Description overdue on 09/29/2014
- Latin name: Helarium Hypericum
- ATC code: N06AX
- Active substance: Extract of Hypericum perforatum herb (Hyperici perforati herbae extract)
- Manufacturer: Bionorica SE., Germany.
- Composition
- Product form
- Pharmacological action
- Pharmacodynamics and pharmacokinetics
- Indications for use of the drug
- Contraindications
- Side effects
- Instructions on gelarium Hypericum (method and dosage)
- Overdose
- Cooperation
- Cautions
- Terms of sale
- Storage conditions
- Shelf life
- Analogs
- With alcohol
- Reviews
- Price, where to buy
Composition
The tablet contains the active ingredient: St. John's wort extract standardized and additional components.
Product form
Available in the form of Hypericum gelarium tablets Coated, 15 pieces in blisters, for 2 or 4 packs per bundle.
Pharmacological action
Hypericum has gelarium anxiolytic and antidepressant action.
Pharmacodynamics and pharmacokinetics
The active ingredient of the drug, Hypericum , Prevent the development of disorders of neurotransmitter transmission, it modulates the secretion of IL-6 and inhibit catechol-O-methyltransferase and monoamine oxidase. This eliminates the symptoms of emotional lability, oppressed mood, anxiety and stress.
Data on the pharmacokinetics gelarium Hypericum not.
Indications for use of the drug
The drug is prescribed for:
- psycho-vegetative disorders , eg, lowering of mood, apathy ;
- neurotic reactions ;
- depressive states mild to moderate severity.
Contraindications
Do not take Hypericum gelarium at:
- individual high Sensitivity to him;
- childhood less than 12 years ;
- lactase deficiency, lactose intolerance and fructose, glucose-galactose malabsorption, or sucrase isomaltase deficiency;
- Available photosensitivity the skin to UV radiation;
- simultaneous application with cyclosporine, tacrolimus, indinavir, amprenavir and other HIV protease inhibitors, for example, in the treatment of HIV-positive patients, and warfarin, irinotecan and MAO inhibitors. In such cases it is necessary to observe the interval is not less than 14 days;
- lactation, pregnancy .
Side effects
In the treatment of Hypericum may develop gelarium Allergic reactions and : rashes, itchy skin, eczema, skin pigmentation Sensitivity to ultraviolet rays and so on.
It is also possible disorders of the nervous system in the form of: worry And strong fatigue and headaches .
Often suffering digestive system, which is manifested nausea . abdominal pain . dryness mucosa oral . flatulence, diarrhea or constipation, anorexia .
In addition, it can manifest violation of the blood, for example, Iron-deficiency anemia .
Instructions on gelarium Hypericum (method and dosage)
Tablets for oral Reception in whole. According to the instructions for use gelarium Hypericum, to obtain the maximum therapeutic effect and reduce the risk of side effects, the drug should be taken along with food .
The duration of treatment and allowable dosage of the drug determined by the attending physician taking into account the nature of the disease and the individual patient. For adults and teenagers usually set the standard dose one tablet three times a day . As a general rule, the therapeutic course should not be less than 4 weeks. When a period of one month from the beginning of treatment, patients do not notice improvement, it requires refinement of diagnosis and correction of the treatment regimen.
Overdose
In cases of overdose in patients have dose-dependent increase in symptoms.
This symptomatic therapy. Also recommended 1-2 weeks to be protected from direct sunlight.
Cooperation
Simultaneous treatment with hypericum gelarium indirect anticoagulants - phenprocoumon, warfarin, imatinib and other cytotoxic drugs, midazolam, digoxin, amitriptyline, fexofenadine, benzodiazepines, nortriptyline, theophylline, methadone, verapamil, simvastatin and finasteride It can greatly reduce their effectiveness.
Combination therapy with antidepressants , eg: nefazodone, paroxetine, sertraline, buspirone, triptans often leads to the strengthening of their actions, as well as the development of undesirable symptoms: nausea, vomiting, fear, anxiety, confusion .
Sometimes, when a joint reception gelarium Hypericum increases the photosensitizing effect of a number of drugs: tetracyclines, thiazide diuretics, sulfonamides, quinolones and piroxicam .
Also, the drug can prolong the dream that causes agent for general anesthesia or narcotic analgesics, but shortens sleep caused by barbiturates. The decrease in the hypotensive effect reserpine and a decrease in the concentration of cyclosporine and indinavir in the blood.
Concomitant use with desogestrel and ethinylestradiol increases the risk of bleeding and the rate of metabolism. Reduced concentration Digoxin in the blood and its efficiency.
If during treatment received oral contraceptives , The patients need to take care of other contraceptive methods.
Cautions
Gelarium Hypericum can be administered to patients with diabetes Because in a single tablet contains less than 0, 03 accounted for XE.
During treatment it is necessary to abandon the solarium and avoid exposure to sunlight.
Effects on ability to drive vehicles and activities requiring attention and quick reactions has not been established.
Terms of sale
The drug is sold without a prescription.
Storage conditions
For storage of the drug requires a cool, dry place, protected from sunlight and children.
Shelf life
3 years.
Analogs
Despres
Negrustin
Trittiko
Agomelatine
Azafen
Neyroplant
Main counterparts gelarium Hypericum - a drug: Despres, Tsipraleks, Reksetin and Fluoxetine .
Alcohol
It is not recommended to combine the reception of the drug with alcohol. This combination can cause considerable psychophysical disorders in humans.
Reviews gelarium Hypericum
As the reviews of gelarium, it receives patients who are concerned about a variety of disorders associated with the activity of the nervous system. Many users report that prior to the appointment of the drug he prescribed and other drugs. However, really helps to eliminate unpleasant symptoms exactly reception gelarium hypericum.
The drug is commonly prescribed to patients with nervous breakdowns . panic attacks . anxiety, fear and heart palpitations . Also, it is actively used as a maintenance therapy in patients with vascular dystonia . Most people celebrate a long and lasting effect.
As for professionals, they believe - for those patients receiving a drug will not be enough. Therefore, reviews of physicians often provide additional guidance on the psychological work on oneself in the form of consulting a psychologist, have lots of fun with loved ones, meditation, listening to soothing music and maintaining a harmonious mood. Only such an approach promotes physical and mental state of the person.
Price gelarium Hypericum where to buy
It should be noted that the price gelarium Hypericum in various cities of Russia differs slightly in the regions it ranges from 144 rubles.
Gelarium Hypericum can be bought in Moscow for 200-250 rubles.
Buy in St. Petersburg medicine can cost from 180 rubles.
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