Description overdue on 05/05/2014
- Latin name: Unidox Solutab
- ATC code: J01AA02
- Active substance: Doxycycline
- Manufacturer: BV Astellas Pharma Europe, Netherlands
- Composition
- Product form
- Pharmacological action
- Pharmacodynamics and pharmacokinetics
- Indications
- Contraindications
- Side effects
- Instructions for use JUnidoks Soljutab (method and dosage)
- Overdose
- Cooperation
- Terms of sale
- Storage conditions
- Shelf life
- Analogs
- With alcohol
- During pregnancy (and lactation)
- Reviews
- Price, where to buy
Composition
One tablet of a medicament comprising 0, 1 g of active ingredient of the antibiotic Doxycycline + Adjuvants ( MSC giproloza, saccharine, colloidal silica, lactose monohydrate, hypromellose, magnesium stearate ).
Product form
Round tablets, biconvex shape, a yellowish color, each tablet inscription 173.
Pharmacological action
Anti-infective . antibiotic groups tetracycline .
Pharmacodynamics and pharmacokinetics
JUnidoks Soljutab an antibiotic or not?
The active ingredient of the drug, doxycycline - Is an antibiotic from tetracycline group. It inhibits the vital functions of pathogenic bacteria, hitting ribosomal membranes in a cage. Prevents process occurs RNA synthesis Some organisms.
The drug active against such Gram-positive bacteria like, Streptococcus haemolyticus, Streptococcus viridans, Listeria spp, Streptococcus faecalis, Streptococcus pneumoniae, Staphylococcus aureus, Staphylococcus epidermidis.
The drug inhibits the ability to live Gram negative bacteria : Bacillus anthracis, Neisseria meningitidis, Brucella spp., Escherichia coli, Neisseria gonorrhoeae, Haemophilus influence, Clostridium spp., Salmonella spp., Pasteurella spp., Enterobacter spp., Entamoeba., Shigella spp. etc.
Also, using doxycycline treat diseases caused by Mycoplasma spp., Rickettsia spp., Chlamydia spp. and Spirochaeta spp .
Doxycycline is absorbed into GI . Within 2 hours after ingestion, it can be found in almost all body tissues (teeth, saliva), except cerebrospinal fluid . About half of the drug appears kidney The rest - through the gastrointestinal tract. Discovered in plasma the drug can be over 19 hours at a single administration, and 48 - during the course.
Indications
From what pills JUnidoks Soljutab?
The drug is prescribed in the treatment of diseases caused by microorganisms sensitive to doxycycline :
- ENT disease ( otitis, tonsillitis etc.);
- respiratory diseases ( pharyngitis, tracheitis, lung abscess, acute and chronic bronchitis );
- cystitis, prostatitis, pyelonephritis, urethritis, endometritis;
- IPP - At ureaplasma, syphilis, gonorrhea, chlamydia ;
- infection gastrointestinal tract - cholera, cholecystitis, gastroenterocolitis, diarrhea, yersiniosis ;
- trachoma, sepsis, peritonitis, osteomyelitis ;
- prevention malaria and postoperative zagnoeny.
What else treats JUnidoks Soljutab?
Yaws, rickettsial disease, legionellosis, Q fever, typhoid fever, Lyme disease is the first step, Rocky Mountain spotted fever, tularemia, actinomycosis, plague, malaria, psittacosis, leptospirosis, psittacosis, bartonellosis, anthrax, whooping cough, granulocytic ehrlichiosis, brucellosis, acne rash.
Contraindications
- children's age;
- liver and kidney disease;
- pregnancy and lactation;
- porphyria ;
- drug allergy for this group of antibiotics, or as part of the drug substance.
Side effects
- nausea, vomiting, loss of appetite, enterocolitis , Inflammation in the genital area, in connection with the activation of growth Candida fungus . stomatitis ;
- dermatitis, urticaria, anaphylaxis, pericarditis and erythema ;
- kidney and liver failure . albuminuria , Lack of potassium in the blood, increased levels of nitrogen in the blood plasma;
- anemia, porphyria, thrombocytopenia;
- tinnitus, hallucinations;
- brittleness of bones and teeth, discoloration of the enamel;
- hyperemia, anaphylactic shock, reduced blood pressure, tachycardia, shortness of breath .
Instructions for use JUnidoks Soljutab (method and dosage)
The duration of administration and dosage of the drug should be prescribed by a doctor, depending on the disease and its course. Tablets are swallowed whole or pulverized and mixed with water.
According to the instructions on JUnidoks Soljutab, adults appoint 0, 2 g Doxycycline per day (first day), for one or two doses. On subsequent days, the dosage may be reduced to 0, 1g, at the discretion of the attending physician.
With gonorrhea, syphilis and other serious FOD daily dose is usually 0, 3 g Tablets drink for 5-10 days.
Children (aged 8) when their weight is less than 50 kg, the calculation is made of the principle of 0, 04 g of antibiotic per 1 kg. Alternatively, half at the end of the day of the first administration.
Overdose
Symptoms of overdose are nausea , Headache, vomiting, diarrhea . Treatment - according to the developed symptoms gastric lavage . chelators .
Cooperation
Reception, together with magnesium-containing laxatives, iron compounds, sodium hydrogencarbonate, calcium, magnesium and aluminum It should be no less than 3 hours after the antibiotic.
The drug reduces the effectiveness of a number of antibiotics Penicillin and cephalosporin .
The drug may cause a decrease prothrombin index and effectiveness hormonal contraceptives . Also, while admission to Retinol may be an increase intracranial pressure .
The concentration of doxycycline in the blood drop, if you combine the drug with ethanol, rifampicin, phenytoin, barbiturates and carbamazepine .
Terms of sale
It requires a prescription.
Storage conditions
In a dark, cool, the children, temperature 15-25 degrees.
Shelf life
5 years.
Analogs JUnidoks Soljutab
Oletetrin
Doxycycline
The most common counterparts: vibramitsin d, doksibene hydrochloride, doxycycline, tetracycline hydrochloride, Doxa m-ratiopharm, doxycycline, tigatsil . Price analogues differs significantly from the original, it is often below.
Doxycycline or JUnidoks Soljutab - which is better?
The main difference between drugs is the fact that JUnidoks not so much effect on the stomach and does not cause side effects characteristic of doxycycline ( stomach ulcers, gastritis ). Absorption of the active ingredient occurs in the intestine and nearly 100% of the drug absorbed by the body. The only advantage of doxycycline is its very low cost, compared with the original.
What is different from JUnidoks JUnidoks Soljutab?
Console " soljutab "In the name of the drug means that the tablet can be crushed and dissolved in water to prepare suspension for reception. This method of use of medications is preferable for children.
With alcohol
JUnidoks Soljutab better and alcohol do not mix. When antibiotics alcohol concentration in the blood plasma of the first reduced, and accordingly reduces the effectiveness of the means.
During pregnancy and lactation
The degree of penetration of the placenta and the mixing of milk is too high. When pregnancy is not usually prescribed.
Reviews JUnidoks Soljutab
Reviews in gynecology . The drug has good reviews in the treatment of gynecological diseases, such as Chlamydia . Patients who funds designated for chlamydia, there is a slight antibiotic tolerance and efficacy. Although sometimes there are side effects such as headaches and disorders of the digestive system.
Reviews from using ureaplasmas too good, many are of the opinion, the drug is almost the only effective way to get rid of the disease.
Reviews on JUnidoks Soljutab acne . Sometimes acne treatment dermatologist may prescribe antibiotics. Most patients of acne medication helps, but then there are other problems caused by the side effects of the drug. Many compliance with therapeutic diet helped better than to take antibiotics.
Price JUnidoks Soljutab where to buy
The average price of pellets in Ukraine is UAH 80 for 10 pieces. How much does the medicine in Kiev? The price doxycycline 100 mg (10 tablets) contained in the product to be about 90 USD. The cost of the same amount of the drug in Kharkov will be about 115 USD.
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