Tavegil

Description overdue on 24.12.2011

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The anti-allergy. It is derived ethanolamine , Histamine blockers H1 receptors. Basically, the active compound in the drug acts Tavegil clemastine . In addition to the anti-allergic effects, providing m-anticholinergic, sedative effect, reduces vascular permeability. The drug does not have a soporific effect. Tavegil prevents smooth muscle contraction, development vasodilation Due to the action of histamine. Clemastine reduces itching, has local anesthetic effects, inhibits the formation of edema, exudation It reduces the permeability of the capillary wall. During the experiment, it was found that Tavegil has no teratogenic, mutagenic, carcinogenic effects . When you receive a dose 300 times higher than normal, reduced fertility . After ingestion of the maximum effect is recorded after 6 hours, it lasts 12 hours. Tavegilum available in tablet form, in the form of a syrup, a solution for injection.

Indications:

Tavegil prescribed for allergic urticaria , Hay fever, allergic rhinitis, eczema, itching dermatoses , Contact dermatitis, medication allergy Allergies to insect stings. The drug is effective in hemorrhagic vasculitis . serum sickness , Pseudoallergic reaction, anaphylactic shock, acute iridocyclitis .

Contraindications:

Tavegil contraindicated in pregnancy, intolerance to clemastine, breastfeeding. The drug is not used in the treatment MAO inhibitors, bronchial asthma, diseases of the lower respiratory tract, in pediatrics. At stenosis of the pylorus , Bladder outlet obstruction, angle-closure glaucoma, prostatic hyperplasia, diseases of the heart, thyrotoxicosis , Hypertension Tavegil used with caution. Babies under one year is prescribed drug in the form of solutions for injection, syrup. A tablet form of the drug can be taken on reaching the age of 6.

Side effects and overdose:

Nervous system : Tremor of the extremities, dizziness, increased drowsiness, fatigue, fatigue, headaches, loss of coordination of movements, lethargy. Children marked stimulating effect of the drug on the nervous system, manifested convulsions, euphoria , Agitation, anxiety, neuritis . paresthesias , Hysteria, insomnia. Senses : noise in ears, Acute labyrinthitis , Diplopia, disturbances of the visual analyzer. Digestive system : stomachalgia , Diarrheal disorders, stool, vomiting, loss of appetite, dry mouth. The urinary system : Difficulty in urinating, frequent urge. Respiratory system : Nasal congestion, disorders and difficulty in breathing, pressure in the chest, difficulty in sputum, thickening of the bronchial tree secretions. Cardiovascular system : arrythmia , Tachycardia, drop in blood pressure. Forming Organs : Agranulocytosis, thrombocytopenia, hemolytic anemia . Perhaps the development of bronchospasm , Anaphylaxis, dyspnoea, photosensitization . If overdose is marked stimulation of the nervous system, anticholinergic effects: disturbances in the digestive tract, blood flow to the skin of the face, fixed dilated pupils, dry mouth. It is recommended gastric lavage 0, 9% NaCl, reception laxatives, posimptomnaya therapy.

Mode of application:

A tablet form of the drug is taken orally twice daily at a dose of 1 mg. The maximum permissible daily amount of the drug Tavegil - 6 mg. Babies: for 0, 5 mg twice a day. Children under 6 years Tavegil appoint syrup 1 teaspoon. Intravenous and intramuscular administration of the preparation is carried out twice a day to 2 mg, are administered to children at 12, 5 mg / kg two times. In order to prevent allergies is administered by slow intravenous injection of 2 mg clemastine once. The contents of the ampoule should be dissolved in 0 9% NaCl.

Special instructions:

The solution for injection contains ethanol . During treatment, it is recommended that the admission of alcohol. Not allowed intra-arterial injection of the drug. For elderly patients, children require close monitoring during treatment. Tavegil cancel 72 hours prior to the allergy test to exclude results prick allergy tests . Tavegil effect on driving vehicles, the management of complex mechanisms.

Drug Interactions:

Tavegil enhances the effect of neuroleptics (antipsychotic), hypnotics, sedatives, Mr. holinoblokatorov . Not allowed simultaneous application MAO inhibitors .