Description overdue on 08/22/2014
- Latin name: Procto-Glyvenol
- ATC code: C05AX03
- Active substance: Tribenozid + lidocaine (Tribenoside + Lidocaine)
- Manufacturer: Novartis Consumer Health (Switzerland), Novartis Pharma SaS (France)
- Composition
- Product form
- Pharmacological action
- Pharmacodynamics and pharmacokinetics
- Indications
- Contraindications
- Side effects
- Instructions on Procto-Glivenol (method and dosage)
- Overdose
- Cooperation
- Terms of sale
- Storage conditions
- Shelf life
- Analogs
- During pregnancy (and lactation)
- Reviews
- Price, where to buy
Composition
As part of the same Candles contained 400 mg tribenozida and 40 mg lidocaine .
As part of 100 grams cream contains 5 grams tribenozida 2 g lidocaine + Auxiliaries.
Product form
The drug is produced in the form rectal suppositories . White oblong candles produced in blister 5shtuk in blister packs of 2.
And also in the form of a white, homogeneous, opaque cream Having a peculiar smell. The tube with a capacity of 30 grams.
Pharmacological action
Protivogemorroidalnoe, analgesic (local).
Pharmacodynamics and pharmacokinetics
Tribenozid and Lidocaine in combination reduce inflammation and pain affected area.
Active ingredient tribenozid It reduces the permeability of blood vessels, reduces venous stasis. The substance has the ability to inhibit the activity serotonin, histamine and bradykinin , Without affecting the hormones norepinephrine and e pinefrin . The drug eliminates congestion in the veins, reduces pathologically increased vascular permeability. Tribenozid relieves inflammation due to its property to inhibit the neurotransmitters, analgesics, relieves swelling. Ability Platelet to Adhesion also decreases.
Lidocaine It has a strong analgesic effect. It blocks Sodium Channels , Stabilizes cell membranes. In this regard, the generation and conduction of nerve impulses is slowed.
Within two hours after the administration of the candle reaches its maximum drug concentration in the blood. Bioavailability amounts to about 30-40%.
After applying the cream of 20% ( tribenozid ) To 50% ( Lidocaine ) Active substances into the bloodstream. When applying the ointment to the mucosal, its efficiency is improved, the active ingredients are absorbed more effectively.
The drug undergoes a conversion reaction in other substances in the liver, which are then excreted through the kidneys. Part of lidocaine appears in its original form.
Indications
Candles and ointment Procto-Glivenol indicated for the topical treatment Hemorrhoids Internal and external. Generally, in an integrated treatment.
Contraindications
The drug is not prescribed to children. Not recommended during reception first trimester or allergies on any of the components of the means.
Side effects
Occasionally you may experience discomfort immediately after administration or application means the mucous. Also available hives . contact dermatitis . hypercatharsis .
There have been rare cases of angioedema . face edema . bronchospasm , Side effects of the cardiovascular system.
Instructions on Procto-Glivenol (method and dosage)
Rectal. Candles Procto-Glivenol, instructions for use
Before use, free from the packaging suppositories and lightly moistened with water. Gently introduce a candle, lying on his right side, pinning his left leg to his chest. 1 suppository use, two times a day. If further treatment dosage can be reduced to a single candle.
Duration of the course is determined by the attending physician.
Instruction in the ointment
On the day performed by two applications of ointment, one - in the morning, the second - in the evening. The daily dosage can be reduced to a single overnight.
If there is a need ( hemorrhoids arranged inside) should use a special nozzle for applying cream. On average, it takes about one applique grams of ointment.
Overdose
Overdose cases are not registered. However, if the candles or cream got inside, should be made gastric lavage Take chelators .
Cooperation
It is not known whether the interaction of the drug with other agents.
Terms of sale
The presence of a prescription is not required.
Storage conditions
In a cool place, away from children.
Shelf life
5 years.
Analogs
Anuzol
Posterisan
Posterisan Forte
Bezornil
Glivenol
Fitoval
Proktozan
Gepazolon
Gepatrombin F
Proctosedyl
Analogues of the drug are: Anuzol . About Relief . Bezornil . Betiol . Pileks . Neo Proktozan . Proctosedyl . Relief . Proktan . Gemorron . Belladonna Extract . Aurobin . Proktozan .
During pregnancy and lactation
Procto-Glivenol at pregnancy should be used with caution. During breast-feeding can receive the drug after consultation with a physician.
During the first trimester of pregnancy should be particularly careful.
Reviews Procto-Glivenole
Reviews candlelight Procto-Glivenol
The drug has good reviews. Within a few days the drug relieves the discomfort of burning, itching and pain. It helps with anal fissures, with external and internal hemorrhoids do not cause allergy .
Reviews of Cream
Many prefer the ointment, because they believe that the spark will come to an end, and the cream is much easier to use and more convenient, more economical. Tool quickly and permanently removes the unpleasant symptoms of hemorrhoids and accelerates the healing process.
Price Procto-Glivenola where to buy
Cost candles Procto-Glivenol It is about 400 rubles.
How much does the ointment? Cost Procto cream-Glivenol - About 550 rubles per 30 grams.
No comments:
Post a Comment