Description overdue on 09/16/2014
- Latin name: Magnesium orotate
- ATC code: A12CC09
- Active substance: Orotic acid (Orotic acid)
- Manufacturer: PIC-PHARMA LTD (Russia)
- Composition
- Product form
- Pharmacological action
- Pharmacokinetics and pharmacodynamics
- Indications
- Contraindications
- Side effects
- Instructions for use (method and dosage)
- Overdose
- Cooperation
- Terms of sale
- Storage conditions
- Shelf life
- Cautions
- Analogs
- Babies
- During pregnancy (and lactation)
- Reviews
- Price, where to buy
Composition
As part of the product contains the active substance orotic acid.
Product form
The tool is available as a powder, packaged in jars of dark glass.
Pharmacological action
Magnesium Orotate produces an antispasmodic, antiagregatine, antiarrhythmic effect, moreover, it makes up for the shortage in the body of magnesium and orotic acid.
The trace element magnesium is actively involved in the transport, conservation and utilization of energy, it is involved in the synthesis of proteins and nucleic acids, defines some mitochondrial processes. This trace mineral also provides control of the content of potassium inside cells.
Patients with myocardial infarction Magnesium reduces vascular resistance, activates the coronary blood flow, prevents the manifestation of coronary spasm. He is cardioprotectors, reduces the severity of heart failure.
Orotic acid is an endogenous metabolite which has been actively involved in the construction of pyrimidine bases that comprise nucleic acids. Under her influence, accelerate the processes of renewal, improving the synthesis of contractile proteins of the myocardium, it provides utilization of magnesium in the cells and expression of its influence.
Pharmacokinetics and pharmacodynamics
Data on the pharmacokinetics and pharmacodynamics not.
Indications
Magnesium Orotate prescribed to patients with the following diseases and conditions:
- cardiac arrhythmias, including - ventricular Arrhythmia in patients with digitalis intoxication;
- angina ;
- sharp myocardial infarction (for the prevention of arrhythmias);
- atherosclerosis ;
- arteritis;
- dyslipidemia;
- alcoholism , The state of withdrawal syndrome;
- Cachexia.
Also, funds designated for people in the diet which has low amounts of protein, as well as the observed low calorie daily diet. The medicine is used to compensate for a lack of magnesium is associated with increased body's need for this item. Such a condition can occur in pregnancy and breast-feeding women, as well as declining revenues, the assimilation of magnesium or increase its allocation from the body, associated with chronic diarrhea , Renal dysfunction, hypercalcemia, hyperthyroidism, hyperaldosteronism, and others.
Contraindications
Contraindications Magnesium Orotate such diseases are:
- impairment of renal function;
- urolithiasis disease At which marked the emergence of phosphate and magnesium-calcium stones;
- high sensitivity to the drug;
- liver disease acute and chronic nature;
- state sinoatrial and AV block.
Side effects
May include the following side effects in the treatment of drug Magnesium Orotate :
- unstable chair, in the treatment of high-dose - diarrhea;
- allergic manifestations dermatitis ;
- hepatodystrophy (for the treatment of patients with high-dose, low-protein-keeping diet ).
Instructions for use (method and dosage)
Magnesium Orotate must be taken orally with water (a small amount). Dosage is as follows: for 1 week must be taken by means of 1 g of 3 times per day. Further, should take on 0, 5g 2-3 times daily for six weeks. If necessary, treatment is continued for a longer period. If the patient concerned convulsions the muscles that occur at night, in the evening you need to take on the 1-1, 5 grams of the drug.
Overdose
In case of overdose may increase the intensity of side effects. This case is shown symptomatic therapy.
Cooperation
This feature reduces the level of absorption of iron, of sodium fluoride, tetracycline .
The drug reduces the likelihood of magnesium deficiency associated with deficiency of complications in the treatment of diuretics, cisplatin, aminoglycosides, amphotericin B, cyclosporine, methotrexate, pentamidine, laxatives.
Terms of sale
Prescription medications.
Storage conditions
Powder should be stored at temperatures not exceeding 25 ° C, keep away from children.
Shelf life
Shelf life PM - 4 years.
Cautions
If the patient prescribers iron, tetracycline and sodium fluoride must defer taking the drug for at least two hours.
If the patient has symptoms of unstable stools or diarrhea, the dose should be reduced.
The treatment can be carried out for a long time. Shortage of magnesium in the body can cause a number of diseases, unbalanced diet, alcoholism , The treatment of certain medicines, and others.
Analogs
Magnerot
Panangin
Asparkam
An analogue of the drug - a means Magnerot Which composition contains as active substance magnesium orotate dihydrate.
Babies
It is used to treat children under indications.
During pregnancy and lactation
During pregnancy and breast-feeding product is used only on prescription and with caution, as the gestation period increases the body's need for magnesium.
Reviews
Online there are many positive reviews about treatment with this drug. In particular, patients noted that Magnesium Orotate helps relieve leg cramps, improve overall health in many diseases.
Price magnesium orotate
Price magnesium orotate is an average of 160 rubles per pack of 20 tablets.
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