Description overdue on 05/22/2014
- Latin name: Sorbifer Durules
- ATC code: B03AA07
- Active substance: Ascorbic acid + iron sulphate
- Manufacturer: OAO Pharmaceutical plant Egis, Vergriya
- Composition
- Product form
- Pharmacological action
- Pharmacodynamics and pharmacokinetics
- Indications
- Contraindications
- Side effects
- Instructions for use Sorbifer Durules (method and dosage)
- Overdose
- Cooperation
- Terms of sale
- Storage conditions
- Shelf life
- Analogs
- With alcohol
- During pregnancy (and lactation)
- Reviews
- Price, where to buy
Composition
One tablet Sorbifer Durules contains active ingredients: iron sulfate - 0, 32 g, ascorbic acid - 0, 06 r + auxiliaries ( povidone, carbomer 934P, makrolog 6000 strearat magnesium polyethene powder, titanium dioxide, wax, hypromellose, iron oxide yellow ).
Product form
The drug is released in the form of tablets Yellow, convex, with the letter Z with one hand. If you break the tablet in half, we will see the core of gray. In packs of 30 or 50 pieces.
Pharmacological action
The drug has iron antianemic effects on the body.
INN medications: ferrous sulfate + ascorbate .
Pharmacodynamics and pharmacokinetics
The therapeutic properties of the drug due to the presence in its composition of iron in combination with ascorbic acid .
Iron In itself, it is an integral part of the human body, its important functional unit. It is part of the hemoglobin participates in oxidative reactions in tissues. Ascorbic acid enhances the quality and affects the rate of iron absorption by the body.
A special form, matrix In which the drug is released, it provides a gradual and slow release of iron. The process takes place not in the stomach, and duodenum and jejunum , Under the influence peristalsis . The process is characterized by a high degree of Absorption and Bioavailability . More than 90% of the active iron bound to blood proteins. The half-life of about six hours.
Indications
The medicine is prescribed:
- at iron deficiency in the body;
- anemia (due to lack of iron);
- as a preventive measure in pregnant and lactating women, and blood donors.
Contraindications
- drug allergy ;
- hemosiderosis and hemochromatosis ;
- other anemias ;
- thrombosis and thrombophlebitis ;
- diabetes and fructosemia ;
- stenoses digestive tract;
- urolithiasis disease and other severe kidney disease;
- children (under 12 years);
- concurrent administration of drugs containing iron, a problem with absorption of iron in the body.
When inflammation and peptic ulcer digestive tract means used for its intended purpose and only under medical supervision.
Side effects
The most common side effects are:
- constipation, diarrhea, nausea and pain epigastric area;
- redness and itching of the skin, it is possible angioedema ;
- hyperglycemia ;
- the drug promotes the formation of sand and stones in the kidneys;
- thrombocytosis, erythropenia, leukocytosis ;
- deviations from normal maintenance and exchange of zinc and copper in the body;
- headache, weakness, palpitations, dizziness;
- blackening or darkening of the feces.
Instructions for use Sorbifer Durules (method and dosage)
According to the instructions on Sorbifer, swallow the tablet whole without chewing, and not divided into parts, washed down with water.
As a rule, if the doctor has not appointed another, the daily dose is 2 tablets (maximum of four), divided into two doses. The course of treatment can be 3-4 months.
How to take the medication during pregnancy?
The prophylactic, administered one tablet per day during the treatment - 2 tablets. Therapy continues to restore the level of iron in the body.
Overdose
Fatigue, weakness . lowering blood pressure . stomach ache and vomiting blood are signs of an overdose.
It should be as soon as possible to seek help from your doctor, make gastric lavage, drink human milk and raw egg, to introduce deferoxamine .
Cooperation
It is not necessary to combine the drug with ciprofloxacin, norfloxacin, levofloxacin, ofloxacin and moxifloxacin .
We do not recommend the combination of dietary supplements containing calcium and magnesium, captopril, clodronate, cimetidine, levodopa, zinc desferoksamina, methyldopa, tetracycline penitsilinamina, thyroid hormones, pancreatin ethanol and tocopherol with Sorbifer. The interval between drug administration should leave at least two hours.
The combination of the drug with ascorbic acid may lead to overdose with iron.
The process of absorption of the drug degrades in combination with milk . eggs . tea . coffee . juices . bread , Foods rich in dietary fibers. Also, the absorption of negative impact oral contraceptives and chloramphenicol .
Terms of sale
It requires a prescription.
Storage conditions
In the reach of children, the temperature is not above 25 degrees.
Shelf life
3 years.
Analogs Sorbifer Durules
Tardiferon
Feroplekt, gemoferon, Fearon fort globigen, aktiferin, gemsinerad-td, totem ranferol-12 .
Price analogs slightly lower than the original.
Is it better or Maltofer Sorbifer?
Preparations are almost identical, it is believed that Maltofer better absorbed and has fewer side effects. All individually.
Is it better or Sorbifer Fenyuls?
Fenyuls It contains twice less iron than Sorbifer. It helps with low degrees of anemia. Original quickly cope with the symptoms of the disease.
With alcohol
In combination drug with ethanol, enhanced degree of absorption of iron. Perhaps increased adverse reactions.
Sorbifer during pregnancy and lactation
Sorbifer prescribed for pregnancy anemia .
According to the instructions, the initial terms pregnancy (first six months) recommended intake of one tablet of the drug once a day. Last trimester and breastfeeding - 1 tablet twice a day.
Treatment is continued until until normal levels of iron in the blood. Prescribed by a doctor, receiving the drug may be extended up to 6 months.
Reviews Sorbifer Durules
Reviews pregnancy are good. Restoring the hemoglobin level is fast. Side effects at the recommended dosage, appear infrequently. Some women prefer to wash down pills with alcohol, which increases the effectiveness of the drug, despite the fact that alcohol intake during pregnancy is extremely undesirable.
Price Sorbifer Durules (Where to buy)
What is the cost to buy the drug in Ukraine? The average price 30 tablets It is about 70 USD. Price 50 tablets - About 80 USD.
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