Description overdue on 10/12/2014
- Latin name: Olfen
- ATC code: M02AA15
- Active substance: Diclofenac (Diclofenac)
- Manufacturer: Mepha, Lda. (Switzerland)
- Composition
- Product form
- Pharmacological action
- Pharmacodynamics and pharmacokinetics
- Indications
- Contraindications
- Side effects
- Instructions for use Olfen (method and dosage)
- Overdose
- Cooperation
- Terms of sale
- Storage conditions
- Shelf life
- Reviews
- Price, where to buy
Composition
Olfen (Olfen) is composed of an active component such as diclofenac .
Additional components: lactic acid, isopropyl alcohol, hydroxyethyl cellulose, purified water, di-izopropiladipat, sodium metabisulfite, hydroxypropyl cellulose.
Product form
The tool is available as a gel patch and Candles . Rarer forms - dragee, capsule, solution, tablet.
Pharmacological action
The drug belongs to nonsteroidal antiinflammatory funds intended for topical application.
Pharmacodynamics and pharmacokinetics
Gel Olfen is designed for outdoor use. The active substance passes through the skin and accumulate in the tissues at the site of application. In the presence of inflammation acts as painkiller means, reduces the severity of edema, speeds up recovery, removes inflammation, cools the skin.
After applying the active ingredient found in blood plasma, synovial membrane and synovial fluid.
The degree of association of the drug to plasma proteins - almost 100%. Plasma half-life - 60-120 minutes.
Patch Olfen - means long (up to 12 hours), its innovative shape provides uniform release of the active substance ( diclofenac ) In a selected area of skin. It is also, as the gel enters the tissue through the skin and reduce pain, swelling and inflammation. The tool also has a cooling effect, and that is of great importance for bruises, joint pain and back pain, sprains.
Other forms of release of the drug also have anti-inflammatory . pyretic and analgesic action. They are effective for pain of inflammatory nature.
Indications
This medicament is used when necessary symptomatic treatment of pain, swelling and inflammation of:
- soft tissue injuries: injuries of muscles, tendons, joints, ligaments;
- bursitis ;
- local forms degenerative rheumatism ;
- Tendon ;
- localized forms rheumatism soft tissue;
- shoulder syndrome ;
- periartropatii .
Contraindications
The medicine should not be taken if:
- hypersensitivity to its components;
- in the presence of history asthma attacks, acute rhinitis or hives Which are caused by taking NSAIDs ;
- exacerbation duodenal ulcer disease and stomach ;
- burns;
- eczema ;
- Open skin lesions;
- infections of the skin.
Side effects
Side effects noticeable mainly in the form of a slight temporary skin reactions local character. Rarely observed allergy . pustular rashes, bronchial asthma , Hypersensitivity reactions and sensitivity, angioedema . itch , Burning of the skin. Furthermore, there may be:
- rash;
- erythema ;
- eczema ;
- dermatitis .
Instructions for use Olfen (method and dosage)
The gel is applied depending on the surface area of the site to be processed. Generally applied 2-4 g of gel (about 1-2 cm) in the 400-800 square meters. cm skin. The tool is used 3-4 times during the day. Apply to the affected area, but not rubbed. The daily dosage not greater than '15 Guide Olfen on a gel informs that it can be used in conjunction with other forms of the drug.
The course of the application depends on the individual readings and causes of therapy. Experts recommend checking the feasibility of its continuation after two weeks.
But you can not use the gel longer than 14 consecutive days in the soft tissue or available rheumatic soft tissue diseases. When pain, caused by arthritis Exchange rate no longer than 21 days, if the specialist is not appointed otherwise.
If after a week the state was no better, it is advisable to stop using the gel and consult your doctor.
If you are using the patch Olfen, instruction on the application reports that it is necessary to stick to the affected area 1-2 times a day. The skin where the means used must be clean and dry. You can not pre-lubricate it with cream. Cast plaster need without stretching it. When used in mobile joints, for example, on the elbows, it is desirable to strengthen the bandage by means of the mesh.
Before hygiene plaster can be removed and then re-stick.
For children of 6-12 years is better to use the medicine in the form of tablets of 25 mg of normal duration. Daily dose - 2 mg / kg. In the presence of Juvenile Rheumatoid Arthritis it can be increased by 1 mg / kg. The tablets are taken as a whole, before eating, not chewing, drink water.
Pills prolonged Actions taken by 100 mg once a day. In the presence of dysmenorrhea and attacks migraine assigned to 200 mg per day.
In a form suitable for internal administration, the maximum daily dosage of the drug - 150 mg. Before introduction means should be diluted in 100-500 ml of 0 9% saline solution or 5% dextrose solution, before adding a solution of sodium bicarbonate 1 4 ml, 2% solution of either 0, 5 ml of 8, 4%. Depending on pain infusion is performed for 30-180 minutes. To prevent post-operative pain medication is administered for 15-60 minutes at a dose of 25-50 mg. In further infusion is performed at 5 mg / h, until reaching the maximum daily dosage (150 mg).
It is also possible intramuscular administration of the drug (150 mg once) for the treatment of acute conditions, or preventing exacerbation of chronic diseases. Then continue taking the treatment Olfena in forms intended for oral application. The maximum daily dose is still 150 mg.
Candles Olfen used rectally at a dosage of 100 mg for early signs of attack migraine . If necessary, the same dose is administered repeatedly.
Overdose
No cases of overdose have been reported by the tool. In applying the drug in high doses may cause systemic adverse reactions. In this case it is necessary to take appropriate measures in case of intoxication NSAIDs for oral use.
Cooperation
Olfen increases plasma levels M etotreksata . lithium preparations . Digoxin and Cyclosporine . In addition, it reduces the efficiency of diuretics , on the background anticoagulants . thrombolytic and antiplatelet drugs increases the risk of bleeding. When interacting with kalisberegatmi diuretics It increases the likelihood of hyperkalemia . Reduces action antihypertensive . hypoglycemic and hypnotics drugs. It increases the possibility of adverse reactions to other NSAIDs and GCS (in particularly common cases - bleeding from the gastrointestinal tract). Furthermore, it increases toxicity Methotrexate and nephrotoxicity Cyclosporine .
The combination of the drug with Paracetamol It makes it more likely the development of nephrotoxic effects of the active substance Olfena. When interacting with ethanol . Corticotropin . Colchicine and means that contain St. John's Wort increases the risk of bleeding in the gastrointestinal tract. Drugs which lead to photosensitivity , Increase sensitizing Action of active substances Olfena UV. Medication-blockers tubular secretion increase the content diclofenac plasma, so its dosage necessary corrections.
Terms of sale
The tool is available without prescription.
Storage conditions
The optimum temperature for storage of the drug to 25 ° C.
Shelf life
The patch can be used for 4 months after opening the package and 6 months when stored in the refrigerator.
Gel candles are kept up to 3 years.
Reviews
Reviews Olfen plaster and other dosage forms of the funds mostly positive. People celebrate its ease of use and effectiveness.
Price Olfena where to buy
Price Olfena depends on the release form. The gel can often be found in the Ukrainian pharmacies. The tubes of 50 grams it costs about 70 hryvnia, and in tubes of 20 grams - about 50 hryvnia.
In addition, the popular form of the drug is plaster. It is also sold mainly in Ukraine. Price patch Olfen - about 85 hryvnia. Buy patch in Kiev and other cities in Ukraine can be almost any drugstore.
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