Effezel

Description overdue on 11/20/2014

• Latin name: Effezel
• ATC code: D10AD53
• Active substance: Adapalene and benzoyl peroxide (Adapalene + Benzoyl peroxide)
• Manufacturer: GALDERMA (Switzerland)

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• Composition
• Product form
• Pharmacological action
• Pharmacodynamics and pharmacokinetics
• Indications
• Contraindications
• Side effects
• Instructions on Effezel (method and dosage)
• Overdose
• Cooperation
• Terms of sale
• Storage conditions
• Shelf life
• Cautions
• Analogs
• During pregnancy (and lactation)
• Reviews
• Price, where to buy

Composition

1 g of gel contains 1 mg adapalene 25 mg benzoyl peroxide   and auxiliary components: poloxamer, glycerol, polysorbate, isohexadecane, simulgel, water, sodium docusate, sorbitan oleate, edetate disodium.

Product form

Effezel issued in the form of an opaque gel   with a slightly yellow tinge in laminated plastic tubes. Capacity 2, 15, 30, 45, 60, '90 Each tube is packed in a stack of cardboard.

Pharmacological action

Medicines to treat blackheads . The components of the drug potentiate the effect of each other.

Adapalene   - A stable derivative of naphthoic acid and retinoid effect. The active ingredient has a strong inflammatory action processes and modulates cell differentiation and keratinization. The principle is based on the effects of combining adapalene and specific nuclear receptors of retinoic acid. Modern medicine requires that the local impact adapalene able to normalize the differentiation of follicular epithelial cell, which leads to reduced formation of microcomedo. In vitro substance inhibits the process metabolism   arachidonic acid and of inflammatory mediators. Thus, adapalene is able to reduce the severity of the inflammatory component of acne.

Benzoyl peroxide   has antimicrobial effect and directly affects the sebaceous hair follicle with acne. The component has a keratolytic, sebostaticheskoe and exfoliating effects. Benzoyl restrict sebum production, which plays an active role in the formation of acne.

Pharmacodynamics and pharmacokinetics

Adapalene has no systemic impact. Benzoyl poorly penetrates the skin and quickly transformed to benzoic acid .

Indications

Gel Effezel prescribed for acne, followed by pustules . comedones   and papules .

Contraindications

Children under 12 years of safe medication has not been investigated. The drug is not prescribed for allergic responses   and individual hypersensitivity .

Side effects

• contact dermatitis;
• dry skin;
• atopic dermatitis;
• sunburn;
• itching;
• burning.

The above negative symptoms disappear on their own in 7 days.

Instructions on Effezel (method and dosage)

Ointment is recommended to apply before going to bed on dry skin with a thin layer of clean, avoiding contact with the mucous membrane of the lips and eyes. A remarkable therapeutic effects recorded after 1-4 weeks of regular use. In the absence of effect and development of the strong negative reactions it is recommended to cancel the self-Gel Effezel. Instructions for use contains a reference to the possibility of applying additional moisturizing agents that do not have a comedogenic effects.

Overdose

If swallowed, held posindromnaya therapy.

Cooperation

Application dries, peels and irritants recommended limit for the entire period of treatment. It is unacceptable simultaneous treatment with other retinoids. Adapalene incapable absorbed into the systemic circulation and enter into contact with other drugs.

Terms of sale

Released upon presentation of a medical prescription form.

Storage conditions

Restrict the admission of young children. Temperature range - up to 30 degrees.

Shelf life

The exposed tube can be stored no more than six months. Shelf life of sealed tubes - 2 years.

Cautions

Application is inadmissible on the eczematous skin changes. Avoid prolonged contact with the mucous membranes, nostrils, mouth and eyes. Do not apply the medication in the presence of abrasions and cuts in the skin. The gel contains in its composition propylene glycol , Which itself is able to exert an irritating effect. With the development of allergic response, medication overturned.

It is recommended to limit exposure UV   and sunlight   on the skin. The gel may discolor dyed fabrics and hair, it is important to consider when using the drug.

Analogs

Match code ATC 4th level:

• Klenzit
• Retinoic ointment
• Retin A
• Radevit
• Videstim

Analogs Effezel gel with the same effect:

• Metrogil gel;
• Aknestop;
• Bezugrey;
• Arbum;
• Klenzit.

During pregnancy and lactation

Reliable information about the safety of adapalene and benzoyl peroxide in women with pregnancy   no. Registered toxic effects of adapalene and benzoyl on the reproductive system when fed to animals orally to the above components.

If pregnancy occurs during therapy Effezelom recommended the abolition of the independent gel. The drug can be applied at breast-feeding While avoiding direct contact of the drug and the newborn baby.

Reviews on Effezel

Reviews Effezel gel encountered on the internet, mostly positive. Participants thematic forums reported that the drug is widely used acne. Reviews on Effezel indicate a high efficiency of a medicament for the treatment of acne and acne in people of different age groups. Rarely appear negative reactions in the form of irritation and flaking.

Price Effezela where to buy

Price Effezela gel 30 g in Russia - 950 rubles. Buy medicine in Ukraine is possible for 460 USD.

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