Teralidzhen

Description overdue on 05/22/2014

• Latin name: Teraligen
• ATC code: R06AD01
• Active substance: Alimemazine tartrate (Alimemazine Tartrate)
• Manufacturer: Pharmaceutical Joint Stock Company Hau Giang Province, Vietnam

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• Composition
• Product form
• Pharmacological action
• Pharmacodynamics and pharmacokinetics
• Indications
• Contraindications
• Side effects
• Instructions for use Teralidzhena (method and dosage)
• Overdose
• Cooperation
• Terms of sale
• Storage conditions
• Shelf life
• Cautions
• Analogs
• During pregnancy (and lactation)
• Reviews
• Price, where to buy

Composition

The structure 1 includes a 5 mg tablet   alimemazine tartrate . In addition, the composition contains the following auxiliary ingredients: colloidal silicon dioxide, lactose (milk sugar), talc, wheat starch, magnesium stearate, sucrose (sugar refined) tapioca.

Cover structure: talc, titanium dioxide, Valium, pink dye, macrogol 6000.

Product form

The medicine is available in tablets dark pink, film coated. On one side is a strip, on the other - embossed symbol.

Sold drug in outline packages, each package contains 10 or 25 tablets, in a carton box can be 1, 2, 5 packages.

Pharmacological action

Tablets have Teralidzhen antispasmodic . antiemetic . antihistamine . hypnotic . antitussive   and antipsychotic   action.

Pharmacodynamics and pharmacokinetics

Teralidzhen a neuroleptic (antipsychotic), providing serotoninblokiruyuschee . antispasmodic   and antihistamine action, as well as hypnotic . antiemetic . antitussive   and sedative   action.

Watch effect after administration can be within about 10-15 minutes, duration of action is 6 to 8 hours.

In the drug is low antipsychotic activity Therefore it is ineffective in the acute stage psychotic conditions .

It is used as therapy for the elderly, as children and adolescents, since the drug is well tolerated.

Completely absorbed quickly, observed maximum plasma concentration after administration may be 1-2 hours. Within 2 days excreted as metabolites kidneys (70-80%).

Indications

This medication is used to treat the following diseases:

• sleep disorders;
• senestopaticheskie depression ;
• in somatic diseases state of anxiety and unrest;
• psychopathy   with psihoastenicheskimi and asthenic disorders;
• somatized mental disorders;
• neuroses   and neurosis-like states   organic or endogenous origin with hypochondriac . psychovegetative . senestopaticheskimi   and phobic disorders ;
• allergic reactions ;
• anxiety-depressive illness   (Border and vascular diseases).

Contraindications

Teralidzhen has a number of contraindications:

• children up to 7 years;
• hypersensitivity to any drug ingredient;
• myasthenia ;
• pregnancy ;
• prostatic hyperplasia ;
• reception MAO inhibitors ;
• lactation ;
• Parkinsonism ;
• angle-closure glaucoma;
• Reye's syndrome ;
• kidney and liver (severe stage).

Administration of the drug be used with caution in the following cases: suppression of bone marrow function . epilepsy . hypotension , Chronic alcoholism, jaundice Predisposition to urinary retention, open-angle glaucoma . bladder neck obstruction .

Side effects

Tablets Teralidzhen are well tolerated and rarely cause the occurrence of side effects.

The following side effects:

• tachycardia . pressure decrease . dizziness ;
• paresis of accommodation Ringing, ringing in the ears;
• increased viscosity of bronchial secretions, dry throat, nose;
• lethargy, drowsiness, fatigue (these symptoms usually occur within the first few days, do not require discontinuation of the drug), nightmares, anxiety, irritability, agitation; In rare cases, it may be observed hypokinesia , Confusion, tremor . akathisia In children - increased seizure activity;
• urinary retention, atonic bladder ;
• loss of appetite, constipation , Atonic gastrointestinal tract, dry mouth;
• muscle relaxation , Inhibition of hematopoiesis in bone marrow, photosensitization , Allergic reactions, increased sweating.

Instructions for use Teralidzhena (method and dosage)

The tablets are intended for ingestion.

For getting hypnotic effect   per night for adults need to take 5-10 mg, anxiolytic effect   - 60-80 mg, with psychotic state   - 0, 2-0, 4 g

Instructions on Tiralidzhen for children (over 7 years) in order to achieve hypnotic effect   - 2, 5-5 mg anxiolytic effect   - 20-40 mg in the treatment of allergic reactions   - 5-20 mg. The daily dose psychotic conditions and can be increased to 60 mg.

The daily dose should be distributed on 3-4 receptions.

Overdose

If overdose occurs depression of consciousness As well as potentiation of side effects.

Since there is no specific antidote It applies symptomatic treatment. Within an hour after taking high doses of Teralidzhena necessary to wash out the stomach and assign enterosorbentnye means (to reduce absorption alimemazine ).

Cooperation

The drug can be enhanced anxiolytic . hypnotics . antipsychotic means analgesic drug . means general anesthesia . antihypertensive drugs   and Mr. holinoblokatorov . In such cases it is necessary to adjust the dose.

Teralidzhen reduce effectiveness of Mr. holinostimulyatorov . Dopamine . ephedrine . amphetamine . levodopa . guanetidina . Significant CNS depression is observed at the same time taking with medications that suppress the central nervous system and ethanol . Combination with barbiturates and antiepileptic drugs   It reduces the threshold of convulsive readiness.

Increased plasma concentrations cause alimemazine beta-blockers That can lead to Arrhythmia   and pressure reduction.

Teralidzhen contributes to raising prolactin   in the blood and decreases the efficiency bromocriptine .

M-anticholinergic activity alimemazine increases during reception antiholinegicheskih funds   and tricyclic antidepressants .

The risk of extrapyramidal disorders   and hypotension   increases when receiving MAO inhibitors   and phenothiazine derivatives .

Terms of sale

Buy Teralidzhen in the pharmacy can be strictly on prescription.

Storage conditions

Tablets should be stored in a dark place at a temperature not exceeding 25 ° C.

Shelf life

The drug should be kept for 3 years.

Cautions

In cases where you need long-term therapy, liver function should be assessed and continuously analyze the blood.

Before the drug increases the need for riboflavin .

During therapy, a pregnancy test may give a positive result.

During treatment should not get behind the wheel of a vehicle or engage in work that requires quick reaction and concentration.

Analogs Teralidzhena

Currently Known analogs of this drug: Rispolept . Seroquel . Alimemazine tartrate .

During pregnancy and lactation

Tablets are absolutely contraindicated for use during pregnancy. If necessary dose, you must stop breast-feeding.

Reviews Teralidzhene

Overall score set by buyers in the forums - 3, 8 of 5 points. Many patients write about the effectiveness of the drug, its fast action and no side effects. In addition, there are customer reviews, which the drug has not helped, as many write the strong manifestation of side effects such as fatigue, drowsiness, dizziness. With regard to its use in children, the reviews are positive. For children, it is safe because it is very well tolerated.

Doctors about Teralidzhene positive, however, they say that you can not take the drug without prescription, since because of this the patient can only get worse.

The encyclopedia Wikipedia information about this medicinal product no.

Price Teralidzhena

In Russia, the average price per pack of 25 tablets - 282 rubles, 50 tablets - 465 rubles.

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