Wednesday, September 13, 2017

Nise

Description overdue on 29.08.2012

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 Nise  The anti-inflammatory drug from the group of NSAIDs. The active component is Nimesulide . The basic substance has antipyretic, analgesic, and antiplatelet pronounced anti-inflammatory properties. The main difference between the drug Nise other NSAIDs is the possibility of a selective, selective suppression of cyclooxygenase-2 inhibition development prostaglandins   in the inflammatory foci. Nayz available in tablet dosage form, a gel, granules, suspensions.

Indications:

Nise tablets prescribed for ankylosing spondylitis , Bursitis, tenosynovitis, osteoarthritis, rheumatoid arthritis, tendonitis, synovitis, with pain syndrome (post-traumatic pain, tuberculosis), neuralgia, pain in the spine, inflammation of soft tissue traumatic nature in the locomotor system, with feverish syndrome , Followed by infectious and inflammatory diseases. Nise gel administered topically for the treatment of these diseases.

Contraindications:

Nise tablets do not apply to the erosive and ulcerative lesions of the digestive system , Intolerance of nimesulide, in renal failure, "Aspirin" asthma , Breastfeeding, liver failure, pregnancy, children under 12 years. With diabetes   Type 2, arterial hypertension, heart failure Nise used with caution. Nise gel is applied with infectious lesions of the skin, the epidermis is damaged.


Side effect:

Tablet form of the drug may cause Nise stomachalgia , Diarrhea, nausea, dizziness, heartburn Allergic reactions, fluid retention, headaches, agranulocytosis , Anemia, hematuria, increased levels of liver enzymes, thrombocytopenia . Local reactions at the application of the external forms of the drug Nise: transient changes in skin color, skin rash, irritation, itching, flaking.

Mode of application:

Nise Inside, after meal 1 tablet (equivalent to 100 mg). The granulate was diluted in 100 ml of water (1 bag) to twice a day. Each time necessary to prepare a fresh solution. For children produced slurry administered 2-3 times per day per 1, 5 mg / kg. The gel can be applied up to 4 times a day, 3 cm of the gel is applied to intact skin uniformly, without rubbing. The frequency of application of the gel and the quantity are selected individually depending on the patient's response and the area of ​​the treated skin area.

Special instructions:

Long-term treatment with nimesulide requires periodic monitoring of the functioning of the renal system. Nise Gel should not be applied to broken skin, conjunctiva and mucous membranes. Do not cover the treated areas occlusive dressings.

Drug Interactions:

Myelotoxic medicines have contributed to increasing severity gematotoksichnosti   drug Nise.

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