Penicillin

Description overdue on 17.12.2011

Related Articles:

• Augmentin 875
• Buy Neo Pilobakt
• Nimulid, instructions for use
• Nervohel: reviews and price

Tweet

An antibiotic is a natural (biosynthetic) penicillin. It has bactericidal effects. The principle of operation is based on inhibition of bacterial cell wall synthesis. Affects   staphylococci . pneumococci , Anthrax bacillus, Corynebacterium diphtheria, anaerobic spore-forming bacillus, neisserial, gonorrhea, spirochetes, meningococcus . No effect on protozoa, viruses, rickettsiae. Benzylpenicillin is unstable in an acidic environment being destroyed. Available as a powder for solution.

Indications:

Penicillin antibiotic therapy prescribed for focal pneumonia, lobar pneumonia, bronchitis . bacterial endocarditis , Sepsis, pleural empyema, osteomyelitis . meningitis , Peritonitis, cystitis . gonorrhea , Pyelitis, ophthalmia, pyelonephritis . cervicitis . syphilis . otitis . cholecystitis Impetigo, erysipelas, cholangitis . Diphtheria , Actinomycosis, anthrax, scarlet fever . sinusitis , Eye diseases.

Contraindications:

Penicillin is not prescribed for hyperkalemia epilepsy , Arrhythmias, pregnancy, breastfeeding.

Side effect:

Endolyumbalno introduction: convulsions, meningeal symptoms, increased reflex excitability, vomiting, neurotoxic reactions . Potassium salt: hyperkalemia, cardiac arrest, arrhythmia. Sodium salt: reduced cardiac pump function. Rarely recorded anaphylactic shock. Perhaps the development of hives , Arthralgia, bronchospasm, interstitial nephritis , Eosinophilia, hyperthermia.

Mode of application:

Benzylpenicillin sodium salt administered pozhkozhno, endolyumbalno, intramuscular, intravenous, intratracheal. Moderate forms of infections: 4-6 million units per day, divided into 4 doses. Severe: 10-20 million units per day. In the treatment of gas gangrene appoint 40-60 million units per day. When purulent diseases of the meninges, spinal cord, brain Penicillin is administered endolyumbalno: 5-10 thousand units per day, treatment 3 days, then move on to the injection. The potassium salt of benzylpenicillin administered alone subcutaneously, intramuscularly. Procaine penicillin G is administered only intramuscularly. The average dosage of the drug for adults is 300 thousand units once, per day - 600 thousand units. The course of treatment lasts on average 7-10 days.

Special instructions:

In intramuscular solutions must be prepared ex tempore. In treatment failure within three days of antibiotic therapy, a requirement for a combination therapy, the change of the antibiotic. Long-term treatment for the prevention of fungal infections appoint ascorbic acid, B vitamins, levorin, Nystatin . To prevent the development of resistant strains is recommended that the dose assigned to a course of treatment.

Drug Interactions:

Tetracyclines, lincosamides, chloramphenicol , Macrolides and other bacteriostatic antibiotics cause antagonistic effect. Aminoglycosides . rifampicin Cephalosporins are sinnergicheski with the drug Penicillin. Indirect anticoagulants   enhance its effect. Penicillin reduces the reliability of oral contraceptives lowers prothrombin index It suppresses intestinal flora. Phenylbutazone, allopurinol Diuretics increase the concentration of the drug. Allopurinol in combination with benzylpenicillin results in the development of skin rash.