Description overdue on 07/28/2014
- Latin name: Septolete Plus
- ATC code: R02AA
- Active substance: Benzocaine + cetylpyridinium chloride (Benzocaine + Cetylpyridinium chloride)
- Manufacturer: KRKA (Slovenia)
- Composition
- Product form
- Pharmacological action
- Pharmacodynamics and pharmacokinetics
- Indications
- Contraindications
- Side effects
- Instructions for use Septolete Plus
- Overdose
- Cooperation
- Terms of sale
- Storage conditions
- Shelf life
- Reviews
- Price, where to buy
Composition
Pastilles and spray Septolete Plus contain as active substances benzocaine and cetylpyridinium chloride .
Adjuvants in Spray: ethanol . saccharin sodium , Water, glycerin, peppermint oil.
Other ingredients in the lozenge: levomenthol, flavor lime, maltitol liquid, glycerol, colloidal silicon dioxide, Kapolei 600 Pharma, titanium dioxide, maltitol, oil of peppermint leaves, flavoring honey, mannitol, castor oil, magnesium stearate, povidone, coloring quinoline yellow E104 , caramel coloring E150a, E129 red dye.
Product form
Septolete Plus is available as a spray and pastilles smooth surface (sheath dark yellow color).
Pharmacological action
The drug for use in diseases of the throat, antiseptic effect.
Pharmacodynamics and pharmacokinetics
This drug has Antimicrobial . Valium and antimycotic action Which is due to the properties of its active substance - cetylpyridinium chloride and benzocaine .
Cetylpyridinium chloride - Active antiseptic with anti-viral, anti-fungal and anti-microbial action. Mainly it acts on Gram-positive bacteria.
Benzocaine - Mestnoanestiziruyuschy component that reduces pain in the throat. It blocks the conduction of nerve pain impulses by reducing the permeability of cell membranes to sodium ions.
Pastilles Septolete Plus Inter alia, contain polyols : mannitol . maltitol etc., which improve the antiseptic and the anesthetic activity of the drug.
Regarding the pharmacokinetic data about cetylpyridinium chloride no. Information about the pharmacokinetics benzocaine It is also very limited. It is known that it is poorly soluble in water and therefore its absorption is small. It is hydrolyzed by cholinesterase in the blood plasma and a small amount is metabolized in the liver. Excreted in the urine.
Indications
Take this remedy should be for diseases of the throat and mouth:
- pharyngitis ;
- initial step sore throat ;
- laryngitis ;
- inflammations ( g ingivit . stomatitis ).
Contraindications
Do not take the medicine if:
- increased sensitivity to one or more components of the formulation;
- alcohol abuse;
- Children under 6 years of age;
- hypersensitivity to other local anesthetic;
- methemoglobinemia .
Side effects
Unwanted side effects when used Septolete Plus are very rare, if you follow the recommended dosage. Occurrence allergies , and nausea and diarrhea . In this use of the drug should be discontinued immediately.
Instructions for use Septolete Plus
If you have purchased spray , Instructions on Septolete Plus provides the following dosages:
- Adults and children from 12 years: 2 pressed every 2-3 hr., but not more than 8 times a day;
- children from 6 to 12 years old: one push every 2-3 hours, but not more than 8 times a day (only under adult supervision).
This spray should not be used for more than 7 consecutive days.
Before first use, means or if it has not been used for a long time, remove the plastic cover and press the atomizer head 5-9 times, producing a small stream in the air until you get the normal spraying.
When you try to disclose further use of his mouth as wide as possible, the head of the spray gun is directed to the throat. When spraying, hold your breath. After that, be sure to close the lens cover spray.
The spray is intended strictly for personal use.
Instructions for use Septolete Plus as pastilles It provides the following dosages:
- adults and children aged over 12 years - one lozenge every 2-3 hours., but not more than 8 units per day;
- children from 6 to 12 years old - one lozenge every 4 h., but not more than 4 units per day.
Do not combine the medication with milk or use it immediately before a meal.
Overdose
Overdose or prolonged use may lead to methemoglobinemia . Its symptoms may occur after about 45-60 minutes after the overdose. This can be headache , Fatigue, breathlessness . cyanosis . asthenia , Palpitations, arrhythmia . convulsions .
At very high doses may be nausea, vomiting, or even coma .
If signs of intoxication use of the drug should be discontinued.
Treatment involves administering 100% oxygen or gastric lavage, activated charcoal, maintaining breathing and circulation in severe cases.
Cooperation
Contained in a preparation benzocaine reduces the antibacterial activity sulfonamides .
Also, its effect can be enhanced nenarkoticheskimi analgesics and cholinesterase inhibitors .
Terms of sale
In pharmacies, the medicine is available without prescription.
Storage conditions
Keep Septolete Plus you need out of the reach of children and well-protected from light and moisture at a temperature not greater than 25 ° C.
Shelf life
Shelf life in compliance with all the conditions of storage is 2 years.
Reviews
Reviews of this medicinal product is mainly positive. It is very pleasant to the taste and good relieves pain in the throat. Some, however, complain of very short-term effect and the presence of dyes.
Price Septolete Plus, where to buy
Price Plus Septolete average 150 rubles. This is a medicine in Ukraine can be bought for 70 UAH.
No comments:
Post a Comment