Description overdue on 12/11/2014
- Latin name: Oftan Catachrom
- ATC code: S01XA
- Active substance: Nicotinamide Adenosine + + Cytochrome C (Nicotinamide + Adenosine + Cytochrom C)
- Manufacturer: Santen AO, Russia
- Composition
- Product form
- Pharmacological action
- Pharmacodynamics and pharmacokinetics
- Indications
- Contraindications
- Side effects
- Eye drops Oftan Katahrom, instructions (method and dosage)
- Overdose
- Cooperation
- Terms of sale
- Storage conditions
- Shelf life
- Cautions
- Analogs
- During pregnancy (and lactation)
- Reviews
- Price, where to buy
Composition
Eyedrops Oftan Katahrom contain (per 1 ml): 20 mg nicotinamide 0, 675 mg Cytochrome C 2 mg adenosine + Additional ingredients ( sodium succinate hexahydrate, disodium 2-phosphate aqueous solution, water, benzalkonium chloride, sorbitol, sodium dihydrogen phosphate aqueous two- ).
Product form
The drug release in bottles made of plastic, with a dropper, a volume of 10 ml. The drug - a clear red solution. The cardboard package is a bottle.
Pharmacological action
The anti-inflammatory, antioxidant, nourishing .
Pharmacodynamics and pharmacokinetics
The therapeutic effect of receiving the plurality of droplets is caused, their constituent substances.
Cytochrome C neutralizes free radicals on the cornea. The substance is also directly affects the crystal eyes, reducing the risk of Cataract (inhibiting the synthesis of the enzyme cytochrome oxidase ). This component is split in the epithelium to the crystallite heme-peptide .
Adenosine dilates blood vessels and helps to restore normal microcirculation in the eye. Also normal outflow toxins and blood oxygen saturation. Substance suspends inflammatory process at conjunctiva . cornea and anterior eye , By stimulating A2 receptor on the surface of cell membranes. Note that adenosine It is one of the fundamental elements in the process of renovation DNA and energy metabolism. As a structural component of the enzyme glutathione reductase and NADP , The substance acts as an intermediary in the process of recovery glutathione Occurring in the crystallite eyes.
Nicotinamide a part of the NADP and ABOVE - Major metabolites crystal of the eye. It is supposed to reduce the rate of development Cataract by increasing the amount of metabolites.
Due to the fact that the drug has low toxicity can be used as prophylaxis for suspending Cataract . The duration of treatment should be at least six months.
The drug affects not only the crystal. We prove that the vehicle has anti-inflammatory . antioxidant . Disinfectant and Antibacterial effect on the surface of the eye, can stop the development of various infectious diseases in the anterior eye. Also, the drug is well moisturizes and relieves fatigue.
Cytochrome C systemic absorption is not exposed. Once in the body full metabolized before bilirubin Which in turn is derived from bile.
Adenosine It has the ability to penetrate deep into the cornea of the eye, and distributed to all tissues. The tissues of the body very quickly (in minutes) the substance is transformed into inosine, urate and xanthine That are excreted through the kidneys.
Nicotinamide rapidly absorbed, some of it is metabolized to nicotinic acid And then to N-methylnicotinamide . Both compounds are excreted by the kidneys.
Indications
Drops is indicated for the prevention and treatment Cataract of different origin.
Contraindications
Receiving money is contraindicated in allergies on any of the components of the drug for children and adolescents (those under 18).
Side effects
Immediately after instillation may furnace or felt tingling in his eyes.
FEATURES:
- allergic reactions ( conjunctivitis , Itching, contact dermatitis );
- rashes and itching on the skin, hyperemia , Swelling of the face and skin.
Very rarely can be observed:
- nausea, unconsciousness, shortness of breath;
- pressure reduction, flushing, feeling of fever, weakness.
Eye drops Oftan Katahrom, instructions (method and dosage)
The drug is used only locally.
Before use, cover the vial should be rotated while pressing down, open the bottle.
It is necessary to carefully push the lower eyelid, look up and drip the medicine under the lower eyelid.
According to the instructions, appoint 1-2 drops, 3 times a day.
Course duration is usually determined by the attending physician. The course of treatment should be at least 6 months.
Overdose
No cases of overdose have been reported.
Due to a minor system Absorption and the rapid removal of the means at its ophthalmic use, overdose is unlikely.
If the drug was accidentally ingested, it should be symptomatic therapy.
Cooperation
Drug interactions of the drug with other agents does not occur or was not observed.
Observe the 15-minute break between the use of a variety of ophthalmic equipment.
Terms of sale
Prescription.
Storage conditions
Keep the vial should be at a temperature of 8 to 15 degrees.
Shelf life
3 years. After first opening the vial, the shelf life is reduced to 30 days.
Cautions
Before using the drops, remove contact lenses and wear them for 15 minutes in order to avoid penetration of benzalkonium chloride in the lens.
The drug is not intended for oral administration, or as injections.
The drug should not be used by patients glaucoma .
To avoid contamination of the tip of the bottle they can not touch the skin or mucous membrane of the eye.
After receiving means possible short-term blurred vision.
Analogs
Taufon
Oftagel
Retinalamin
Korneregel
Vizomitin
Kvinaks
Vidisik
Thiotriazoline
The most common counterparts: Artelak, Vidisik Artificial tears Kvinaks, Lipoflavon, Okoferon, Oftagel, Oftalmosol, Restasis, Solkoseril, Taufon, Thiotriazoline, Zhetrea, Potassium Iodide, Korneregel, Optive, Sikapos .
During pregnancy and lactation
There is insufficient clinical data on the use of means of pregnant or nursing women. In this regard, the application of drops is not recommended.
Reviews Oftan Katahrom
Reviews of eye drops Oftan Katahrom good. The drug stabilizes the lens of the eye does not develop cataract ; It worked well as a prophylactic. Adverse reactions are extremely rare.
Price Oftan Katahrom
Price eyedrops Oftan Katahrom is about 190 rubles per bottle 10 ml.
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