Description overdue on 04/25/2014
- Latin name: Panavir
- ATC code: J05AX
- Active substance: Polysaccharides shoots Solanum tuberosum
- Manufacturer: Green Dubrava JSC (Russia)
- Composition
- Product form
- Pharmacological action
- Pharmacodynamics and pharmacokinetics
- Indications
- Contraindications
- Side effects
- Instructions for use (method and dosage)
- Overdose
- Cooperation
- Terms of sale
- Storage conditions
- Shelf life
- Cautions
- Analogs
- Babies
- With alcohol
- During pregnancy (and lactation)
- Reviews
- Price, where to buy
Composition
Composition solution for intravenous administration as follows: active ingredient - polysaccharides shoots Solanum tuberosum And also present in the composition Excipients - sodium chloride , Water for injections.
A preparation in the form of a gel It contains a similar active substance, and it contains glycerol . macrogol 400 . macrogol 4000 . Sodium hydroxide . 95% ethanol . lanthanum nitrate hexahydrate , And water as auxiliary substances.
Rectal suppositories contain the active substance polysaccharides shoots from Solanum tuberosum, also includes auxiliary substances: tallow or Confectionery . paraffin . emulsifier .
Vaginal candles Panavir are composed of similar active substance it contains also polyethylene 1500 (or macrogol 1500 ) polyethylene 400 (or macrogol 400 ).
Product form
Solution for injection - A colorless, odorless liquid, can sometimes have a light brown color. Contained in ampoules or in clear glass vials of 5 ml. Cardboard packet holds 2, 5 or 10 vials per blister polymer plastic.
Gel for local and external application issued in the form of a homogeneous white paste having a weakly pronounced odor. Available in a tube of aluminum at 3, 5, 10 or 30 grams, in a cardboard unit 1 has an aluminum tube.
Rectal suppositories may have a white or yellowish-white, cylindrical or tapered. Smell not have allowed the presence of inclusions of yellow-gray. Contained in a polymer blister 5 pieces. Sold in boxes of cardboard, which is embedded in one or two packages.
Pessaries are cylindrical or tapered. Color grayish-white, translucent. Injectable pack contains 5 suppositories, a pack of cardboard - one package.
Pharmacological action
Panavir - a drug with antiviral and immunomodulatory effects. It contains extract of shoots Solanum tuberosum. The main active ingredient is an extract hexose glycoside , Which includes mannose . rhamnose . galactose . arabinose . glucose . xylose and uronic acids .
During treatment Panavir marked intensification of development Interferon , An increase of nonspecific immunity.
The drug has an antiviral effect due to the ability of the active substance inhibits the synthesis of viral DNA in cells which have been infected with a virus.
Panavir at therapeutic doses normally tolerated without adverse effects observed (allergenic, mutagenic, teratogenic, carcinogenic, embryotoxic) in the body.
The drug also has analgesic and anti-inflammatory properties, it is determined regenerative effect, accelerates ulcer healing. It also has antipyretic activity. It is noted the ability of the drug to improve the function of the optic nerve and retina.
Pharmacodynamics and pharmacokinetics
When administered intravenously solution polysaccharides It can be detected in the blood after about five minutes after the drug was administered. Polysaccharides further captured cells reticuloendothelial system spleen and liver. Write mainly kidneys and lungs. The process is rapid excretion, polysaccharides exist in the urine and in the air exhaled by the person, in 20-30 minutes.
Indications
Solution for intravenous administration and rectal suppositories are used in the following diseases and conditions:
- herpesvirus infections (including herpes zoster , Relapsing genital herpes . ophthalmoherpes );
- secondary status Immunodeficiency Resulting from infectious diseases;
- cytomegalovirus infection (used to treat women with miscarriage, as well as in preparation for fertility treatments for patients with chronic viral infection).
As part of the comprehensive treatment:
- HPV infection ;
- ulcers in long nerubtsuyuschiesya duodenal ulcer and stomach ;
- tick borne encephalitis ;
- rheumatoid arthritis , Combined with herpesvirus infections ;
- chronic bacterial prostatitis ;
- flu and SARS .
Panavir gel used for skin diseases and diseases of the mucous membranes of infectious-inflammatory, which provoked the herpes simplex virus of the first and second type (including the genital herpes ).
Pessaries used in gynecology as part of a treatment for the development of genital herpes in women.
Contraindications
Contraindications in the application solution Panavir following:
- idiosyncrasy;
- are allergic to components of PM;
- during breast feeding;
- the child's age to 12 years.
Contraindications in the application of the gel Panavir following:
- idiosyncrasy and high sensitivity to the components of the drug;
- age 18 years.
Rectal and vaginal suppositories should not be taken in the following cases:
- Hypersensitivity;
- severe disease of the spleen and kidneys;
- pregnancy ;
- breast feeding;
- age 18 years.
Side effects
In the treatment solution for intravenous administration, and rectal suppositories may experience complications that are associated with high sensitivity to Panavir components, as well as individual intolerance to the drug.
If you use a cream for external use, you may be itching and redness in those areas where it is applied. However, these symptoms disappear quickly.
In the treatment of vaginal suppositories allergic reactions rarely occur.
If you manifest the above-mentioned or other side effects, it is necessary to suspend the treatment and consult a specialist.
Instructions for use (method and dosage)
Instructions on Panavir next. Injection solution performed intravenously, slowly jet. The therapeutic dose is 200 mg of active substance, i.e. a single solution vial or ampoule.
When treating herpesvirus infections and Tick-borne encephalitis The drug is used twice, with an interval equal to 48 or 24 hours. If there is such a need, the treatment can be repeated after one month.
When treating HPV and cytomegalovirus infections drug applied three times during the first week (the interval is 48 hours) and twice during the second week (interval is 72 hours).
During exacerbation peptic ulcer intravenous injections are conducted five times a day for ten days.
When treating rheumatoid arthritis Which combined with the herpes virus infection is carried out five injections intravenously, the range is 24-48 hours. The course is repeated as necessary after two months.
With Flu and SARS Two intravenous injection is carried out at intervals of 18 to 24 hours.
With chronic bacterial prostatitis held five intravenous injections every 48 hours.
Instructions on Gel Panavir Inlayta next. It is used topically, topically. Ointment applied thinly on those areas which were struck by the disease. The gel should be applied 5 times per day, the treatment lasts for 4-5 days. If necessary, the doctor can extend the treatment up to ten days.
Instructions for use Panavir (rectal suppositories) next. In the treatment of herpesvirus infections, and encephalitis used one suppository twice, with an interval of 48 or 24 hours. If it is necessary, repeat the treatment after a month.
In the treatment of influenza and SARS applied 1 suppository 24 hours over five days.
In the treatment of cytomegalovirus and human papillomavirus infections shows the use of one suppository three times in the first week (with the interval of 48 hours) and twice in the second week (time - 72 hours).
Suppositories (tablets) Vaginal applied vaginally. To enter you need as far as possible, in the supine position, legs bent. Within 5 days to 1 suppository is administered daily. Repeat the treatment only after consulting a doctor.
Instructions on Spray intimate Panavir It provided that prior to use is necessary to shake the vial and the application to keep it upright. Topically applied to the affected area by pressing on the valve 1-2 times. For intravaginal use a special nozzle.
Overdose
No cases of overdose. Preclinical studies indicate that the drug nizkotoksichen.
Cooperation
Panavir solution is not mixed in the same syringe with other parenteral medications.
Gel and Spray Panavir Intimacy can not be applied to the same area of skin at a time with any other topical preparations.
Terms of sale
The solution . rectal and vaginal suppositories prescription.
Gel Panavir dispensed in pharmacies without a prescription.
Storage conditions
Store the product must be in a dry, dark place at a temperature of 2-25 ° C. The drug should be protected from children.
Shelf life
Panavir can be stored for 3 years.
Cautions
Panavir intramuscularly administered only as directed by your doctor. If the solution is turbid, it is unsuitable for further use.
Treatment gel for topical use is recommended to start at the earliest stages of the disease, when the first of her symptoms. The gel does not apply to Ophthalmology . Do not allow contact with eyes.
There are no data about the effect of the drug on the ability to drive vehicles and work with complex mechanisms.
Analogs
Kagocel
Izoprinozin
Allokin Alpha
Ingavirin
Groprinosin
Amizon
Anaferon
Arbidol
By active substance Panavir structural analogs exist. Analogs selects physician, depending on the patient's diagnosis. In a similar mechanism of action of drugs have arbidol . Jodantipyrin . detoksopirol . Ferrovie . If the patient is assigned Panavir, cheaper counterparts, if necessary, may recommend a specialist.
Babies
Panavir solution can be used to treat children from the age of 12. Administered intravenously at a dose of 100 micrograms (one half of the ampoule).
With alcohol
Compatible with alcohol drug is not described in detail. However, experts do not recommend drinking alcohol during treatment Panavir as possible the occurrence of undesirable effects. In particular, improved toxicity for a series of compounded hypersensitivity reaction, increases the risk of other side effects.
During pregnancy and lactation
The solution Panavir appointed during pregnancy only if the potential benefit for the excess women of potential harm to the fetus. Pregnancy is cause for mandatory consultation with a physician before use of the drug.
Breastfeeding during treatment solution and rectal suppositories Panavir need to stop.
Reviews on Panavir
Reviews Panavir Inlayta As well as reviews of rectal suppositories suggest that therapeutic doses of the drug tolerated by normal and does not cause adverse side effects. People who were receiving drug treatment, and doctors note that intravenous injections Panavir exert effective influence after the first application for different diseases. However, applying the ampoule should be clearly adhere to the treatment regimen, which is prescribed by a doctor.
Reviews Panavir - gel against herpes also positive. According to patients, the drug, compared with other means of Herpes and from papillomas , Has been operating for a few days, eliminating the symptoms of herpes.
Members noted that the intimate spray Panavir Inlayta more simple and convenient to use than the cream or suppositories. It allows you to quickly get rid of the discomfort in the intimate zone and treat infectious diseases.
Panavir gel for warts It eliminates not in all cases. Members point out that it is more effective in the treatment.
Price Panavir where to buy
How much is Solution for intravenous administration Should specify, as the price Panavir / O (5 pcs.) In Moscow varies from 3,700 to 4,000 rubles. Buy ampoule (5 pcs. Pack) can be less subject to the availability of shares and discounts.
In Ukraine Panavir injections (5 vials) It can be purchased at the price of UAH 900-1200. If you want to make 2 injection pack (2 pcs.) Will cost 300 USD.
Cost gel Panavir 30 g on average 800-900 rubles. The cost of the gel 3 g on average 150 rubles. Ointment for herpes Panavir (3 g) in Ukraine srdnem costs from 50 to 60 UAH.
Cost Panavir Inlayta an average of 350-400 rubles. 1 bottle. Spray intimate in Ukraine can be purchased at the price of 220 USD.
Vaginal suppositories (tablets) Panavir costing on average 1700 rubles. 5 pieces per package.
Rectal suppositories will cost an average of 1800 rubles. 5 pieces per package.
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