Description overdue on 08/08/2014
- Latin name: Rinostop
- ATC code: R01AA07
- Active substance: Xylometazoline (Xylometazoline)
- Manufacturer: Of OJSC "Pharmstandard», Russia
- Composition
- Product form
- Pharmacological action
- Pharmacodynamics and pharmacokinetics
- Indications Rinostopa
- Contraindications
- During pregnancy (and lactation)
- Side effects
- Instructions on Rinostop
- Overdose
- Cooperation
- Terms of sale
- Storage conditions
- Shelf life
- Analogs
- Reviews
- Price, where to buy
Composition
Spray Valium :
- active substance Xylometazoline hydrochloride - 0, 1, or 50 mg, 00 mg;
- Excipients: edetate disodium . sodium chloride . benzalkonium chloride . potassium dihydrogenphosphate . sodium hydrogen phosphate dodecahydrate Purified water to 1 ml.
Nasal drops :
- active substance xylometazoline hydrochloride - 0, 1, or 50 mg, 00 mg of
- Excipients: benzalkonium chloride, edetate tirinatriya . monobasic potassium phosphate . dibasic sodium phosphate Sodium chloride, purified water to 1 ml.
Product form
- spray nasal 0, 1% for adults and 0 to 05% of children from 2 to 6 years at 10, 15, 20 or 30 mL in plastic bottles placed in the carton;
- nasal drops Rinostop 0.1% for adults of 0.05% for children from 2 to 6 years 10, 15 and 20 ml vials with dropper-cap, placed in a cardboard box.
Pharmacological action
The medicine has a local vasoconstrictive action, relieves edema, reduces the symptoms of runny nose and zalozhennost a nose.
Pharmacodynamics and pharmacokinetics
Active substance Rinostopa ksilometazolin It refers to the group alpha-agonists the local vasoconstrictor effect. Alpha-adrenoceptor agonists - are drugs that stimulate alpha-adrenergic receptors , Located in the walls of blood vessels and responsive to epinephrine, norepinephrine and other substances having a similar effect.
When applied to the nasal mucosa causes narrowing of drug disposed therein blood vessels, but is almost absorbed into the blood and does not have a general (systemic) action on the human organism. This reduces blood flow in veins and significant reduction propotevanie liquid portion of blood through the vascular walls. As a result of rapidly removed mucosal edema, nasal breathing is restored. Also decreases the amount of bleeding from the nose. Eliminating swelling in the nasal cavity uluchaet also state the hearing aid.
Thus the preparation has no adverse effect on the mucous membrane, including at its mucociliary cleansing the nasal cavity from contamination. Prolonged use of drops or spray (more than 5 - 7 days in a row) can lead to paresis of smooth muscles of of blood vessels and of their prolonged the expansion of, An attendant Persistent edema and zalozhennostju a nose.
The action of the drug starts after a few minutes immediately after it has been applied to the nasal mucosa and can take several hours.
Indications Rinostopa
The drug is used:
- when nasal congestion and runny nose on the background acute respiratory disease ;
- in chronic, including allergic rhinitis, nasal congestion accompanied by short courses;
- acute and chronic sinusitis ( sinusitis . sinusitis ), Accompanied by nasal congestion short courses;
- acute and chronic otitis to relieve swelling auditory tube that connects the middle ear to the nasopharynx;
- for diagnostic studies (e.g. rinoskopii ) ENT-organs.
Contraindications for use Rinostopa
The drug is contraindicated in:
- glaucoma ;
- chronic atrophic (with a decrease in the volume of the mucous membrane) rhinitis;
- high blood pressure;
- tachycardia ;
- hypersensitivity to the drug;
- while the appointment of certain drugs for the treatment of depression ( MAO inhibitors and tricyclic antidepressants );
- after surgery in the meninges;
- children up to 2 years.
Precautions vasoconstrictor drops and spray should be applied:
- diabetes ;
- hyperthyroidism ;
- Heavyweight atherosclerosis Complicate coronary heart disease ;
- prostatic hyperplasia ;
- breast-feeding.
Rinostop during pregnancy
When pregnancy Rinostop contraindicated due to the fact that it causes a spasm of small blood vessels. This creates an increased risk of preeclampsia .
Side effects Rinostopa
Side effects are manifested in the mainly at an overdosage, prolonged (more than 5 days in a row) the application of or at presence of the of contraindications for the application of of this drug. In such cases, often appear dryness in a nose . burning . sneezing Sometimes enhanced by a runny nose.
Less long-term use side effects are manifested in the form of a sharp expansion of the blood vessels of the nasal mucosa, which is accompanied by mucosal edema, nasal congestion and copious and violations of nasal breathing.
Furthermore, during prolonged uninterrupted application spray droplets and mood changes can occur in the form of depression.
Instructions on Rinostop
0, 1% spray used in adults and children after 6 years. Spray sprayed after removal from the vial cap. The atomizer is introduced into one nostril and then press on the base and is applied for a second medication. Then the dispenser into the second nostril and repeat manipulation. Repeat the procedure can be not more than 3 - 4 times per day. Instructions for use as a spray Rinostopa children 2 - 6 years, provides for the introduction of 0, 05% do not spray more than three times a day.
0, 1% of the droplets in the nose is also used in adults and children 6 years of age after 1 - 2 drops in each nostril no more than three times a day. 0, 05% children Rinostop administered to 1 - 2 drops in each nostril no more than twice a day.
Rinostop - Is it possible to overdose?
Overdosing is possible, it manifests itself in the form of increased side effects. Treatment - removal of the drug.
Rinostopa Interaction with other drugs
Rinostop can not be taken simultaneously with certain medications intended to treat depression - MAO inhibitors and tricyclic antidepressants.
Terms of sale
The drug belongs to the drugs without prescription.
Storage conditions
Rinostop should be stored out of reach of children at a temperature of not less than 2 and not more than 25 ° C.
Shelf life
Lekarstva- Shelf life 2 years from date of manufacture.
Analogs Rinostopa
Tizin Xylo
Rinonorm
Xylene
Naphazoline
Otrivin
Sanorin
Nazivin
Galazolin
Noksprey
Naphthyzinum
Analogs - a variety of dosage formulations groups which are used to treat the same disease. Analogs Rinostopa - drugs relieve swelling of the nasal mucosa: naphazoline ( Naphthyzinum . Sanorin ), Oxymetazoline ( Nazivin . Nazol . Knox Spray ), Phenylephrine ( Nazol-baby ), Tetryzoline ( Tetrino ) Tramazolin ( Mucosolvan Reno ) Dimethindene + phenylephrine.
Reviews Rinostope
Reviews Rinostope mostly positive. The drug quickly relieves swelling in the nasal cavity and significantly reduces nasal discharge. Side effects occur only during prolonged use at high dosages.
Negative comments about Rinostope are rare and are associated with long-term use and overdose.
Price Rinostopa
Price Rinostopa in Moscow:
- Rinostop nasal drops 0, 1% and 0 05 ml of 10% - 21 - 25 rubles;
- nasal spray 0, 1% and 0%, 15 ml 05 - 56 - 65 rubles.
Tablets Rinostop, manufacturing pharmaceutical company Bosnalek (Bosnia and Herzegovina) are not synonymous with drops and sprays Rinostop because they have a different composition.
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