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Anthelminthics . It is based on the neuromuscular blocking parasites that allows to expel the worms without stimulation and excitement migration. In the lumen of the intestinal tract drug effective against helminths both sexes (mature and immature forms). Pyrantel is effective against hookworms, ascarids, pinworms, pathogens trichuriasis . With regard whipworm indicated moderate activity. Pyrantel is produced in the form of suspensions, tablets.
Indications and contraindications:
Pyrantel prescribed for enterobioze , Ascariasis, trihotsefaleze , Necatoriasis, hookworm . The drug is not used during the treatment period myasthenia , Intolerance of components. In pediatrics, pathology, hepatic system, breastfeeding, pregnancy Pyrantel prescribed with caution, after careful examination and evaluation of the importance of treatment.
Side effect:
Pyrantel can cause diarrhea, vomiting, headaches, loss of appetite, sleep disturbances (drowsiness or insomnia), dizziness, nausea, hallucinations , Auditory perception disorders, hepatic enzyme elevations system hyperthermia . paresthesia , Confusion.
Mode of application:
Enterobiasis, ascariasis mixed infestation : Once after breakfast take Pyrantel is based circuit 10 mg 1 kg of weight. When body weight greater than 75 kg administered 1 gram of anthelmintic agent. To prevent samoinvazii repeat the course in 3 weeks after the first dose. The combination with nekaratozom ascariasis, hookworm Pyrantel treat drug intake for three days according to the scheme 10 mg / kg / day or take 20 mg / kg / day for two days. When isolated form ascaridosis drug taking a single dose of 5 mg / kg. It is recommended to chew the tablet before swallowing.
Special instructions:
Treatment involves performing enterobiasis anthelmintic treatment of all contacted relatives. After administration of the drug is not administered laxative. After the treatment is necessary to examine the feces on helminth eggs. Pyrantel is considered more effective in treating 12- hookworm versus American hookworm . Prevention reinfection It is clean clothes and cleaning.
Drug Interactions:
It is unacceptable at a time with the drug appoint Pyrantel piperazine (weaken the effectiveness of each other). The drug is able to increase the level of theophylline in blood.
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