Lidocaine

Description overdue on 19.08.2011

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Lidocaine - is one of the most effective drugs that eliminate ventricular arrhythmia and tachycardia. It is used for the treatment and for the prevention of ventricular rhythm disorders, and ventricular fibrillation sufferers myocardial infarction . Lidocaine has mestnoobezbalivayuschuyu Activity .

Indications:

This medication is prescribed for Ventricular tachycardia   and arrythmia .

Mode of application:

In order to establish a therapeutic concentration in the blood, it is necessary to enter the drug by slow intravenous injection - 0 001 grams per kilogram of body weight. Already in the first minute after administration of the drug effect occurs, which is very short. For this reason, followed immediately begin to infuse lidocaine intravenous drip at about 0 and 002 g per minute. Due to the rapid drug biotransformation in the liver for half its concentration in the blood falls below the therapeutic level, so ten minutes after the first administration of lidocaine administered repeatedly.

Side effects:

It is recommended to use a low concentration of lidocaine. In the case of an overdose the following symptoms may occur: muscle tremors, decreased blood pressure, vomiting, nausea, pallor. Unless intoxication   severe, there may be convulsions, depression of the respiratory center, vascular collapse . hypotension .

Contraindications:

Lidocaine is contraindicated in severe muscle weakness. His caution should be used in cardiovascular deficiencies, diseases of the kidneys and liver.

Interaction with other drugs:

When used in parallel with this medication such as the drugs dizopiramid . procainamide . quinidine   rarely may develop ventricular fibrillation and AV-blockade. Cardiodepressive action Lidocaine increases phenytoin . Hallucinations   (mental disorders) may be caused by the simultaneous administration of the drug with procaine. In addition, lidocaine enhances the action of drugs that cause blockage of neuromuscular transmission. Ethanol enhances the inhibitory effect of the drug on the respiratory system.

The following drugs increase the concentration in the blood Lidocaine: nortriptyline, imipramine, amitriptyline , Disopyramide, quinidine, bupivacaine, pethidine, propranolol , Cimetidine, chlorpromazine .

Overdose:

In case of overdose there may be some reaction from the cardiovascular (bradycardia, tachycardia, collapse, drop in blood pressure) and central nervous ( disorientation , Drowsiness, convulsions, tinnitus, anxiety, headache, "flies" before his eyes, neurotic reaction) systems.

Special instructions:

Unlike intravenous infusion of lidocaine in several minutes to cross the placenta, so pregnancy drug can be used alone in therapeutic doses. It is not known whether this medicine is found in breast milk, so breast-feeding should be very careful.

Patients with circulatory failure, liver dysfunction, kidney failure, epilepsy, and hypotension, the dose should be reduced.

Lidocaine Spray should not get into the eyes and contact with them and avoid its penetration into the respiratory tract. Special care is required in the application of the throat. You must also keep in mind that the swallowing reflex in children occur more frequently than in adults.

If the side effects of lidocaine do not cause you discomfort, the constraints to control mechanisms and traffic management are not present.