Description overdue on 05/15/2014
- Latin name: Vero-Tamoxifen
- ATC code: L02BA01
- Active substance: Tamoxifen (Tamoxifen)
- Manufacturer: OAO Veropharm, Russia
- Composition
- Product form
- Pharmacological action
- Pharmacodynamics and pharmacokinetics
- Indications Vero Tamoxifen
- Contraindications
- Side effects
- Instructions for use of Vero-Tamoxifen (method and dosage)
- Overdose
- Cooperation
- Terms of sale
- Storage conditions
- Shelf life
- Analogs
- Reviews
- Price, where to buy
Composition
There are two types of dosages Vero Tamoxifen:
- per tablet active substance ( Tamoxifen ) 10 mg;
- per tablet Tamoxifen 20 mg.
Product form
Tablets contained in the contour packs of 10 units each. Packaging carton 10, 30, 50 and 100 pieces or glass jars with the same amount of drug.
Pharmacological action
The antitumor agent.
Pharmacodynamics and pharmacokinetics
The active substance inhibits the process of developing estrogen , Impact, mainly on target organs . Thus there is a slowdown in the development process tumor .
The drug is metabolized in the liver property. The output of waste substances ( N-dezmetiltamoksifena and 4-hydroxy tamoxifen ) Is produced mainly through GI (with stool).
Indications Vero Tamoxifen
The drug is indicated for the treatment of cancer, different etymology:
- mammary cancer at Menopause in women and after Castration men;
- ovarian cancer and prostate ;
- renal cancer ;
- melanoma , Sensitivity in use Tamoxifen .
Contraindications
The drug is not prescribed for pregnant and breast, thrombophlebitis . drug allergy into its components.
Side effects
- nausea, cholestasis, hepatitis, vomiting ;
- thrombocytopenia, leukopenia ;
- depression . Bad mood . dizziness, headache, ;
- edema, phlebitis ;
- bleeding from the vagina;
- allergic reactions skin;
- fever, tides . vaginal bleeding ;
- cataract , changes in Retinal , Blurred vision.
Instructions for use of Vero-Tamoxifen (method and dosage)
Assign dosage and rate of drug administration must physician, depending on the extent and severity of the disease.
The daily dose is 20-30 mg, it is divided into 2 doses. The treatment takes place before the occurrence of the positive or negative changes in the analysis.
Overdose
No cases of drug overdose. However, when it occurs most likely increased side effects. Treatment - according to exhibited symptoms.
Cooperation
At the same time taking pills that increase pH in the stomach to be observed interval of 2 hours between the two drugs.
Combination with cytostatics It increases the likelihood of blood clots .
With combined with caution warfarin and a number of other means coumarin .
Preparations containing estrogen Reduce the effectiveness of Vero-Tamoxifen.
Terms of sale
As with the purchase of other antineoplastic agents, require a prescription.
Storage conditions
Do not give into the hands of children. Store in a cool, dry place.
Shelf life
2 years.
Analogs
Tamoxifen-health fazlodeks, Tamoxifen Ebewe, FARESTON, zitazonium .
Reviews for Vero Tamoxifen
Reviews are positive. The drug is actively used for the prevention relapse After surgical interventions in malignancies . Basically it complains hard tolerable side effects. As a rule, after six months of taking the drug the body gets used and discomfort goes away. Some read that foreign-made drug is less toxic.
Price (Where to buy)
The price of the drug is about 60 rubles 30 tablets of 10 mg, $ 100 for the same amount of 20 mg.
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