Sanoksal

Description overdue on 03/27/2013

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Protivoprotozoynymi, anthelmintic . The main ingredient - Albendazole . The drug is actively used in poliinvazivnyh and monoinvazivnyh lesions. The main mechanism of the impact of is aimed at selective suppression of the polymerization process beta-tubulin, at suppressing glucose utilization, on the violation of activity of microtubular cell system in the intestinal channel of helminths, on blocking of movement secretory granules and other specific organelles in the muscle tissue roundworms That ultimately leads to the death of the parasite. High efficacy observed against Sanoksan   nematodes   and larval forms cestode . Sanoksan available in tablet dosage form (coated chewable forms) in the form of a slurry.

Indications:

Instructions for use of the drug Sanoksan recommended to prescribe the medicament when nematodoses   (giardiasis, ascariasis, enterobiasis, trichuriasis, strongyloidiasis, hookworm, opistorhoz, microsporidiosis) ehonokokkozah   lungs, liver, peritoneum, caused by Echinococcus granulosus (larval form of the dog tapeworm). The drug is prescribed for neurocysticercosis, caused by the larval form of Taenia solium (pork tapeworm). Sanoksan shown in mixed helminthiasis, and is also used as an auxiliary component in the surgical treatment of cysts ehinokokkoznyh.

Contraindications:

Sanoksan not prescribe intolerance alyuendazola, breast-feeding, if carrying a pregnancy and children up to the age of six.

Side effect:

The digestive tract:   increased rates of AST and ALT (liver enzymes), epigastric pain, vomiting, nausea . Nervous system:   meningeal signs, dizziness and headaches. Bodies of blood: pancytopenia   (devastation of the bone marrow), thrombocytopenia (lack of blood cells - platelets), granulocytopenia, leukopenia, agranulocytosis . On the background of treatment by a preparation Sanoksan probably rising of level of arterial pressure, the development of of alopecia, hyperthermia, of acute renal failure and violations of in the work of the renal system. Allergic reactions: itching, skin rash

Mode of application:

Sanoksal tablets taken orally, washed down with water, without chewing after meals. For young daily dosage makes 6 mg / kg, adult - 0, 4 grams. From the patient is not required to follow a special diet and the use of laxatives medicines. Treatment of ascariasis, enterobiasis, trichuriasis, hookworm:   a single dose of 0, 2 grams of Albendazole, a second reception is possible in three weeks if necessary. Treatment of children up to 2-uh years with the diagnosis «cysticercosis of the brain»: 8 days on the 15mg / kg / day. Treatment cestodosis and strongyloidiasis:   for 3 days daily take on 0, 2 grams of albendazole, repeated reception is possible after 3 weeks if required. Treatment for giardiasis:   for 3 days to take on 0, 4 grams daily albendazole.

Special instructions:

Women of reproductive age necessarily exclude the presence of pregnancy before prescribing medication Sanoksal. Patients with neyrotsistitserikozom   with the defeat of the eyeballs is a compulsory study of the retina (during treatment possible worsening of her condition). With leukopenia   therapy is stopped. It requires reliable contraception throughout the treatment period Albendazole. When taken in high doses it requires regular examination of liver function, control of blood parameters. Price Sanoksal preparation may vary depending on the pharmaceutical network (average 60 rubles).

Drug Interactions:

The concentration of the active drug substance Sanoksal increases with concurrent therapy cimetidine   and dexamethasone.