Description overdue on 09/19/2014
- Latin name: Cerazette
- ATC code: G03AC09
- Active substance: Desogestrel (Desogestrel)
- Manufacturer: ORGANON N.V. (Netherlands)
- Composition
- Product form
- Pharmacological action
- Pharmacodynamics and pharmacokinetics
- Indications
- Contraindications
- Side effects
- Instructions for use Charozetty (method and dosage)
- Overdose
- Cooperation
- Terms of sale
- Storage conditions
- Shelf life
- Analogs
- Reviews
- Price, where to buy
Composition
The main ingredient of the drug - The D ezogestrel . Besides Charozetta (Cerazette) contains the following additional components: macrogol 400, colloidal silicon dioxide, anhydrous, lactose monohydrate, povidone, hypromellose, talc, alpha-Tocopherol, corn starch, stearic acid, titanium dioxide.
Product form
The medicine comes in the form of lenticular tablets are coated with a white film-coated engraved with «ORGANON» with five-pointed star on one side and «KV» over the number two - the other.
Pharmacological action
Progestogens and contraceptive drug.
Pharmacodynamics and pharmacokinetics
Charozetta is intended for oral contraception . Action the drug due to inhibition of ovulation and condensation cervical mucus .
The use of this tool reduces the concentration Estradiol to levels that are characteristic of the early the follicular phase .
The drug is rapidly absorbed and converted to the active metabolite etonogestrel . At regular application the maximum plasma concentration is reached later, roughly 100 minutes after the regular pills. The bioavailability of approximately 70%.
The preparation preferentially binds to whey ( albumin . globulin ).
Active ingredient metabolized by means of hydroxylation and dehydrogenation And converted into the active metabolite etonogestrel , Through which are formed sulfate and glucuronide conjugates .
The drug is excreted mainly in the urine and feces as free Steroids and conjugates .
Indications
This tool is used for contraception. Some doctors also prescribe it in endometriosis .
Contraindications
The medicine should not be taken if:
- acute venous thromboembolic violations;
- hypersensitivity to its components;
- malignant tumors are sensitive to sex hormones (diagnosed or suspected);
- pregnancy ;
- severe violations of the liver (even history );
- Vaginal bleeding of unknown aetiologies .
Side effects
Side effects when using Charozetty may include the following: headache , Spotting, mood changes, nausea, acne , Breast pain, weight changes, amenorrhea , Decreased libido.
Less common manifestations such as vaginitis . ovarian cysts . alopecia , Sensation dyscomfort when using contact lenses, dysmenorrhea , Vomiting, fatigue.
In rare cases documented side effects such as rashes, erythema nodosum and hives .
Instructions for use Charozetty (method and dosage)
The medicine should be consumed on a tablet a day, without missing a single reception. It is necessary to to do it at one and the same time in the within 28 of day in the order, written on the packaging. Instructions on Charozettu recommends to wash down pills necessary amount of liquid. To receive the next pack of pills you need to start immediately after the end previous.
Before that hormonal contraceptives have not been applied, the instructions for use Charozetty provides initiation of the first day of the menstrual cycle. Although it is possible to start the course in 2-5 days, but in this case it is recommended during the first week to use additional measures of contraception.
When changing from a combined hormonal contraceptive drugs Charozetty course begins the next day after receiving funds or the previous day removal vaginal rings . transdermal patch . Additional contraception in this case is not necessary.
In the transition from the "mini-pill" Charozettu can be taken any day. If you previously used implant or gestagenvysvobozhdayuschaya intrauterine system , The first tablet drug used on the day of removal. When contraceptive injection form Charozettu to go on a day when I had to do the next shot. After an abortion in the I trimester need to start taking this drug immediately. Additional contraception in this case is not necessary.
After an abortion in the II trimester the beginning of the course of the preparation is possible only after 21-28 days and 6 weeks after birth. If the application Charozetty started later, in the first week of additional measures are necessary for reliable contraception. Moreover, pregnancy should be excluded.
If you missed a pill less than 12 hours, it should be taken immediately, as soon as possible, following reception held at the usual time. If a pill is missed more than 12 hours, you need to take it immediately as soon as possible, but within the next week to use additional methods for reliable contraception.
In disorders of the gastrointestinal tract is also better to use additional methods of contraception.
Overdose
At higher doses may be nausea, slight vaginal bleeding, vomiting. Treatment is symptomatic.
Cooperation
Studies on the interaction of the drug with other drugs have been conducted. However, based on empirical observations it is known that, when combined with hydantoin . Carbamazepine . Oxcarbazepine . Troglitazone . Griseofulvin . barbiturates . Rifampicin . Rifabutin and Felbamate may cause vaginal bleeding and reducing the effectiveness of the contraceptive effect. One of the drugs in this case to cancel. If this is impossible, you must use an additional method of preservation from pregnancy throughout the entire course of treatment one of the the specified means and within a week after its completion. And when receiving Rifamptsina and within 28 days after the last application.
When using of medicines, inducing enzymes liver, is better to refuse from the use of tablets Charozetty and go to the non-hormonal methods protection from unwanted pregnancy.
Reception of of activated of coal may reduce effect of the drug. So when this combination is recommended to use additional contraception.
Terms of sale
This tool is available only by prescription.
Storage conditions
The medicine should be kept out of reach of children, protected from sunlight and dry place. Optimum temperature - 2-30 ° C.
Shelf life
Store this medication should be no longer than 3 years.
Analogs
Laktinet
Postinor
For those looking for analogues Charozetty, experts recommend Laktinet .
Reviews Charozette
Birth control pills Charozetta reviews on forums get a variety. For the most part, however, the opinion positive . Negatively expressed only by those for whom the reception of the funds is not without side effects (mainly weight gain and disruption of the menstrual cycle). Reviews Charozette breastfeeding also generally positive. Only in some rare cases, women celebrated decrease the amount of milk . Reviews physicians also demonstrates the effectiveness of this drug. Very often it is administered after the birth, because it is not contraindicated in Lactation .
Price Charozetty
Price Charozetty in a package of 28 tablets - 800 rubles. The means in a package of 84 pills costs about 2000 rubles. Such price Charozetty to many seems too high, so women all longer are trying to find analogues of the given preparation.
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