Description overdue on 03/29/2014
- Latin name: Tabex
- ATC code: N07BA
- Active substance: Cytisine (Cytisine)
- Manufacturer: "Sopharma" JSC, Bulgaria
- Composition
- Product form
- Pharmacological action
- Pharmacodynamics and pharmacokinetics
- Indications
- Contraindications
- Side effects
- Instructions for use Tabex (method and dosage)
- Overdose
- Cooperation
- Terms of sale
- Storage conditions
- Shelf life
- Cautions
- Analogs
- Babies
- With alcohol
- During pregnancy (and lactation)
- Reviews
- Price, where to buy
Composition
The composition of one tablet is as follows: cytisine (active substance) 1, 5 mg. Also includes additional excipients: microcrystalline cellulose . lactose monohydrate . magnesium stearate . talc .
The drug film coating comprising Opadry II brown . Titanium dioxide . polyvinyl alcohol partially hydrolyzed, macrogol 3350 . talc . iron oxide .
Product form
The drug comes in the form of lenticular, round tablets that are covered with a light brown film-coated.
The drug is available in blisters that holds 20 tablets. The stack of cardboard there are 5 such packages and annotation.
Pharmacological action
The drug is H-holinomimetikami . It has a stimulating effect on the nicotinic receptors of autonomic ganglia has reflexively stimulating effect on the respiratory center, promotes the release of chromaffin cells of the adrenal medulyarnoy adrenaline Increases arterial pressure .
As a consequence, Tabex effectively reduces the dependence of the organism Nicotine . Under the influence of the drug the taste of smoking becomes unpleasant to humans. Gradually the desire to smoking decreases. The drug reduces abstinence syndrome That is associated with nicotine withdrawal.
In general effects on the body cytisine close to the mechanism of the influence of nicotine. This allows you to gradually stop smoking and significantly reduce the intensity of abstinence phenomena.
Pharmacodynamics and pharmacokinetics
A study of the pharmacokinetics of Tabex in humans have been conducted. Wikipedia indicates that data on the pharmacokinetics of the drug were the result of research on animals. The substance is absorbed from the gastrointestinal Tsitizin quickly, not completely. In mice after oral application of the drug observed degree of resorption 42% in rabbits - 34%. For oral use the highest concentration of the drug in mice was reached after 2 hours, the rabbits - after 35 minutes. Maximum plasma concentration of cytisine in the notes kidney . liver . adrenals .
Half-life of the drug, received intravenously in mice is 200 minutes, 18% of the dose means taken orally in mice excreted within 24 hours. In rabbits, the half-life after intravenous application is 37 minutes.
Tabex is composed of cytisine Whose impact on the body similar to the effects of nicotine.
Indications
The drug is taken with severe nicotine dependence In order to facilitate the state for smoking cessation.
Contraindications to Tabeks
Do not take the drug to those who have observed hypersensitivity to cytisine or to other components of the drug. Contraindications to Tabeks have been reported in people who suffer some physical and mental diseases. In particular, the contraindications to the pill smoking observed in such diseases:
- acute form myocardial infarction ;
- Arrhythmia ;
- angina ;
- circulatory disorders in the brain;
- bleeding from large vessels;
- atherosclerosis ;
- arterial hypertension;
- exacerbation duodenal and gastric ;
- pulmonary edema;
- bronchial asthma .
Doctors prescribed with caution Tabeks and its analogues to patients schizophrenia . coronary heart disease . diabetes , Chromaffin adrenal tumors . gastroesophageal disease . hyperthyroidism And patients kidney and hepatic insufficiency .
Children and people who have turned 65 years old, it means appointed only after an assessment of how to relate the benefits and potential risks.
Side effects Tabex
Side effects may occur tablets from a number of body systems. Reviews of the side effects of the drug indicate that the drug may have the following side effects:
- feeling dry mouth . diarrhea . constipation . nausea , Taste change and fluctuations in appetite - from the digestive system;
- dizziness and headache . drowsiness or insomnia , Periodic increase irritability - the part of the nervous system;
- tachycardia , Increased blood pressure, breathlessness , Pain in the chest - from the circulatory system.
In addition, there may be weight loss . myalgia . high perspiration , Allergic reactions.
Usually, the side effects disappear on their own. If side effects are compounded Tabex, be sure to consult with a specialist.
Instructions for use Tabex (method and dosage)
Instructions on Tabeks involves some method of using tablets. Originally assigned to 1 tablet per day five times, after the dose should be reduced to 1-2 tablets per day. Treatment with this drug lasts from 20 to 25 days. Dosing Tabex must necessarily endorse the doctor in each individual case. How to take Tabeks, it is advisable to learn more from a specialist who prescribes treatment. If the patient continues to take the pills correctly, but there is no effect, you need 2-3 months to undergo treatment again.
Advise patients how to take pills, and doctors warn that smoking is necessary to cease no later than five days after the start of treatment.
Overdose
With an overdose of a person may experience the following symptoms
- nausea and vomiting ;
- convulsions ;
- general feeling of weakness ;
- tachycardia . increased heart rate ;
- respiratory paralysis .
If such symptoms appear, it is required to completely stop drug treatment.
Patients who are trying to quit using the drug, the dose and exceeded its reception, you need to wash out the stomach, if needed - to enter infusion solutions . drugs against seizures and other means relieving symptoms. It is important to closely monitor the level of heart rate and blood pressure.
Cooperation
Tabeks not received simultaneously with drugs for the treatment of TB Since it may intensify their side effects. On physical and chemical incompatibilities of the drug is not known.
Terms of sale
In pharmacies dispensed by prescription.
Storage conditions
The drug belongs to the list B. It should be stored in a place protected from light and moisture, storage temperature should not exceed 25 ° C. Protect tool from children, store in the original packaging.
Shelf life
Shelf life Tabeks - 2 years.
Cautions
It means appropriate to take only those who knowingly intend to give up smoking.
On the ability to drive vehicles and work with complex mechanisms the drug has no effect.
Analogs
CHAMPIX
Nicorette
Analogs of the drug - this means that the active substance is cytisine. Such means are produced in the form of tablets ( tsititon . cytisine . Lobesil ), In the form of special films that are glued to the skin ( tsiperkuten ).
What better Brizantin or Tabeks?
There are a number of drugs that have an impact on the smoker, like Tabeks. It Brizantin . Nicorette . CHAMPIX and others. At the heart of the drug contained Brizantin antibodies a brain-specific proteins, thereby reducing the human inclination to nicotine. However, that better Brizantin Tabeks or can be determined only after an individual consultation with a doctor. The cost of the drug in Moscow is 280 rubles.
Nicorette or Tabeks - which is better?
The preparation Nicorette It contains nicotine, so it is used as replacement therapy during weaning from tobacco smoking. Nicorette is released in the form of chewing gum, nicotine is released and thus absorbed in the body gradually. The cost of the drug in the form of chewing gum in Ukraine is from 75 to 88 USD.
What better varenicline or Tabeks?
As part of varenicline there Varenicline , Interacts with nicotinic acetylcholine receptors. As a consequence of the severity of withdrawal symptoms decreased. There are different opinions about what helps you to quit smoking this drug. But its cost is higher than Tabeks: it is in Ukraine from 335 to 336 UAH. The fact help you quit smoking pill, can learn from the comments of those who have completed a course of such treatment.
Babies
Children who are under 18 years old, Tabeks appointed only after determining how to relate the benefits of this treatment and the existing risk.
With alcohol
The drug can not be combined with intake of alcoholic beverages. Discussing compatibility with alcohol, it should be noted that alcohol affects on human self. As a result, alcohol can stimulate an overdose of nicotine. In addition, while taking alcohol and Tabeks people may feel that such abuse leads to an appreciable loss of taste. Furthermore, side effects are possible:
- shortness of breath and heart palpitations;
- heartburn ;
- high blood pressure;
- increase the urge to smoke.
Therefore, during the process of treatment should refrain from alcohol.
During pregnancy and lactation
Not recommended drug treatment during pregnancy because of the risk embryotoxic effects . Nor is assigned to women during Tabeks Lactation .
Reviews Tabeks
Most of those who are undergoing treatment with this agent, expressed positive feedback about Tabeks. However, those who leave feedback on tablets Tabeks note that this drug should be taken strictly according to the scheme described in the summary of the drug. Negative feedback on the forum left those who noted the existence of side effects in the form of irritability, and others. Also, it is not necessary to practice the treatment of these pills to those who have contraindications to their reception.
Most ex-smokers say that with the help of the drug they were able to efficiently and relatively easy to get rid of this addiction.
Price Tabeks where to buy
The average price for Tabeks in Moscow for a package of 100 pieces of 540 rubles.
Price in Ukraine for a package of 100 pieces is an average of 160 UAH.
How many pills are in a particular city, you can find out by visiting the websites of popular network pharmacies. The cost can vary. Price in Kharkov delivered an average of 180 UAH., Without delivery - 150 UAH. Similar offers can be found in pharmacies in Odessa, Dnipropetrovsk - Here the tablets are offered at prices ranging from 150 to 170 UAH
Price Tabeks tablets from smoking compared with other anti-smoking is quite acceptable. Reviews tablets smoking Tabeks show that one treatment is enough to get rid of this bad habit. On what specific outcome in the process of selecting an effective tool, more detail will tell the specialist.
Where to buy Tabeks depends on residence rights. Buy in Moscow and St. Petersburg medication at any pharmacy. In Krasnoyarsk Tabeks realized in many pharmacy chains, it can also be purchased at online pharmacies. Similarly, the drug sold in Ukraine.
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