Sydnopharm

Description overdue on 08/08/2014

• Latin name: Sydnopharm
• ATC code: C01DX12
• Active substance: Molsidomine (Molsidomine)
• Manufacturer: Sopharma AD, Bulgaria

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• Composition
• Product form
• Pharmacological action
• Pharmacodynamics and pharmacokinetics
• Indications Sydnopharm
• Contraindications
• Side effects
• Sydnopharm, instructions for use (method and dosage)
• Overdose
• Cooperation
• Terms of sale
• Storage conditions
• Shelf life
• Analogs
• Reviews
• Price, where to buy

Composition

One tablet contains 2 mg molsidomine   + Additional substances ( wheat starch, colloidal silicon dioxide, lactose, mannitol, magnesium stearate, peppermint oil, microcrystalline cellulose, hydroxypropylmethylcellulose, E110 ).

Product form

The drug release in the form of convex round tablets pink, scored on one side. The tablets have a specific smell of mint. Packages of 30 pieces.

Pharmacological action

Peripheral vasodilators .

Pharmacodynamics and pharmacokinetics

The active substance stimulates the process of increasing the concentration cGMP Which, in turn, weakens vascular smooth muscle cells . Thus, the preload decreases and the body's need for oxygen. Vasodilatation occurs in cardiac muscle. It improves blood circulation, increases the endurance of the heart, reduces the number of attacks angina .

Blood clotting is reduced, thanks to the ability molsidomine   inhibit the early phase platelet aggregation . If there is a chronic heart failure, the drug has the ability to reduce the size of the heart chambers, tension myocardium A quantity of blood in the left ventricle.

After oral administration, the drug is absorbed through the half-hour at sublingual   - in 10 minutes. The maximum effect means reaches half an hour - an hour, this condition lasts for 6 hours. Undergoes metabolism in the liver, the kidneys displayed.

Indications Sydnopharm

The drug is prescribed for the prevention and treatment of (relief) attacks Angina:

• in chronic Heart Failure   (in combination with other drugs);
• in acute left ventricular failure;
• hypertrophy of the right ventricle on the basis of diseases that disrupt the normal functioning of the lungs;
• at elevated pressure l egochnom circulation .

It is also an indication for use is Sydnopharm myocardial infarction   (but only when stabilized hemodynamic   indicators).

Contraindications

The drug should not be taken:

• in the acute period (!), myocardial infarction   (especially compared to the reduced pressure);
• glaucoma ;
• drug allergy   into components;
• reduced pressure (above 100 mmHg);
• cardiogenic shock ;
• in old age;
• in vascular collapse   ;
• at toxic pulmonary edema ;
• in disorders of blood circulation in the brain.

The drug is not prescribed to pregnant and lactating women, in conjunction with Sildenafilom Children under 18 years.

It should be particularly careful when tendency to low blood pressure, after suffering hemorrhagic stroke .

Side effects

The high probability of decline Blood Pressure , Occurrence tachycardia , Redness of the face, appearance vascular collapse , Nausea,   anorexia , General weakness. Might appear allergic reactions .

Sometimes early treatment can occur headache, dizziness, nausea and vomiting, but after a while, these effects are.

Sydnopharm, instructions for use (method and dosage)

The tablets are taken orally or sublingually   (if necessary) during a meal or after a meal.

Mode of administration and dosage must appoint a physician, depending on the frequency of attacks and the nature of the disease. Duration of reception must also be determined by a physician.

According to the instructions for use Sydnopharm, the maximum daily dose is 12 mg funds. As prophylaxis designate the first few days, half or a whole tablet of four to six times per day. Further, the daily dose can be increased up to 8 mg, distributing it into 2-3 doses.

In the acute phase of the disease, generally, the dosage is increased up to 4 tablets for 3-4 hours.

Overdose

Symptoms of overdose include: severe headache, bradycardia . hypotension , Nausea, and possible collapse.

As treatment produce gastric lavage, enterosorbents . diuresis , Eliminating the symptoms of overdose.

Data on the effectiveness of Dialysis   an overdose is small.

Cooperation

The drug is strictly forbidden to combine with alcohol.

Vasodilators,   antihypertensives Increase the likelihood of collapse   and critical reduction BP .
a tsetilsalitsilovaya acid   when combined with Sydnopharm has a stronger antiagregatnoe action .

Do not combine the drug with Sildenafilom .

Terms of sale

To purchase the drug requires a prescription.

Storage conditions

Store in a cool, dry place (not above 25 degrees), away from children.

Shelf life

3 years.

Analogs Sydnopharm

Analogues of drugs are Dilasidom, Molsidomine, Korvamin   and Korvaton .

Reviews Sydnopharm

The drug has mixed reviews. Many drugs helps improve overall health, reduce the incidence of atrial fibrillation   on the background of physical activity. For some, the effect of the agent is not sufficient and they move on to receive other funds. In any case, the question of the discontinuation or changing the medication should be decided with the doctor, all highly individual.

Often at the beginning of the reception means of headaches and nausea, but a week later, this effect takes place.

Price Sydnopharm where to buy

Price Sydnopharm is about 137 rubles for 30 tablets of 2 mg.

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