Description overdue on 05/14/2014
- Latin name: Macmiror
- ATC code: G01AX05
- Active substance: Nifuratel (Nifuratel)
- Manufacturer: Poli Industria Chimica (Italy)
- Composition
- Product form
- Pharmacological action
- Pharmacodynamics and pharmacokinetics
- Indications
- Contraindications
- Side effects
- Instructions on the Makmiror (Method and dosage)
- Overdose
- Cooperation
- Terms of sale
- Storage conditions
- Shelf life
- Analogs
- With alcohol
- During pregnancy (and lactation)
- Reviews
- Price, where to buy
Composition
The tablet of the drug contains the active substance ( nifuratel ) - 0, 2 + grams adjuvants ( talc, starch, magnesium stearate, polyethylene glycol, gelatin, magnesium carbonate, gum, wax, titanium dioxide, sucrose ).
Product form
Convex white tablets in a coating of sugar. Package of 20 pieces.
Pharmacological action
Antibacterial .
Pharmacodynamics and pharmacokinetics
Makmiror an antibiotic or not?
The active substance from the group nitrofurans . Exhibits antibacterial activity in relation Gram-positive and -negative bacteria. It is also good antifungal and antiprotozoan agent.
It inhibits the processes of division and multiplication amoebas, lamblia and other protozoa . Aerobic and anaerobic .
Sensitive to the preparation: Papiliobacter . Enterococcus faecalis, Helicobacter pylori, Enterococcus faecium, Escherichia coli, Trichomonas vaginalis, Atopobium vaginae, Bacillus subtilis, Shigella flexneri , Various strains Salmonella, Enterobacter sph., Citrobacter spp., Staphylococcus aureus, Rettgerella spp., Budvicia aquatic, Poliindustria chimica.
The drug has the ability to metabolizirovatsya muscle and liver tissues, highlight the milk during breastfeeding, held gemoplatsentarny barrier. About half nitrofuratela It passes through the excretory system (mainly - the kidney).
Indications
- disease gastrointestinal tract Caused by bacteria Helicobacter pylori ;
- Giardia and Amoeba in the gut;
- pyelonephritis, cystitis and t. d., if the disease is caused by microorganisms sensitive to nitrofurans ;
- vaginitis, vulvovaginitis .
Contraindications
Drug allergies .
Side effects
Nausea, vomiting, allergic rashes on the skin.
Instructions on Makmiror (method and dosage)
Duration of treatment and the desired the dosage of should appoint the doctor.
According to the instructions for use Makmiror:
Diseases of the digestive tract : Adults prescribed 2-3 tablets 2-3 times daily, a course of treatment is from 7 to 10 days, depending on the disease.
For young daily dose - 15 mg per kg weight. Its chop up to 2-3 hours. The course - 7-10 days.
Urinary tract infections : Daily dosage for an adult - 0 3-0 4g a day, after meals. The course the treatment of from 7 to 14 days. Children older than 6 years - 15 mg per kg body weight.
When vulvovaginitah STI Adults appoint 3 tablets a day, divided into 3 admission. For complex treatment additionally appoint a special cream for men and women.
For children older than 10 years, the daily dose is calculated from the principle of 0, 01 grams per kg body weight and divided into 2 doses per day.
Overdose
Currently no cases have been reported.
Cooperation
Virtually no interaction.
At simultaneous reception and Makmiror Nystatin It increases the effectiveness of the latter.
Terms of sale
It requires a prescription.
Storage conditions
A dark, dry place, the temperature - no more than 25 degrees.
Shelf life
5 years.
Analogs Makmiror
Laktozhinal
Dafnedzhin
Furazolidone
Atsilakt
The analogue in tablets : furazolidon .
Analogs ointments and candles : Makmiror complex, vokadin, Hexicon, osarbon, chlorhexidine, betadine, ekovag, yodoksid .
Often, price analogues strongly differs from the original.
With alcohol
Alcohol and drug intake is better not to combine, may increase adverse reactions.
Makmiror during pregnancy and lactation
Assign medicine can only be a doctor, because the active ingredient is easily overcome blood-placenta barrier . However appoint Makmiror Complex during pregnancy frequently.
At reception Nifuratel , The drug passes into breast milk. Feeding would have to stop.
Reviews Makmiror
Reviews on the forums are basically good. Good help from IPP Does not provide the liver complications, side effects are rare. Many write that miraculous medicine, it helps if the liver disease, there are other means and reception is difficult.
Reviews tablets at giardiasis It is also positive, although there are complaints of headache and nausea. Doctors often prescribe medication to children from Giardia. Parents celebrate its effectiveness.
Price Makmiror (Where to buy)
The average price of tablets Makmiror in Russia - 539 rubles for 10 tablets of 400 mg. The cost of drugs in Novosibirsk - 520 rubles per 20 pieces. Buy pills in Moscow can be for 600 rubles.
No comments:
Post a Comment