Pyracetam

Description overdue on 09.11.2011

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Nootropics. Piracetam positive effect on metabolic processes in the brain (GM) and increases the production of phospholipid synthesis, RNA, increases the level of ATP in the brain tissue stimulates glycolysis It enhances glucose utilization. Piracetam helps to consolidate the processes of memory, stimulates brain integrative activity, facilitates the learning process. Piracetam increases the speed of conduction of excitation in the brain that inhibits platelet aggregation active improves microcirculation , But it does not narrow the vessel lumen.

If damaged brain tissue electroshock . intoxication . hypoxia   Piracetam has a protective effect: reduces the severity vestibular nystagmus It reduces delta activity, increases alpha and beta activity in the EEG. Under the influence of piracetam improves synaptic conductivity in the neocortical regions of the connection between the hemispheres, cerebral blood flow It increases mental performance. Piratsetm has no psychostimulant, sedative action. The effect over time.

Indications:

Piracetam is prescribed for neurological disorders: chronic cerebrovascular insufficiency   (headaches, impaired speech, memory, attention), GM's disease, the consequences of ischemic stroke, and coma subkomatoznye (intoxication, traumatic injuries GM), convalescence (to improve mental, motor activity) Alzheimer's disease . The Piracetam is prescribed for mental health astenodepressivnyh syndrome . neurotic syndrome Defective vyaloapaticheskih states ( psycho-organic syndrome . schizophrenia ). The drug is effective in the treatment of depressive states, cortical myoclonus Resistance, antidepressants, antipsychotics intolerance. The Addiction piracetam treated: delirious state, alcohol withdrawal syndrome of morphine abstinence symptom , Acute poisoning by barbiturates, ethanol, fenaminom, morphine, chronic alcoholism. The drug is effective in the treatment of sickle-cell anemia combined. In pediatrics Piracetam is prescribed to eliminate the effects of perinatal brain injury (birth trauma, intrauterine infections, hypoxia), and Cerebral Palsy . mental retardation , Mental retardation.

Contraindications:

Haemorrhagic stroke . allergy   into components, severe renal insufficiency system (CC less than 20 ml / min). Be wary of extensive surgical interventions, violation of hemostasis Heavy bleeding during pregnancy.

Side effect:

The motor disinhibition, hyperphrenia , Poor concentration, mental instability, irritability, stomachalgia , Loss of appetite, sleep disturbances, extrapyramidal disorders , Dizziness, tremor , Deterioration in the current angina , Dyspepsia, convulsions, increased sexual activity. Side effects of the drug Piracetam appears most often in the appointment of more than 5 grams per day.

Mode of application:

Piracetam is administered intravenously and inside. Starting dose / introduction is 10 mg, in severe cases, permitted the introduction of up to 12 mg per day for 30 minutes. The tablet form: three cycles of 800 mg, with improving the overall dosage is reduced to 400 mg, treatment and 8 weeks. A second course of treatment may be performed after 8 weeks. Cortical myoclonus: initial dose - 7, 2 g per day, then every four days the dose is increased by 4, 8 grams per day until reaching the maximum dose - 24 mg three times a day. Then, every six months, reduce the dose every two days 1, 2 g. Vertigo: 4, 8 g three times a day. Sickle cell disease: 160 mg per 1 kg in 4 receptions. Dosage for children: 30-50 mg per day.

Overdose:

When receiving a 75 mg piracetam marked dyspepsia. Recommended hemodialysis. No antidote.

Special instructions:

During treatment requires regular and close monitoring of renal and hepatic systems. If necessary, treatment can be combined with cardiovascular and psychoactive drugs. Complex treatment of acute lesions in addition to the GM pyracetam includes specific methods of rehabilitation, detoxification therapy. In patients with cortical myoclonia   not recommended abrupt discontinuation of medication to prevent attacks. Perhaps sleep disturbances, in this case, an evening dose combined with daily. Reduces the rate of reaction.

Drug Interactions:

Together with the admission neuroleptics   reducing the likelihood of extrapyramidal disorders. Piracetam increases the effective action of antipsychotic drugs, anticoagulants , Thyroid hormones.