Sunday, September 17, 2017

Permanganic acid

Description overdue on 14.02.2012

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 Permanganic acid  Antiseptic . Atomic oxygen is released upon contact of the drug with organic substances. When restoring drug oxide is formed, which is in contact with the protein complex is formed albuminates . They have tanning, cauterizing, deodorizing and irritating. Potassium permanganate is effective for ulcers, burn injuries. Potassium permanganate is able to neutralize certain poisons, which allows its use in the nutritional diseases, poisonings. The medicament has gematotoksicheskim action It leads to the development of methemoglobinemia   if swallowed. Available in powder form.

Indications and contraindications:

Potassium permanganate is used for infected wounds, burns, skin ulcers. When angina, infectious and inflammatory diseases of the oropharynx, oral potassium permanganate is used for rinsing. In urology and gynecology is used for irrigation, washing (if urethritis . obesity ). The ingestion of nicotine, aconitine, morphine alkaloids, in poisoning by phosphorus, hydrocyanic acid, potassium permanganate washed quinine stomach. When eyes are affected by poisonous insects are washed with a weak solution of the drug eyes. Potassium permanganate is contraindicated in case of intolerance.


Side effects and overdose:

Application of a concentrated solution causes burns. If overdose is marked sharp pain along the esophagus, in the mouth, diarrhea, vomiting. The mucosa of the pharynx, oral cavity becomes purple, may develop laryngeal edema, burn shock, mechanical asphyxia , Seizures, hepatopathy, nephropathy, hemorrhagic colitis , Symptoms of Parkinson's disease, motor excitation. With reduced gastric acidity develops shortness of breath, cyanosis, methemoglobinemia. In overdose antidote is ascorbic acid, methylene blue, cyanocobalamin, pyridoxine.

Mode of application:

Permanganic acid is used for washing (solution concentration 0, 1-0, 5%), lubricating (concentration 2-5%), douching (concentration of 0, 02-0, 1%), topically.

Drug Interactions:

Potassium permanganate is chemically incompatible with sugar, charcoal, tannin, easily oxidized substances (risk of explosion).

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