimination of unpleasant symptoms, 8 hours after overdose should take methionine At 12 - N-acetylcysteine .

Cooperation

When combined with the drug action ethanol , Sedatives and   MAO inhibitors   enhanced.

The probability of occurrence of adverse reactions of the drug is enhanced when combined with antidepressants . neuroleptics Derived phenothiazines . GCS . antiparkinsonian .

Effectiveness diuretics Taken together with the paracetamol It is significantly reduced.

When combined with guanetidinom   the hypotensive effect of the drug is reduced, increasing alpha adrenostimuliruyuschee   Rinzasip action.

Do not combine the drug with barbiturates . carbamazepine . inducers of microsomal liver enzymes . difeninom   due to increased load on the liver.

Terms of sale

Over the counter.

Storage conditions

Sasha kept unopened in a dry place at a temperature no higher than 30 degrees.

Shelf life

3 years.

Cautions

If 5 days after receiving the funds improvements in the state have not come, you should seek professional help.

In connection with the probability of occurrence of drowsiness and weakness, should refrain from the control mechanisms driving the vehicle at the time of ingestion.

During pregnancy and lactation

Because of the high toxicity and the ability to overcome the drug blood brain   and placenta , Its use during pregnancy lactation is contraindicated.

Reviews Rinzasipe

On the forums, there are many positive reviews about Rinzasipe. The drug is effective and is relatively inexpensive. Adverse reactions are rare, it helps to quickly get back on their feet. But do not forget that Rinzasip only eliminates the symptoms of the disease. Before taking advisable to consult a doctor.

Price Rinzasipa

Price Rinzasipa (box of 5 sachets inside) - 135 rubles.

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