Description overdue on 11/16/2014
- Latin name: Tagista
- ATC code: N07CA01
- Active substance: Betahistine (Betahistine)
- Manufacturer: Ltd. "MAKIZ PHARMA", Russia
- Composition
- Product form
- Pharmacological action
- Pharmacodynamics and pharmacokinetics
- Indications Tagisty
- Contraindications
- Side effects
- Tablets Tagista, instructions for use
- Overdose
- Cooperation
- Terms of sale
- Storage conditions
- Shelf life
- Cautions
- Analogs
- Synonyms
- Babies
- During pregnancy (and lactation)
- Reviews
- Price, where to buy
Composition
1 tablet medicament comprises Tagista 8; 16 or 24 mg betahistine dihydrochloride - The active ingredient.
Auxiliary ingredients:
- MCC;
- Kollidon 25;
- potato starch;
- Aerosil;
- citric acid;
- magnesium stearate;
- talc.
Product form
PM comes in the form of tablets of 30, 50, 60 or 90 units in a single package.
Pharmacological action
Improving microcirculation .
Pharmacodynamics and pharmacokinetics
Betahistine Is the active ingredient of the drug Tagista mainly affects histamine receptors H1 and H3 vestibular nuclei of the CNS and the inner ear . By taking direct agonistic effect on H1, and not directly on the NC vascular receptors of the inner ear improves penetration and microcirculation capillaries Thereby normalizing in labyrinth and the cochlea Pressure endolymph . Also, betahistine It affects the increased blood flow in the basilar artery and oppression through the NT receptors in the nuclei of the vestibular nerve exhibits a pronounced central action. Normalises neuronal conduction of the vestibular nuclei in the brainstem level area of the brain.
When receiving the drug reduced the intensity and frequency dizziness Reduced sensation tinnitus . improves hearing (when the preceding lowered).
When an internal reception betahistine rapidly absorbed and has a tenuous connection with plasma proteins . After 3 hours, it reached the maximum plasma concentration.
T1 / 2 about 3 - 4 hours.
As metabolites almost completely excreted in the urine within 24 hours.
Indications Tagisty
Indications Tagisty include the following disease states:
- Meniere's disease or syndrome;
- vestibular vertigo , Evolved for various reasons (for the prevention and treatment);
- syndromes which are accompanied headaches and / or dizziness . down hearing . noise in the ears, nausea and vomiting .
Contraindications
At this time, the only absolute contraindication to receive a Tagisty hypersensitivity the components of the tablet, including the active substance and auxiliaries.
Also, there is no reliable data on the effectiveness of Tagisty and its spillover effects on the body of the patient during Lactation and pregnancy And under 18 years old, from which the drug is not administered tablets in these periods.
The drug with caution and under constant supervision when taking peptic ulcer (including guidance history ) asthma . pheochromocytoma .
Side effects
Among the side effects of the drug most commonly observed: gastrointestinal disorders . headache and allergic reactions as hives . Skin itching and / or rash . Also, there is evidence of the development angioedema .
Tablets Tagista, instructions for use
Instructions for use Tagisty recommends taking the medication orally with meals.
Tablets with a mass content betagistina - 8 mg administered three times daily 1-2 tablets, 16 mg - three times daily and 1 / 2-1 tablet of 24 mg twice a day for one tablet.
Generally, improving the disease state is observed at the beginning of treatment. Persistent therapeutic effect is the end of the second week of therapy and may develop over the next few months. The duration of Tagisty determined individually, but most often the course of therapy takes a long time.
Overdose
If overdose occurs Tagisty nausea followed by vomiting Possible convulsions .
It shows the standard symptomatic treatment, including gastric lavage with a further reception Activated Carbon .
Cooperation
No information on the cases of incompatibility or interactions with other drugs.
Terms of sale
Tagista released on presentation of a prescription.
Storage conditions
In a place protected from children and light at a temperature not exceeding 25 ° C.
Shelf life
36 months.
Cautions
Betahistine shows no Sedation In this connection, it can be assigned to the driver or other people whose profession requires quickness of psychomotor reactions.
Analogs Tagisty
Vestibo
Cinnarizine
Stugeron
Betaserk
Analogs of the drug presented Tagista drugs Stugeron and Cinnarizine .
Synonyms
Betaver . Betaserk . Betahistine . Vestibo . Micrograins . Vestikap etc.
Babies
Not applicable for the treatment of patients under 18 years.
During pregnancy (and lactation)
Do not set the period Lactation and pregnancy .
Reviews Tagiste
Among the physicians who use the drug, reviews about Tagiste suggests diversifying effect of the drug on various pathogenetic factors of vertigo That is the reason for his appointment in many disorders vestibular .
Efficiency Tagisty, with minimal side effects, is estimated at 95% of the cases, the drug can be recommended a wide range of patients.
Reviews of people, for whatever reason, took Tagistu, varied from very positive to negative. In fairness it should be noted that it is often possible to find evidence of self-prescribing betahistine and negative effects of their admission for dizziness. This may be related to the cause of dizziness, incorrect dosage, short-course therapy, and many other factors, so that before any treatment should undergo medical advice.
Price Tagisty where to buy
The cost of the drug depends on the number of tablets in the original packaging and mass content of the active ingredient, such as the average price Tagisty 24mg №30 - 130 rubles; 16 mg №30 - 100 rubles; 8 mg №30 - 80 rubles.
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