Analgene

Description overdue on 12.09.2011

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International name of the drug - Metamizole It refers to a group of non-narcotic analgesics . Product: capsules, solution for i / m, / in the introduction, rectal suppositories, tablets. Analgene   - A non-steroidal anti-inflammatory drug, is derived pyrazolone . Analgin prevents the passage of pain impulses, improves heat transfer and increases the excitability threshold of pain sensitivity in centers hypothalamus . Anti-inflammatory effect is weak. The drug has antipyretic, analgesic and antispasmodic effects.

Indications:

Pain syndrome, intestinal, biliary, renal colic, burns, injuries, shingles, decompression sickness, sciatica, orchitis, headache, myositis . algomenorrhea , Postoperative pain, etc. Feverish syndrome: post-transfusion complications, infectious and inflammatory diseases.

Contraindications:

Liver failure, oppression blood (infectious, cytotoxic   neutropenia . agranulocytosis ), Kidney failure, leukopenia, "Aspirin" asthma , Hypersensitivity. Precautions: in renal disease, long-term alcohol abuse in the circulatory instability. Analgin is contraindicated in pregnancy.

Side effects:

Hypersensitivity, allergic reactions. Urinary system: proteinuria . anuria . interstitial nephritis . oliguria . Bodies of blood: the decline in the number of blood cells.

Overdose:

Vomiting, nausea, oliguria, gastralgia, hypothermia, reduced blood pressure, tinnitus, shortness of breath, paralysis   respiratory muscles, impaired consciousness, hemorrhagic syndrome, convulsions, acute renal failure, tachycardia. Treatment is aimed at gastric lavage, hemodialysis . When seizures recommended intravenous fast barbiturates , Diazepam.

Mode of application:

Analgin in tablet form prescribed 2-3 p. to 250-500 mg per day. One-time no more than 1 g, per day no more than 3g. Single dose for children aged 2-3, the - 50-100 mg. Children 4-5 years - 100-200 mg. Children 6-7 years - 200 mg. Children 8-14 years - 250 mg. Multiplicity of reception 2-3 times a day. Calculation of the dose for children is carried out according to the scheme: 5-10 mg per 1 kg 2-3 times per day. Analgin children under one year is entered only intramuscularly. The preparation at a dose higher than 1 g administered intravenously (to prevent a sharp drop in blood pressure is introduced slowly). Solution for in / and the / m: 3 in day 250-500 mg. One-time no more than 1 g, 3 g per day. Rectal use: Adults 300, 650, 1000 mg. For children candles produced 200 mg.

Special instructions:

Analgin children under 5 years old, receiving cytotoxic drugs prescribed only by a doctor. Reception at analginum hay fever   and bronchial asthma can lead to the development of allergic reactions. With long-term use of the drug to maintain control of the state of peripheral blood. Intramuscular injections are made using a long needle.

Connectivity:

You can not mix analginum and other drugs in the same syringe (development Pharmaceutical incompatibility ). The drug enhances the effect of ethanol . Simultaneous administration of phenothiazine derivatives and dipyrone can cause pronounced hyperthermia . The drug reduces the concentration cyclosporin   in blood. Barbiturates, phenylbutazone and other gepatoinduktory reduce the effectiveness of metamizol. Anxiolytic and sedative drugs increase the analgesic effect of metamizol. Myelotoxic drugs increase the risk of haematological complications.