Description overdue on 06/09/2014
- Latin name: Reaferon-EU-Lipint
- ATC code: L03AB04
- Active substance: Interferon alfa-2a (Interferon alfa-2a)
- Manufacturer: Vector-Medica JSC, Russia
- Composition
- Product form
- Pharmacological action
- Pharmacodynamics and pharmacokinetics
- Indications
- Contraindications
- Side effects
- Instructions for use (method and dosage)
- Overdose
- Cooperation
- Terms of sale
- Storage conditions
- Shelf life
- Analogs
- Babies
- With alcohol
- During pregnancy (and lactation)
- Reviews
- Price, where to buy
Composition
One vial contains formulation ME 250000, 500000 ME, ME 1 million active ingredient.
Excipients:
- 8, 01 mg - sodium chloride;
- 4, 52 mg - hydrogen phosphate dodecahydrate sodium;
- 0, 56 mg - sodium dihydrogen phosphate dihydrate;
- 41, 18 mg - lecithin or lipoid C100;
- 0, 56 mg - vitamin E;
- 4, 53 mg - cholesterol;
- 91, 34 mg - lactose.
Product form
Packaging containing 5 or 6 vials of different dosages of 1 ml.
Pharmacological action
Antitumor, antiviral, immunomodulatory.
Pharmacodynamics and pharmacokinetics
IFN-EU-Lipint intended for internal administration. Oral administration of the drug is particularly important in the treatment of pediatric patients.
From degradation of the drug in humans, it protects liposome shell It also allows the passage through the digestive tract of interferon unscathed. Once in the liver, the drug is absorbed into the bloodstream, which is slowly released.
When receiving the contents of the internal domestic Interferon person 100% higher than when injected, IFN-EU. Ideal for emergency treatment and prevention Flu and colds, reducing the risk of the probability of the disease in more than 2 times.
The preparation includes vitamins E and C, which enhance its antiviral action 14 times.
Indications
Treatment and prevention Flu and ARI adult patients and in children.
In the complex treatment of patients with chronic and acute hepatitis B , Including chronic hepatitis B Which is complicated glomerulonephritis .
Bronchial asthma, atopic disease, allergic rhinoconjunctivitis the appointment of a specific immunotherapy.
Urogenital chlamydial infection patients adulthood, as part of a treatment.
Contraindications
- period pregnancy ;
- severe allergic diseases ;
- hypersensitivity to the ingredients of the drug-IFN-EU Lipint.
Side effects
When administered orally, the recommended doses of the drug does not cause side effects. However, it should be remembered that the active ingredient of the drug - recombinant interferon when administered parenterally which is flu-like symptoms . In this connection it should be very careful when appointing IFN-EU-Lipinta patients intolerant of drugs containing interferon .
Instructions for use (method and dosage)
Instructions on Reaferon EU Lipint recommends taking the drug by mouth (orally).
Before taking to the internal contents of the vial add boiled or distilled water in the amount of 1-2 ml and shaken vigorously for 1-5 minutes. This should occur complete dissolution of the powder to form a uniform suspension.
In the treatment of acute Hepatitis B adult patients and children of school age take into suspension 30 minutes before a meal twice a day at a dose of 1 million IU. The course of treatment - 10 days.
Patients from 3 to 7 years of taking the drug once a day at a dose of 500,000 ME for 10 days.
After the control of biochemical blood tests possible continuation of the course of therapy until complete disappearance of the clinical symptoms of the disease.
With an inactive and active replicative form chronic hepatitis B At chronic hepatitis B , Complicated glomerulonephritis Take Reaferon EU Lipint 30 mine before meals.
Adult patients and patients on recommended school age 1000000 ME twice a day for 10 days and then transferred to a disposable same dose at bedtime for 30 days.
Patients from 3 to 7 years shows 500,000 IU dose 2 times a day for 10 days and then transferred to a single dose of the same dose at bedtime for 30 days.
When assigning specific immunotherapy drug is taken once a day, preferably in the morning, after 30 minutes of ingestion.
Treatment allergic rhinoconjunctivitis in adults involves the use of a dose of IFN EU Lipint 500,000 ME for 10 days.
Treatment atopic asthma adult patients in a dose passes ME 500000 once daily for 10 days and then transferred to receiving similar doses every other day for 20 days. The total course of therapy for 1 month.
In order to prevent Acute respiratory infections and influenza Reaferon EU Lipint administered 30 minutes before a meal. Patients over 15 years of twice-weekly recommended taking the drug at a dose of 500,000 ME. The course is designed for 30-day use in the growth of the number of respiratory diseases.
Patients from 3 to 15 years prescribe a prophylactic dose of 250,000 ME, shall be made within 7 days - 2 times. The course is designed for 30-day use in the growth of the number of respiratory diseases.
For treatment Acute respiratory infections and influenza patients older than 15 years prescribed dose of 500,000 ME, taken twice a day for 3 days.
Patients from 3 to 15 years old receive a dose of 250,000 ME 2 times a day for 3 days.
Combined therapy urogenital infections in adult patients require the adoption of oral IFN-EU-Lipint at a dose of 500,000 ME, broken into two doses a day for 10 days.
Overdose
Under recommended doses, throughout the course of treatment, overdose is possible.
Cooperation
Interferon alfa It has the ability to reduce the activity P-450 cytochromes , Thereby affecting the metabolism Warfarin, phenytoin, cimetidine, Courant diazepam, theophylline, propranolol, some cytostatics.
IFN-EU-Lipint can exacerbate the neurotoxic, cardiotoxic, myelotoxic effect of drugs taken in the past or in parallel with it.
You should avoid the combination with receiving immunosuppressive drugs and drugs depressing the central nervous system.
Terms of sale
Prescription.
Storage conditions
In the refrigerator at a temperature not exceeding 8 ° C.
Shelf life
12 months.
Analogs
Interferon
Nazoferon
Viferon
Infagel
IFN-EU
IFN-Lipint
Altevir
Algeron
Genferon Light
Genferon
Grippferon
- Genferon;
- Intron A;
- Interlock;
- Inferon;
- Layfferon;
- Lokferon etc.
Babies
At the recommended doses, pediatric patients appointed by 3 years.
With alcohol
Use of alcoholic beverages during treatment with IFN-EU-Lipint not recommended.
During pregnancy and lactation
IFN-EU-Lipint contraindicated during pregnancy .
Reviews for IFN-EU-Lipint
Reviews of the oral formulation of the EU-IFN-Lipint, as a means of prevention ARI and Flu during periods of exacerbations are positive. Its high efficiency is marked as adult patients and parents who have used the drug to maintain the immunity of their children.
Among the reviews for the treatment of other diseases included in the indication for the drug, you can meet single negative reviews related to the side effects that are likely to result from the breach of storage or transport.
Price IFN-EU-Lipint where to buy
The price of IFN-EU-Lipint averages:
- 250,000 IU №5 - 500 rubles;
- 500,000 IU №5 - 750 rubles;
- 500,000 IU №5 - 850 rubles;
- 1000000 IU №5 - 950 rubles.
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