Description overdue on 10/24/2014
- Latin name: Nazoferon
- ATC code: L03AB05
- Active substance: Interferon alfa-2b (Interferon alfa-2b)
- Manufacturer: PJSC "Farmak", Ukraine
- Composition
- Product form
- Pharmacological action
- Pharmacodynamics and pharmacokinetics
- Indications
- During pregnancy (and lactation)
- Contraindications
- Side effects
- Instructions on Nazoferon (method and dosage)
- Overdose
- Cooperation
- Terms of sale
- Storage conditions
- Shelf life
- Analogs
- With alcohol
- Reviews
- Price, where to buy
Composition
Nazoferon drops and sprays contain the active ingredient: interferon alfa-2b.
Accessories: trometamol hydrochloride, lysine hydrochloride, methyl parahydroxybenzoate, trometamol, hypromellose, disodium editat, potassium chloride, water for injections.
Product form
Available in the form of the drug spray and nasal drops , Placed in glass vials of 5 ml.
Pharmacological action
Nazoferon has antimicrobial, antiviral, immunomodulatory and anti-inflammatory action.
Pharmacodynamics and pharmacokinetics
Basis Nazoferona presented material - recombinant human interferon alfa-2b . For this component is characterized by inhibition of viral replication - influenza, adenoviruses and so on, by inhibiting the process of transcription and translation. Wherein interferon It exhibits an antiproliferative action due to inhibition of cell proliferation, which are infected with viruses, especially RNA and DNA containing viruses.
Also noted the ability of interferon in the initiation of protein synthesis - specific enzyme Which prevents translation through phosphorylation of its initiation factor. In addition, human interferon activates specific ribonuclease , Have a damaging effect on the messenger RNA viral cells. Additionally, stimulates production of other cytokines induced by specific enzymes, inhibited cell proliferation, manifested immunomodulatory effects by increasing phagocytic activity and cytotoxic effects of lymphocytes directed to the target cell. Interferon alfa-2b characterized by severe tissue specificity and the attitude to the mediators of immunity. This material provides reliable protection of the human body from a variety of viruses, bacteria, pathogenic fungi, mycoplasmas and other infectious agents.
Indications
The drug is indicated for the treatment of Nazoferon:
- SARS;
- influenza;
- colds Accompanied by frequent and prolonged illness in the upper respiratory tract.
Furthermore, the tool is recommended to the purpose of treatment and prevention for pregnant women, for babies in the first days of birth, particularly if they are forced to be in contact with people with flu or SARS. Also, as a prophylactic drug used in hypothermia, while the seasonal incidence, during epidemics in children or adults collectives.
Nazoferon during pregnancy
The drug is recommended to apply in the period Feeding your baby And when pregnancy In order to prevent disease in the early stages when the disease is the mother's body can cause malformations in the fetus.
Contraindications
Do not prescribe the drug for:
- increased Sensitivity to its components;
- severe forms allergic disorders history.
Side effects
Generally, treatment Nazoferonom not cause any side effects.
However, we should not exclude the occurrence of Allergies Caused by high sensitivity or intolerance to human Interferon and other components of the formulation.
Instructions on Nazoferon (method and dosage)
Nazoferon intended for insertion into each nasal passage, according to the established dosage regimen. That means better distributed in the nasal cavity should be gently massaged after putting his fingers a few minutes nostrils. In pediatrics actively used Nazofen for children, produced in the form of drops. Instructions for children allows the use of this tool, even for the treatment of newborn babies.
Thus, the children used to the drug Nazoferon guide recommends that when the first symptoms SARS or Flu . It is desirable to perform it for the first 5 days. This drops prescribed for children newborn babies and kiddies to the year 1 drop daily. Children 1-3 years - 3-4 times daily 2 drops.
Nazoferon spray is recommended for a more adult patients, both for prevention and for treatment. On average, the rate may be 6-7 days. If necessary, repeat the preventive courses. A single contact with SARS patients allows only one injection or instillation of the drug. During the seasonal increase morbidity set a single application in the morning, according to age dosing at intervals of 1-2 days.
Overdose
Nazoferonom overdoses in clinical practice were observed.
Cooperation
During treatment Nazoferonom uncomplicated colds and SARS no additional symptomatic therapy, for example, reception antipyretic drugs, vasoconstrictors, sulfonamides and so on. In addition, for the treatment of fever may be appointed anti-inflammatory drugs.
Simultaneous use and Nazoferona nasal vasoconstrictor promotes drying of the mucous membranes of the nasal cavity.
Terms of sale
The preparation is available in pharmacies without a prescription.
Storage conditions
For storage of the drug targets a dark, cool place, away from children.
Shelf life
2 years. After opening the bottle if stored temperature storage conditions - the temperature of 2-8 C, the drug retains suitability within 10 days.
Analogs
Interferon
Viferon
Infagel
IFN-EU-Lipint
IFN-EU
IFN-Lipint
Altevir
Algeron
Genferon Light
Genferon
Grippferon
The main analogue of the drug presented Interferon alfa-2b.
Also, have a similar effect: Arbidol, Amiksin, Viferon and others.
Alcohol
Direct contraindications to the simultaneous use of drugs and alcohol is not, but preparations containing interferon , Drinking alcohol is not recommended.
Reviews Nazoferone
It is known that this drug can be used practically for children from birth. Therefore, reviews of it are found in large quantities in various forums on the topic of children and mothers. However, many parents give fairly good efficiency score Nazoferona.
The result of the treatment of young children getting quick relief from mucous secretions from the nose, eliminating swelling and so on. Furthermore, this children's product is excellent prophylactic that protects against infections and colds. You can also find reviews of Nazoferone at pregnancy Which only confirm its effectiveness.
Preparations Interferon are essential and highly effective means of prevention and treatment of infections and colds. However, to use them without a prescription is not recommended. In any event, in addition to immediate use of such funds, it is important to try to strengthen the natural immune defenses, then man would only need minimal support.
Price Nazoferona where to buy
Price Nazoferona children in drugstores Moscow is 374-390 rubles. The cost of the drug as a spray - 400-420 rubles.
Children Nazoferon pharmacies in Kiev can be purchased for 57, 38 UAH., Spray - for 67, 16 UAH.
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