Description overdue on 08/18/2014
- Latin name: Dimia
- ATC code: G03AA12
- Active substance: Ethinyl estradiol (Ethinylestradiol) + Drospirenone (Drospirenone)
- Manufacturer: Gedeon Richter (Hungary)
- Composition
- Product form
- Pharmacological action
- Pharmacodynamics and pharmacokinetics
- Indications
- Contraindications
- Side effects
- Tablets Dimia, instructions for use (method and dosage)
- Overdose
- Cooperation
- Terms of sale
- Storage conditions
- Shelf life
- Cautions
- Analogs
- During pregnancy (and lactation)
- Reviews
- Price, where to buy
Composition
Dimia - a drug, which is composed of two types of tablets. As part of the same birth control pills Coated white contains ethinylestradiol (0, 02 mg.) And Drospirenone (3 mg.).
In addition, as auxiliary compounds in the drug substance present, such as: corn starch (16, 6 mg.), Including pregelatinized (9, 6 mg.) magnesium stearate (0, 8 mg.) And polyvinyl alcohol copolymer (1, 45 mg.).
Sheath medicament contains complex compounds Opadry II 85G18490 Which, in turn, includes such substances as talc, polyvinyl alcohol, titanium dioxide, and soya lecithin and macrogol.
The second composition tablet (the so-called placebo ), Coated green 37 contains 26 mg. lactose , 42, 39 mg. MSC 0, 9 mg. magnesium stearate 0, 45 mg. colloidal silica And 9 mg. pregelatinized corn starch .
Film cover placebo tablets It contains a set of compounds under the name Opadry II 85F21389 In the chemical composition of which includes macrogol . polyvinyl alcohol . talc, quinoline yellow dye . indigo carmine And dye "sunset."
Product form
Dimia tablets containing active substances Drospirenone and etinilestradion They have a rounded lenticular shape. On one side of the tablet of the drug by stamping marking «G73».
The same circular and lenticular shape placebo tablets different green shell. Each pack contains 28 tablets of the drug that can be packaged in blister 1 or 3.
Pharmacological action
Dimia - a combined preparation, which is single phase contraceptive .
Pharmacodynamics and pharmacokinetics
The medicament contains in its composition ethinylestradiol , and Drospirenone (substance close to progesterone naturally occurring). Active substances that are part of this means of contraception do not have anti-glucocorticoid, estrogen, glucocorticoid abilities And pronounced moderate antimineralokortikoidnym and antiandrogenic action .
His efficiency contraceptive Dimia achieves due to several factors, for example, by inhibition of ovulation Changes endometrium and increased the viscosity of secretions Present in cervix .
When taken orally Drospirenone almost completely and quickly absorbed in the stomach. Maximum concentration in blood (Cmax) is reached after a maximum of two hours after ingestion contraceptive . After step distribution and metabolism Drospirenone excreted kidney , A small portion of the drug goes using bowel .
Active ingredient ethinyl estradiol, which is part of contraceptive, as well as Drospirenone rapidly absorbed and reaches its maximum concentration in the blood through two hours. A compound derived from the body intestines and kidneys .
Indications
Dimia used as a contraceptive.
Contraindications
This contraceptive is contraindicated in conditions such as:
- hypersensitivity to any one of active ingredients of the drug;
- venous or arterial thrombosis ;
- thrombophlebitis ;
- thromboembolism ;
- heart attack ;
- cerebrovascular disorders ;
- angina ;
- some diseases Cardiovascular For example, lesions heart valve or Atrial Fibrillation ;
- stroke ;
- vascular disease of the brain ;
- hypertension ;
- smoking, provided that the woman has reached the age of 35 years or more;
- pregnancy , Including suspected it;
- pancreatitis ;
- period Lactation ;
- renal failure ;
- tumor , Including benign;
- migraine ;
- causeless vaginal bleeding ;
- lactase deficiency ;
- failure Lappa .
Caution should be used when contraceptives Dimia obesity, angioedema, otoroskleroze, porphyria, chorea minor, thromboembolism, cholelithiasis, as well as diseases that are accompanied by disturbances circulatory , eg, diabetes . lupus . Crohn's disease . phlebitis . colitis and others.
Side effects Dimia
Side effects Dimia can be expressed in the following ailments from genitourinary, nervous, digestive and cardiovascular :
- vaginal bleeding spotting or breakthrough acyclic nature ;
- candidiasis ;
- breast tenderness;
- rarely, but it may occur hypertrophy breast, and change the composition of the secretion vagina ;
- increase or decrease libido ;
- headache ;
- migraine ;
- mood swings;
- extremely rare, but can occur arterial , and venous thrombosis ;
- nausea ;
- giperkalimiya ;
- insomnia ;
- diarrhea ;
- vomiting .
Everything else, while taking the drug may occur allergic reactions and expressed in itching, rashes on the skin, urticaria and erythema . It is worth remembering that if you use contraceptive , Including the preparation Dimia can increase body weight, as well as intolerance to contact lenses occur, develops chloasma (hyperpigmentation) .
Tablets Dimia, instructions for use (method and dosage)
To learn how to take the drug can be found in the instructions on Dimia. These contraceptives should not take every passing day. Doctors recommended to do this at the same time necessarily in that order, which is typically marked on the blister. K ontratseptivy Dimia as well, and other similar drugs have to be used continuously for 28 days.
New packaging birth control pills Dimia is opened only after the previous one. Around the third day from the start of receipt of the last of a number of tablets in a blister (the period of placebo) may begin neobilnye bleeding . If the package contraceptive not over by the end of the month, then re-start taking pills on the first day menses .
When sexual intercourse during the first seven days of use of the drug is necessary to apply additional methods contraception (barrier). In the transition to the use of other complex after Dimia contraceptives , eg, transdermal patch . tablets . vaginal rings and so on, should begin to take the drug once a day after using the previous method Contraception .
When you go to Dimia after use contraceptive Which contain exclusively progesterone ( injections, implants, mini-pill ) Or after IUD (spiral) to take the drug at any convenient day. However, prior to using the tablets should be used Barrier methods of contraception.
On prescription woman may start taking these pills a day after an interruption pregnancy (abortion, vacuum) . After delivery it is recommended to wait 28 days and then resume the drug. It is important to note that the missed reception placebo tablets (4-row blister) - is unimportant factor.
However, this rule does not apply to the tablet, containing in its composition the active substances ethinyl estradiol and drospirenone . If after the last administration of the tablet is not 12 hours have passed, the level of contraceptive protection is not reduced. Missed tablet should be taken as soon as possible, and the next - at the usual time.
Do not make tablet-free interval of more than 7 days, because it is the amount of time necessary for the suppression of hypothalamic-pituitary ovarian systems . To ensure proper use contraceptive should adhere to the following guidelines:
- when skipping taking the pill during the first week use of the drug is a woman, as soon as possible to resume the use of the contraceptive As well as to avoid the risk of getting pregnant be sure to use additional methods barrier contraception over the next seven days;
- if missed doses of 8 to 14 days of its use should be as soon as possible to resume the use of Dimia, and then return to the normal schedule, and the need for additional contraception is not, if in the previous seven days, a woman does not forget to take the pill;
- efficiency and reliability of the method Contraception significantly reduced in that case the admission of the drug occurred in the period from 15 to 24 days to use it, because at that time a woman needs to go to placebo tablets .
To avoid unnecessary pregnancy in case of the last of the situations described skip taking the drug, a woman should as quickly as possible to take a pill instead of missing. Next, it is necessary to stick to their normal dosing schedule until the end of active pills. As a result of the mixing chart reception contraceptive Calculated at 28 days, remain in the blister placebo tablets Who do not need to take.
Rather, in this embodiment, normal bleeding "undo" will not be until the end of the next pack contraceptive, however, can occur spotting . If you missed doses during the period from 15 to 24 days of the start of its use woman can not return to a normal schedule of Use contraceptives and take 4 days (including days missed) placebo tablets And then proceed to the new packaging.
If such an embodiment is not stepped bleeding "undo" It is necessary to consider the possibility of pregnancy. In the presence of gastrointestinal disorder efficacy is reduced because active connections will not be active until the end of the stomach sucked. If after 4 hours of taking birth control pills a woman vomited, should immediately take a second, ie, a replacement pill.
If not monthly when receiving Dimia, it may signal the occurrence of pregnancy . It should be noted that spotting "cancel" a woman can adjust, for example, to delay their own by changing the dosing schedule.
This can skip placebo tablets and immediately begin to receive tablets containing an active compound acting from a new package. It is noteworthy that the delay or shift bleeding "undo" may appear acyclic spotting or profuse bleeding .
Overdose
Currently, cases of overdose Dimia no information. However, based on experience with the use comprehensive contraceptive Such as this when the drug overdose can cause symptoms such as nausea, vaginal bleeding, and vomiting . If you experience these symptoms should stop using the product and seek medical advice.
Cooperation
To avoid weakening the effectiveness of contraceptives should not be used in conjunction with Dimia drugs that affect liver enzymes , eg, Topiramate, griseofulvin, primidone, phenytoin, oxcarbazepine, rifampicin, felbamate, barbiturates and others, as well as medicines containing St. John's wort its chemical composition.
On hepatic metabolism the drug may have a negative impact HIV protease inhibitors and non-nucleoside And combinations thereof. Lowering circulating estrogens , And hence the efficiency Dimia occurs while receiving Tetracycline and ampicillin .
For 28 days and 7 (respectively) after administration of drugs affecting induction of liver enzymes, and antibiotics should renounce the use of this drug. Contraceptives may affect the action of certain drugs, so before using Dimia should carefully read the instructions.
Terms of sale
It sold only on prescription.
Storage conditions
Contraceptives are stored out of the reach of children, at a temperature no higher than 25 C.
Shelf life
2 years.
Cautions
Constant use contraceptives may increase the risk of thromboembolism . And the risk is highest in the first year of contraceptive use. If the reception Dimia any symptoms listed below, you should immediately discontinue use of the drug:
- lower extremity edema and strong pain ;
- breathlessness ;
- sudden loss of sight ;
- cough ;
- causeless severe headache;
- diplopia ;
- vertigo ;
- aphasia ;
- speech disorder ;
- acute abdomen ;
- collapse ;
- numbness ;
- weakness ;
- movement disorders .
During the application of the risk of hazardous Dimia thromboembolic disorders essentially occurs when:
- genetic predisposition;
- after age 30;
- obesity ;
- immobilization and after emergency surgery;
- smoking;
- hypertension ;
- Atrial Fibrillation ;
- migraine ;
- dislipoproteinemia ;
- Diseases heart valves.
If you are using a contraceptive should definitely take into account the risk of thromboembolism particularly after delivery As well as the development of other adverse effects during diabetes, Crohn's disease, colitis, anemia and so on. Women are not worth much without the doctor's recommendations, as well as preliminary medical examination to start taking the drug.
It is important to be sure to exclude pregnancy . While contraceptive use may appear bleeding "cancel", so the assessment of normality excreta It can be carried out after three months (adjustment period) since the start of the use of birth control pills.
Analogs Dimia
Femoden
Jess
Jess Plus
Zoeli
Mersilon
Lindinet
Miniziston
Silest
Rigevidon
Yarina
Perhaps the most common structural analogues Dimia are the following similar chemical composition and mechanism of action of drugs:
- Jess;
- Midian;
- Dailla;
- Yasmin;
- Shimizu.
Dimia or Jess?
Often women can not choose between the two functions like birth control pills. The main difference Dimia and Jess can assume that the first product is a cheaper analog of the second.
During pregnancy and lactation
The drug may not be used during pregnancy . If conception has occurred when receiving Dimia should immediately stop taking contraceptives. It is worth noting that the contraceptive has a negative impact on the amount of milk and its composition. Therefore it is necessary to abandon the drug while breast-feeding.
Reviews Dimia
We can say that in general reviews about Dimia positive drug does its job and protect against unwanted pregnancy with proper and regular use of it. However, some women expressed negative about birth control, because they are faced with the side effects of the drug, for example, such as itching . weight gain . the occurrence of varicose veins.
It should be particularly noted that in many reviews on the pill Dimia women talk about positive cosmetic effect that the drug has on the skin. Doctors about this birth control good, though doctors also pay attention to women in the contra-indications and side effects of the drug, and another call before taking contraceptive undergo a medical examination.
Price Dimia where to buy
Although the price Dimia will differ depending on the region, the drug can be attributed to the group of budget and at the same time an effective contraceptive. The average price of contraceptive pills Dimia does not exceed 500 rubles.
No comments:
Post a Comment