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The analogue histamine . The main active ingredient is the current betahistine . Betaserk and histamine exerts vasodilating effects. Betahistine blocking histamine H3 receptor agonist is histamine H1 receptor benign. Effective action has on three levels: on the peripheral vestibular system, cochlear blood flow, central vestibular system . The mechanism of action of the drug is aimed at expansion of vessels in the inner ear. The effect is achieved due to the effect on the histamine H1, H3 receptors. In direct agonistic effects on H1 receptors in the blood vessels of the inner ear improves microcirculation , Increases the permeability of blood vessels, increasing blood flow in the basilar artery, normal endolymphatic pressure in the cochlea and labyrinth. Betaserk affects polysynaptic neurons of the vestibular nuclei in the structure of the brain stem by normalizing neuronal transmission . When exposed to the histamine H3 receptor raises the level of the neurotransmitter serotonin, which is able to reduce the activity of the vestibular nuclei. Betahistine reduces noise in the ears, reduce the intensity and frequency of vertigo, hearing loss when it contributes to normalization. Do not have a blocking effect on the histamine H1 receptors, so there is no sedation, it does not develop hypersomnia. Betaserk available in tablet form, in the form of drops for internal administration.
Indications:
Betaserk prescribed for labyrinth disorders , Lesions vestibular . dropsy of the labyrinth of the inner ear . labyrinthitis , Vestibular neurons Meniere's disease After neurosurgical operations. When atherosclerotic lesions of the blood vessels of the brain, post-traumatic encephalopathy genesis, vertebrobasilar insufficiency betahistine prescribed in the complex therapy.
Contraindications:
Betaserk not prescribed for betahistine intolerance, asthma, pheochromocytoma , Ulcerative lesions of the gastrointestinal tract in the acute stage, during pregnancy. Paediatric administered with caution.
Side effect:
Admission betahistine may be accompanied by facial flushing, bronchospasm , Drop in blood pressure, tachycardia , Dizziness, headache, angioedema , Skin rash, dyspeptic disorders.
Mode of application:
Betaserk Inside, after a meal. The drug at a dose of 24 mg taken twice a day, 1 tablet of 16 mg - three times a day ½ tablet 8 mg - three times a day 1-2 tablets. Patients notice improvement of health already in the early stages of therapy. Stable effect is reached after 2 weeks of treatment, increases in the next months of therapy. The drug is taken for a long time, the rate is determined individually.
Special instructions:
Betaserk not affect the speed psychomotor reactions , The management of complex machinery, driving a car. It does not cause drowsiness. Antihistamine drugs inhibit the activity of the drug Betaserk. Keep away from children, the recommended temperature - up to 25 degrees Celsius.
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