Thursday, September 21, 2017

Scientists have found in the human brain "molecule unhappiness"

Scientists have discovered a so-called "misery molecule" in the brain, which affects the process of stress, anxiety and depression. Now we have to create a drug that blocks the action of this molecule.

 Scientists have found in the human brain "molecule unhappiness"  medicine for depression

It's about a protein called CRF1, which is released by the pituitary gland. How do I find researchers from the British company Heptares Therapeutics, a protein that promotes the release of hormones associated with stress, anxiety and depression. Its scientists have made a discovery by one of the world's most powerful X-ray machines - Diamond Light Source.

Science has long been known that the pituitary gland controls the body's stress response, releasing specific hormones. But now researchers have found out who exactly is responsible for this process. CRF1 protein contained in the inner membrane of pituitary cells. Further work on its structure and operation mechanism can potentially help in the creation of science medicines for depression   and radically new type of stress.

"Stress-related illness, such as depression and anxiety, poison the lives of one in four adults each year, - said study author Fiona Marshall. - But most people just do not realize that all these states are controlled by proteins in the brain, one of which is a CRF1" .

Protein reveals among other stress molecules in the hypothalamus - an area of ​​the brain that produces hormones that control the temperature, hunger and mood. When he "picks" one of the molecules, it makes other cells secrete hormones that cause stress and anxiety. (READ MORE)



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