Description overdue on 08/20/2014
- Latin name: Aqua veratri
- ATC code: R03AH
- Active substance: Hellebore Lobel rhizomes and roots of tincture (Veratri lobeliani rhizomatum cum radicibus tinctura)
- Manufacturer: Red Star, Ukraine
- Composition
- Product form
- Pharmacological action
- Pharmacodynamics and pharmacokinetics
- Indications
- Contraindications
- Side effects
- Instructions on Water hellebore: how to use and dosing regimen
- Overdose
- Cooperation
- Terms of sale
- Storage conditions
- Shelf life
- Cautions
- Hellebore water use in pediatrics
- During pregnancy (and lactation)
- Reviews
- Price, where to buy
Composition
In 100 ml of water contained in the hellebore 50/50 alcoholate rhizomes and roots of hellebore ordinary (Veratrum Lobellianum Bernh) and purified water (Aquae Purificate).
Alcohol tincture of hellebore receive, insisting its roots and rhizomes of 70% ethanol.
Product form
Hellebore water is discharged in the form of a solution for topical use in dark glass bottles with screw neck. The capacity of one bottle - 40 or 100 ml.
The solution is a liquid brownish yellow cloudy or precipitate, but by shaking the vial passes into the turbid.
Pharmacological action
The drug belongs to the pharmacological group antiparasitic means insecticides and repellents Affecting ectoparasites (in particular, bloodsucking arthropods - lice . mosquitoes . mites ).
Pharmacodynamics and pharmacokinetics
Hellebore water is used as a protivopedikuleznogo (antiparasitic) agents. The drug has a pronounced neurotoxic against adult lice .
The pharmacological properties of the solution are determined by the properties of its composition as an active ingredient of hellebore - perennial herbaceous poison of the lily family.
All parts hellebore contain in its composition Alkaloids from the group tsiklopentanpergidrofenantrena and glycoalkaloids (steroidal alkaloids), which are naturally occurring compounds that combine the basic properties alkaloids and steroid saponins .
Thus, the grass in their contained approximately 0, 55, rhizomes - 1, 3, and the roots - 2 to 4%. From the roots and rhizomes of release alkaloid iervin (aminoalcohol) and g likoalkaloid psevdoiervin (chloroform).
Moreover in the summertime time of the year the concentration of alkaloids the plant is sharply reduced, and in the spring - rises, so it is in the spring months is considered the most poisonous hellebore.
The basic structural element of the studied alkaloids hellebore are alkaminy (aminoalcohols or aminoalkogoli) which are secondary and tertiary bases including piperidine ring .
In medical practice, drugs hellebore is used as an effective tool against ectoparasites , I.e. parasites that live on the outer surface of the body and organs.
Used as an external agent solution has a strong hellebore antiscabietic action . In veterinary practice, the broth made from the roots and rhizomes of hellebore, as prescribed means of improving digestion, and as an emetic.
Experiments showed that the complex contained in ordinary veratrum of alkaloids , Also contributes to the decline in blood pressure while simultaneously increasing the amplitude heart rate It provokes irritation endings sensory nerve , Is highly sneezing and coughing .
When taken orally causes vomiting . In foreign countries, isolated from veratrum alkaloids are used as antihypertensive .
In particular, sustained hypotensive action has a part of the plant protoveratrin : Substance reduces performance systolic and diastolic pressure Provokes bradycardia Expansion of the lumen of blood vessels, reduces the rate of blood flow minute volume.
In addition, it reduces diuresis and to some extent it provides hypothermic effect . However, the breadth of therapeutic action protoveratrina is low, so the best effect of adoption is celebrated in the early (I-II) stages hypertensive disease . Also, it is sometimes used in eclampsia and preeclampsia .
Part of the ordinary hellebore veratramin reduces performance Blood Pressure and heart rate , Providing blocking action on pressoretseptory carotid sinus It reduces the excitability vasomotor center .
Germitrin and neogermitrin have a stimulating effect on the vascular baroreceptors (sensory nerve endings in the blood vessels, which perceive changes blood pressure reflex and its level is adjusted), and, unlike protoveratrina , Opposite, raise excitability vasomotor center .
Widespread use alkaloids of hellebore difficult because of-because of their high Toxicity .
Formulations in which the plant acts as the active substance, used solely as an external agent. They are effective as antifungal . irritant and painkiller .
Against the background of hellebore significantly increased skeletal muscle tone, expanding vessels of the circulatory system Is excited nervous system .
Its products are used in pain syndrome s, which are accompanied by neuralgia . myositis . arthritis , Bouts of gout . rheumatism and various diseases of the oporno-impellent device .
Alcohol solution is used externally by rubbing the scalp, in the Dandruff and for Hair Growth . Also, effectively the use of hellebore of water from lice : Means a detrimental effect on the state of smooth muscle of the intestinal tract of parasites and their reproductive system, causing them to lose their ability to feed and reproduce.
In folk medicine, preparation is used and for struggle against alcohol addiction .
As an anti- Alcoholism hellebore water is used orally (despite the ban on the use of this method of instruction and official disapproval of Medicine).
The mechanism of action of the drug is based on the ability of of hellebore to provoke the a strong intoxication the body when taking her drugs inside. The infusion is mixed without the knowledge of the patient to alcoholic beverages, with the result that a person is exposed to poison.
Alkaloids of hellebore ( protoveratrin , Jumpy and others.) Have a stimulating effect on the first central nervous system And then blocking it, as manifested by the following symptoms:
- severe vomiting;
- diarrhea ;
- general stimulation of the body;
- deterioration in general well-being;
- A steady increase in muscle tone, which is replaced by spasms;
- acute heart failure .
Almost 100% of the patient required hospitalization and medical care. This method of application hellebore water suggests that after experiencing an alcoholic, believing that the cause is alcohol poisoning, all will experience an aversion to it.
However, such treatment Alcoholism It causes skepticism and opposition from physicians. Firstly, the human body can not cope with the load, and all end fatal .
This is due to the fact that contained in the hellebore protoveratrin extremely adversely affects the Digestive and circulatory system As well as Head of Ministry of Health city
Secondly, reviews about the application of hellebore of water from Alcoholism testify about what fully rebounding after treatment, most suffering from alcohol addiction return to their addiction.
Ex external application contained in ordinary hellebore alkaloid s practically it is not soaked and do not render resorptive action (or last very slightly).
Prolonged use of hellebore water or excessive rubbing active drug in the skin can lead to the penetration of the latter into the deeper tissue and cause the development of various kinds resorptive effects (in particular, intoxication ).
Indications
The indications for the use of hellebore water are:
- pediculosis scalp;
- pediculosis pubis.
Contraindications
The drug is contraindicated in:
- people who have an increased individual sensitivity to its member components;
- at presence of the infected damage an integument;
- pregnant and lactating women;
- children under the age of 30 months.
Side effects
In rare cases hellebore water can provoke development of local allergic reactions Which manifest themselves in the form of:
- itching;
- burning sensations;
- tingling;
- tingling;
- erythema (redness) at the site of the drug.
If you accidentally receiving funds into possible symptoms of poisoning:
- nausea;
- diarrhea;
- dry mouth;
- thirst;
- severe headaches;
- podlozhechkovoy pain in the area.
In severe cases may experience arrhythmia and contraction frequency of the heart muscle Which are often accompanied by slow pulse . Sometimes affected nervous system , As evidenced by:
- convulsions;
- increased arousal;
- visual disturbances;
- loss of consciousness.
Often the only signs toxic alkaloids hellebore are dyspeptic disorders and a sharp slow pulse with falling figures Blood Pressure (which is due to excitation vagus nerve ).
Instructions on Water hellebore: how to use and dosing regimen
As a means of lice hellebore water is used as an external agent. Before applying the vial vigorously shaken, after which pre-wearing rubber gloves, the solution is applied to wet hair in amounts necessary to wet the hair and the skin underneath.
To effect was maximum, hellebore guide recommends applying water evenly over the entire surface of the head, not forgetting about the processing sites located in the occipital region, and behind the ears.
The head scarf tie and leave the drug on the hair for about twenty minutes or half an hour. The hair is then thoroughly washed with the shampoo under warm tap water and combed well with toothed comb to remove dead insects by treatment.
Allowed reprocessing head with an interval of 24 hours. In secondary infestation procedure is repeated not earlier than seven to ten days.
A side effect of hair treatment lice and nits is the effect on hair. After treatment of their condition significantly improved, the hair becomes more manageable, shiny and silky.
Also, improved and condition of the scalp:
- normalizes its fat content;
- destroyed pathogens (including fungi, provoking the appearance Dandruff );
- increases tone of blood vessels head;
- is improved inflow of of blood to the hair follicles (as a consequence of this hair follicles is much better supplied oxygen and necessary microelements ).
Application for hair growth presupposes infliction hellebore water on hair approximately once in week. If you have bald patches, as well as people who alopecia It was the consequence of radiation therapy It is allowed to wipe the hairless areas of the skin head through the day.
The drug is applied by sponges, pads or discs made of cotton, brush, brushes. Some gain hellebore water in a medical syringe, spread evenly over the middle and then comb the hair.
And allowed just take a plastic bottle with holes in the tube and thus the means to put on the hair roots.
What is hellebore water, also know people who suffer from alcohol addiction and their relatives. Ingestion of the drug, along with a portion alcohol It allows you to trigger symptoms intoxication organism in which alcoholic It is likely to be to blame drink.
After some medical assistance and recovery of the body can be observed steady aversion to alcohol. However, such "treatment" is quite dangerous, because often leads to serious consequences for human health and can even cause death.
If, however, other methods have been ineffective, and the use of hellebore is considered as the only panacea, it should be remembered that the water from the pharmacy hellebore Alcoholism not used because of the high risk of side reactions. Instead, traditional medicine recommends to prepare a decoction of the root plant. But when it is used by Alcoholism , The dosage should be followed very strictly.
Recipe of decoction roots and rhizomes of of hellebore the next: 1 teaspoon of raw materials (dry shredded roots of the plant) is poured 50 grams of of boiling water and insist in a for one hour, after which strain off through a a gauze otrez and are cleaned in a cool place.
The resulting broth is allowed to keep no more than five days. Use it well, adding a pipette three times a day for two drops (no more!) In the food and drinks (non alcoholic).
In those days, when the patient do not consume of liquor, a decoction in food do not add, to correctly work out a emetic and a laxative effects of . If the expected therapeutic effect of the agent is not observed, the dose is gradually increased one drop a day (but no more than fifteen drops).
If even higher doses are ineffective, should stop treatment and seek professional help.
Overdose
Hellebore - it is a very toxic plant. Enteral intake it in an amount of 1 gram, leading to death.
Prolonged treatment, as well as the systematic excess of recommended doses of instructions contained in the hellebore water Alkaloids may trigger the development of resorptive effects Which manifest themselves in the form of:
- nausea;
- severe vomiting;
- a sharp decrease Blood Pressure ;
- pronounced, which is accompanied by a sharp increase in the amount of secreted saliva and sweat, loose stools . pupillary constriction , Slowing Heart Rate , Fall in Blood Pressure . asthmatic breathing ;
- inhibition activity heart muscle .
Contact with systemic circulation large number of alkaloids can provoke a stop hearts . By this reason peroral use of the drug inadmissible.
For first aid in case of accidental ingestion of water affected hellebore appoint:
- gastric lavage solutions tannin Which are characterized by their tanning properties;
- oral suspension Activated Carbon or white clay ;
- reception antigas drugs ;
- saline laxatives ;
- Irrigation two percent solution novocaine (if amazed mucous membranes).
Treatment specific. Therapy involves prescriptions holinoliticheskogo (intravenously administered to 0, 1% solution atropine ), Drugs that improve the function hearts and vascular system As well as a means of normalizing the function gastrointestinal tract .
Cooperation
Interaction with other medicinal means is not revealed.
Terms of sale
Hellebore water may be used as a non-prescription drug.
Storage conditions
The drug may be stored in a dry dark place. The optimal temperature - not higher than 20 ° C.
Since hellebore water toxic if swallowed, it is stored as toxic substance - Out of the reach of children.
Shelf life
Means retains its pharmacological properties within 2-x years. After this period, it is not permitted to use.
Cautions
The drug is allowed to be applied only on intact skin.
Due to the high probability of resorptive action when you use it to avoid contact with eyes, mucous membranes, wound, burn or irritated surface, as well as in the mouth (by ingestion stomach and bloodstream the drug acts as a powerful poison ).
After applying hellebore water, wash hands with soap and water.
As a preventive measure to avoid recontamination by parasites Simultaneously with the treatment should be disinfected clothes, bed clothes.
Using the hellebore of water in the of Pediatrics
The drug may not be used to treat children who are under 30 months. Use in children under 12 years old are allowed on prescription.
Pregnancy and lactation
Clinical studies regarding the use of hellebore water pregnant and nursing women not conducted.
For this reason, drug treatment pregnant appoint exclusively in the those cases, when advantage for mother exceeds potential risks for the future of of the child. Treatment is carried out under strict indications and under the constant supervision of a doctor.
If you want the appointment of hellebore water lactating women Then the period of treatment was stopped breastfeeding.
Reviews of hellebore water
Reviews of water with hellebore lice suggest that, despite its low price, it is a very powerful tool and effectively kills not only adults, but their larvae.
The average score of the drug at various forums and sites reviews - 4, 5 points on a scale. Perhaps the only drawback hellebore water many consider only side effects that occur after its application - namely, tingling and slight burning in areas of application.
The advantages also include:
- low cost of funds;
- high efficiency in the fight against lice (some reviews suggest that hellebore water is often more effective than its more expensive counterparts);
- efficiency in the fight against Scabies .
In addition, the drug established himself as a inexpensive and deserving the trust of a means of for hair growth and of strengthening them. Irritating the scalp, hellebore water increases vascular tone , Thus stimulating bloodstream and improve the supply hair follicles and a sufficient supply of oxygen.
As a means of Alcoholism hellebore water has earned itself quite mixed reviews. Some people say its effectiveness, however, most health care providers agree that the risks to the patient exceeds the possible effect of the treatment.
For this reason, before the use of the drug should carefully weigh the "pros" and "cons", as well as consult with a specialist.
Price hellebore water
The drug belongs to the category of available drugs: price hellebore water in Ukraine ranges from 18 to 28 hryvnia.
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