Description overdue on 04.06.2014
- Latin name: Coldact Flu Plus
- ATC code: N02BE51
- Active substance: Paracetamol + Phenylephrine + Chlorphenamine (Paracetamol + Phenylephrine + Chlorphenamine)
- Manufacturer: Natco Pharma (India)
- Composition
- Product form
- Pharmacological action
- Pharmacodynamics and pharmacokinetics
- Indications
- Contraindications
- Side effects
- Instructions on Koldakt (method and dosage)
- Overdose
- Cooperation
- Terms of sale
- Storage conditions
- Shelf life
- Analogs
- During pregnancy (and lactation)
- Reviews
- Price, where to buy
Composition Koldakta
The preparation Koldakt includes active ingredients phenylpropanolamine hydrochloride - 0 5 + d chlorpheniramine maleate - 0, and 08 g of additional material comprising a gelatin shell.
As a part of Koldakt Flew Plus Capsules active substances: paracetamol - 0, 2 g; maleate chlorphenamine and - 8 mg; phenylephrine hydrochloride - 25 mg, and adjuvants ( Hypromellose, MCC, talc, ethyl cellulose, povidone, diethyl phthalate, isopropanol, dyes, sucrose, water, sodium bisulfite, starch syrup, edetate disodium, sugar crumbles ).
The suspension Flew Plus It contains the active ingredients: maleate chlorphenamine - 2 mg; paracetamol - 0, 125 g; phenylephrine hydrochloride - 5 mg plus carmellose sodium, propyl parahydroxybenzoate, edetate disodium, methyl parahydroxybenzoate, saccharinate sodium, sodium chloride, MCC, glycerol, sucrose, ksantovaya gum, dioksid silicon, aromatizatory, polysorbate 20, citrate sodium, Water, citric acid .
Product form
Koldakt release capsules long-acting a shell of gelatin, packages of 10 pieces.
Koldakt Flew Plus - In two forms:
- capsule shell gelatin, half red, half clear, inside - yellow, red and white pellets, in packs of 10-100 pieces;
- a suspension for internal application ,, Viscous, orange, with a specific smell, in bottles of 60 ml.
Pharmacological action
Antihistamine effect , Constricts blood vessels. Antikongestivnoe .
Flew Plus also has antipyretic and analgesic action.
Pharmacodynamics and pharmacokinetics
Part of the tablets Koldakt and Koldakt Plus chlorpheniramine It is the most effective antihistamine That reduces the impact on the H1 receptors . It also has a minor sedative and antimuscarinic effect. The substance has the ability to reduce the permeability of the cells lining the nose, thus reducing the unpleasant symptoms (itching and swelling).
The process of interaction with blood plasma is slow. Maximum concentration - through 2-6 hours, is metabolized in the body. However, a small part of its output via the kidneys.
Other active ingredient - phenylpropanolamine It is simptatomimetikom . Affects alpha-adrenergic receptors , But less than, for example, ephedrine . It has vasoconstrictor, anti- the mucous membrane of the nose and paranasal sinuses.
It reaches a maximum concentration for the past 2 hours. Output is through the kidneys.
Paracetamol It reduces body temperature and pain. Helps eliminate cold symptoms - headache, joint and muscle pain, discomfort in the throat.
Blood proteins binds poorly, at least 10% is metabolized in the liver, concentration of max - 3 hours. Conclusion excretion occurs within days after administration.
Indications
- rhinitis ( vasomotor or Allergic );
- elimination of symptoms of colds as allergy, swelling, runny nose, stuffy nose .
Contraindications
Taking the drug in capsules are not recommended for children under 12 years, of drug allergy any of the components.
The suspension can be administered to children from 6 years.
Flew Plus It has a number of additional contraindications:
- coronary atherosclerosis ;
- thyrotoxicosis ;
- severe kidney disease, liver, heart, gall bladder;
- diabetes and glaucoma ;
- gastric ulcer .
Side effects
I do not occur often:
- drowsiness, headache, excitement and excessive irritability;
- heparin and nephrotoxic effects;
- dryness of mouth, diarrhea, nausea, loss of appetite ;
- increase Blood Pressure Problems with vision;
- chest pain, dysuria ;
- pain epigastric , Appetite loss.
Instructions on Koldakt (method and dosage)
The duration of administration and dosage must appoint a physician.
According to the instructions for use Koldakta, adults appoint 2 capsules a day, distributed into 2 admission.
The course of treatment 1-3 ( influenza, SARS ) Up to 30 days.
Instructions for use Koldakt Flew Plus
According to the instructions on Koldakt Flew Plus appoint two capsules a day, at regular intervals.
Syrup Shake well before use.
Adults appoint 30 - 40 ml per day, for 3-4 hours. Children from six years - 15-20 ml for 3-4 hours.
The treatment usually is not more than five days.
Overdose
The cases are not registered. Therapy - according to symptoms.
For a form, which includes acetaminophen Symptoms include: nausea, gepatonekroz , Paleness and weakness, loss of appetite. As soon as possible to see a doctor, and wash out the stomach, enter donators of SH-groups . methionine (first 8 hours), or N-acetylcysteine (12 hours).
Cooperation
With caution used in conjunction with MAO inhibitors, tricyclic antidepressants, halothane guanethidine, furazolidone .
The drug is not compatible with ethanol .
Do not take a paracetamol - barbiturates, carbamazepine, zidovudine, phenytoin and rifampicin . Effectiveness urikozuricheskih means decreases.
Terms of sale
Prescription.
Storage conditions
The dry, cool place.
Shelf life
Koldakt - 3 years.
Koldakt Flew Plus - 2 years.
Analogs
Neo Sedalgin
Rinzasip
Kaffetin Light
Kaffetin
Rinikold
Rinzai
Tsefekon
Antigrippin
Tylenol
Coldrex
Theraflu
Flyukold
Farmatsitron
Solpadein
Paracetamol
Fervex
Efferalgan
Panadol
The most common analogs are: anzhisept, Rinzai, angileks, Aqua Maris, anginal, anti-angina vokasept, geksaliz, Hexoral, gripkold, dekatilen, kameflyu effect Flu, antiflu, koldfri, koldreks, Theraflu, farmatsitron, Fervex .
During pregnancy and lactation
Koldakt at pregnancy and lactation is not assigned.
Reviews Koldakte
Reviews of Koldakte not so much. But of those that are dominated by the positive. Colds and flu with a preparation to carry lighter, faster passes runny nose and other unpleasant symptoms. Because of the side effects most frequently manifested drowsiness.
Reviews Koldakte Flew Plus good. The drug is quickly lowers the temperature, relieves nasal congestion, is relatively inexpensive. In a review of Koldakte Flew Plus drawback considered side effects, mostly sleepy.
Price Koldakta (Where to buy)
Approximate price Koldakta about 98 rubles per 10 pieces.
Cost Koldakt Flew Plus 10 capsules - 115 rubles.
Cost Koldakt Flew Plus Syrup - 100 rubles.
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