Description overdue on 01/12/2014
- Latin name: Tivortin Aspartatum
- ATC code: C01EB23
- Active substance: L-arginine aspartate
- Manufacturer: LLC "Jury-Farm", Ukraine
- Composition
- Product form
- Pharmacological action
- Pharmacokinetics and pharmacodynamics
- Indications
- Contraindications
- Side effects
- Instructions for use (method and dosage)
- Overdose
- Cooperation
- Terms of sale
- Storage conditions
- Shelf life
- Cautions
- Analogs
- Babies
- During pregnancy (and lactation)
- Reviews
- Price, where to buy
Composition
In Tivortin Aspartate formulation contains the active ingredient L-arginine aspartate and optional ingredients: saccharin sodium, sorbitol, propyl parahydroxybenzoate, methyl parahydroxybenzoate, water, flavoring.
Product form
It is produced in the form of a solution for oral application. Packed in bottles of 100 ml and 200 ml, which are packaged in cardboard boxes.
Pharmacological action
The drug acts as aspartate Tivortin membrane stabilizing . tsitoprotektornoe . antihypoxia . detoxification . antioxidant means . The active ingredient of the drug involved in the process for neutralizing the ammonia stimulate its excretion activates detoxifying liver function.
There hepatoprotective influence also means having a positive impact on the energy supply in the hepatocytes.
Tivortina aspartate reduce activation and adhesion of platelets and leukocytes to vascular endothelium is involved in the energy supply of the organism, as well as in the processes of spermatogenesis fibrinogenolysis.
There is moderate anabolic effect, stimulating activity of the thymus gland. The drug contributes to the process of synthesis, and insulin regulation of blood glucose levels during exercise, adjust the acid-base balance.
Pharmacokinetics and pharmacodynamics
Information on the pharmacokinetics of the drug is not provided.
Indications
Tivortin syrup used in the complex therapy of the following diseases:
- atherosclerosis cerebrovascular and heart;
- coronary artery disease ;
- arterial hypertension ;
- atherosclerosis peripheral vascular disease;
- Diabetic angiopathy ;
- heart failure in a chronic form;
- myocardiopathy ;
- status following acute blood flow disturbances in the brain after myocardial infarction ;
- hypercholesterolemia ;
- obstructive pulmonary disease with a chronic course;
- interstitial pneumonia ;
- pulmonary hypertension ;
- hepatitis of different origins of acute and chronic forms;
- liver disease;
- state hypoxia and asthenia ;
- for correction immunity with decreasing function of the thymus gland.
Contraindications
Do not use tool for severe kidney disease, high sensitivity to the components of the drug. No drug treatment practices in childhood.
Side effects
In rare cases, the feeling of discomfort in the small intestine, and stomach, feeling of nausea after ingestion of solution directly. These symptoms disappear on their own. In some cases, may occur allergic reactions .
Instructions for use (method and dosage)
Instructions on Tivortin aspartate It gives information on how the drug must be taken during the meals. The 1 measuring spoon - 1 g of funds. Instructions for use syrup provides that patients with coronary artery disease, atherosclerosis, diabetic angiopathy should take 5 ml of 3 to 8 times a day. Patients after acute myocardial infarction, and circulatory disorders in brain, people with hypertension, hypercholesterolemia, lung disease shows the drug in a dose of 5 ml 3-6 times a day.
In a similar dose Tivortin aspartate appointed people with hepatitis and other liver diseases. Patients with marked asthenia and hypoxic conditions, as well as patients requiring immunotherapy due to the deterioration of the function of the thymus gland, appointed on 5 ml 4-8 times a day. Duration of therapy - from 8 to 15 days.
Overdose
After taking large doses of the drug may be the reaction of high sensitivity and hypoglycemic condition. It should stop the treatment, wash the stomach and take products- sorbents .
Cooperation
If the drug is used at the same time Aminophylline , The patient may experience an increase in insulin levels in the blood. When taken at the same time Spironolactone and arginine increases blood levels of calcium. If previously the patient was taking potassium-sparing diuretics for the treatment of arginine he may increase the concentration of potassium in the blood. Tivortin aspartate can not be combined with T iopentalom .
Terms of sale
Buy Tivortin aspartate can be without a prescription.
Storage conditions
The solution must be stored in a place protected from moisture and light, with a temperature range from 15 to 25 C. It is necessary to protect the drug from children.
Shelf life
The shelf life of the preparation - 2 years.
Cautions
We must carefully apply the remedy for people who have observed kidney disease, and metabolic electrolytes. During treatment means you need to eat balanced, do not drink enough rest, stop smoking and use of psychostimulants.
It should immediately cancel treatment if his background is marked asthenia.
On the ability to manage traffic and work with dangerous machinery is not affected by the drug.
Analogs
- Metamax
- Deprenorm MB
- Dibikor
- Kardionat
- Mexicor
- Sulfokamfokain
- Qudesan
- Vero Trimetazidine
- Preductal
Analogs of the drug Tivortin aspartate - A drug Vazonat . Nukleinat-cardio . Nukleks . Neokardil .
Babies
There is no information about the safety of facilities for children up to the age of 18.
Tivortin during pregnancy and lactation
Tivortin syrup at pregnancy It applies only if indicated as active substance crosses the placenta. Treatment is carried out under the supervision of a physician. There is no evidence about the effects of drugs in the period breast-feeding .
Reviews Tivortine
Reviews Tivortine for oral use are rare. Patients say that the drug effectively eliminates the symptoms of diseases. The most pronounced effect is noted when it is used in the treatment.
Price Tivortin where to buy
Price Tivortin aspartate is about 400 rubles. per bottle.
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