Description overdue on 09/12/2014
- Latin name: Penzital
- ATC code: A09AA02
- Active substance: Pancreatin (Pancreatin)
- Manufacturer: Shreya Life Saensiz Pvt. Ltd., India.
- Composition
- Product form
- Pharmacological action
- Pharmacodynamics and pharmacokinetics
- Indications Penzitala
- Contraindications
- During pregnancy (and lactation)
- Side effects
- Penzital - application instructions (method and dosage)
- Overdose
- Cooperation
- Cautions
- Terms of sale
- Storage conditions
- Shelf life
- Analogs
- With alcohol
- Reviews
- Price, where to buy
Composition
Penzital tablet contains: Active ingredient - Pancreatin And auxiliary substances: lactose, MCC, povidone, sodium starch glycolate, diethyl phthalate, talc, aerosil, titanium dioxide and Methacrylic acid copolymer . Wherein Pancreatin It has the following enzymatic activity (U FIP): lipase - 6000; amylase - 4500; Protease - 300.
Product form
Penzital Available in tablet form, which are offered in packaging of 100, 30 and 20 pieces per pack.
Pharmacological action
The drug has lipolytic, amylolytic, proteolytic the action of filling shortage of enzymes pancreas.
Pharmacodynamics and pharmacokinetics
Receiving this medication to compensate for lack of external secretory function in pancreas . This has proteolytic, amylolytic and lipolytic effect.
Enzymes Which are part of the Pancreatin , namely - lipase, alpha-amylase, chymotrypsin and trypsin helps cleave proteins to amino acids, fats into fatty acids and glycerol, starch and dextrins to monosaccharides. Also improves the functional state of the stomach, normalize the digestive process.
Due trypsin inhibited stimulated pancreatic secretion, producing an analgesic effect.
In an alkaline environment in the small intestine from the dosage form pancreatic enzymes are released, because they have a protection against the influence of gastric juice in the form of a shell.
Manifestation of the maximum enzyme activity occurs after 30-45 minutes after oral administration. Suction pancreatin in the gastrointestinal tract does not occur, the substance derived with feces.
Indications Penzitala
The main indications for use:
- holding substitutive treatment of exocrine insufficiency of the pancreas, for example, chronic pancreatitis, pancreatectomy , After the state dyspepsia . exposure . syndrome Remhelda or gastrocardiac syndrome, cystic fibrosis;
- diarrhea non-infectious origin, flatulence ;
- malabsorption of food, for example, after resection of the small intestine, and stomach;
- the need to improve food digestion in people who have normal function of the gastrointestinal tract in the nutritional errors - large amounts of food, fatty foods, irregular meals, as well as violations of the chewing function, sedentary lifestyle and prolonged immobilization;
- carrying out preparations for X-ray examination and ultrasound of internal organs.
Contraindications
Do not take Penzital at:
- hypersensitivity to the drug;
- acute pancreatitis;
- exacerbation of chronic pancreatitis.
Use in pregnancy
Capable of receiving during Penzitala pregnancy If it is really necessary for the mother. This should maximize the benefits outweigh the risks for the future child.
Side effects
When treating Penzitalom may arise undesirable effects, mainly in the form allergic reactions . Individual cases are accompanied by: diarrhea, constipation, discomfort, nausea and so on.
Penzital - application instructions (method and dosage)
Tablets are designed to receive inside And apply them better before meals . This zapivaniya suitable for ordinary water. Contraindicated for use for this purpose alkaline liquid.
According to the instructions for use Penzitala, dose selection is performed by a gastroenterologist, which should take into account the dietary habits of the patient and the degree of enzyme deficiency. The average daily dosage for adults is: 1-2 tablets 3 times . Avoid elevated daily dosage of 16 tablets.
In the treatment of young patients, dose selection is performed individually.
The course of treatment is established by the attending physician and can last for several years.
Overdose
In overdose pancreatin may occur:
- hyperuricosuria;
- hyperuricemia;
- constipation - Mostly in young patients.
Complex cases require discontinuation of the drug overdoses, lavage of the stomach and intestines, the appointment of symptomatic treatment.
Cooperation
Simultaneous use and Penzitala antacids ions of aluminum, calcium or magnesium can substantially reduce its effect. Iron preparations can reduce the absorption of iron.
Combination therapy with this tool antithrombotic drugs and acetylsalicylic acid reduces their effectiveness.
When treatment is given in conjunction with non-selective monoamine reuptake inhibitors, we can expect the development of a dangerous lethargy, M-holinoblokatorami was an increase in anticholinergic action, and alkaline liquid violate pharmacodynamics Penzitala.
Cautions
Diseases such as cystic fibrosis Require the use of pancreatin in moderate doses, because it may increase the risk of fibrotic strictures or colonopathy. Therefore, the dose administered strictly on the number of enzymes required for fat absorption, considering the quality and quantity of food consumed. As a rule, long-term treatment is accompanied by a simultaneous appointment of iron-containing preparations.
Terms of sale
In pharmacies pills without a prescription.
Storage conditions
The medicine should be stored in a cool, dry place, protected from children.
Shelf life
3 years.
Analogs
Mikrazim
Enzistal P
Pancreatin
Pangrol
Ermital Creon
Abomin
Festal
Mezim
General preparation of analogs represented by means such as: Gastenorm Forte, Creon, Mezim, Mikrazim, Pangrol 10000 Panzica, Panzinorm, Panzi Forte and others.
Also, drugs with similar action are: Pancrelipase, pantsitrat Festal, enzistal-P Ermital and so on.
Alcohol
It is known that alcohol is a precipitating factor for the development of disorders in which appointed Penzital. Therefore, during treatment of alcohol is recommended to abstain.
Reviews Penzitale
This drug is very popular not only in patients suffering from various diseases of the gastrointestinal tract, but also in need of medication from overeating. Therefore, reviews of Penzitale ubiquitous.
Often this means is indicated for pregnancy Since during this time it may need to have an effect quickly, which causes almost no side effects. For example, it is actively used by women who feel a strong after eating heaviness in the stomach or nausea .
Furthermore, this group of patients the drug can be assigned to improve digestion and normalize the functions of the digestive tract. Although many women do not even know exactly from what Penzital help during pregnancy. So often there are detailed explanations of specialists who tell from what pills help Penzital best as and when they need to take.
In general, as shown by the reviews, this drug is quite effective. However, despite the fact that it is an enzyme, and according to some safe for the body to take it without a prescription is not recommended.
Price Penzitala where to buy
This drug tablets, enteric-coated, can be purchased at any Russian pharmacy. The price Penzitala 20 pieces can range 51-60 rubles.
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