Ultrakain

Description overdue on 08/25/2014

• Latin name: Ultracain
• ATC code: N01BB08
• Active substance: Articaine (Articaine)
• Manufacturer: Hoechst, Germany

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• Composition
• Product form
• Pharmacological action
• Pharmacodynamics and pharmacokinetics
• Indications
• Contraindications
• Side effects
• Instructions for use ultrakain (method and dosage)
• Overdose
• Cooperation
• Terms of sale
• Storage conditions
• Shelf life
• Cautions
• Analogs
• Babies
• With alcohol
• During pregnancy (and lactation)
• Reviews
• Price, where to buy

Composition

The preparation consists of the following active ingredients: Articaine hydrochloride   and adrenaline hydrochloride . Also in the formulation includes additional components: sodium chloride . sodium metabisulfite . treated water .

As part of articaine in the cartridge and ampoules no preservative, so the risk of allergic reactions   in patients is minimized.

Product form

Ultracain contained in ampoules   or in bottles   2 ml, the drug may also be packaged in the cartridge cylinder   1, 7 ml. Thanks to several packaging options may be carried out a variety of local anesthesia .

Articaine (INN: Articaine + Epinephrine) is available in three forms: Ultrakain D   (comprising no epinephrine / adrenaline) Ultrakain D-C Forte   (the concentration of epinephrine in the composition - 1: 100000), Ultrakain D-C   (the concentration of epinephrine in the 1: 200000).

Accordingly, the difference Ultrakain   and Ultrakain D-C And opposed Ultrakain   and Ultrakain Forte   - Concentration epinephrine .

Pharmacological action

Ultracain mestnoanesteziruyuschee has pharmacological effects. Under its influence there is a blocking membrane depolarization of nerve endings, which in turn, prevents irritation and conduct nerve impulses.

Influence of funds due to those components that are part of it.

Pharmacodynamics and pharmacokinetics

Tool takes effect immediately after its introduction is made. Period, which lasts for anesthesia is from 1 to 3 hours. It will be appreciated that in the acidic medium decreases efficiency exposure means.

The dental practice tool is widely used as a local anesthetic, if it is applied to minimize the risk of side effects. Articaine not suspend the regenerative processes, prevents high blood pressure.

Excreted urine excreted over 5 to 10 hours.

Indications

It shows the use of the drug for infiltration and conduction anesthesia during operations and interventions of a diagnostic nature, to relieve pain.

Articaine in Dentistry   assigned during various procedures, including the fillings and removing dental crowns during the installation process, for performing the preventive procedures treated wounds. It is also practiced in the administration   surgical interventions Carried in the nasopharynx.

Contraindications

To apply ultrakain defines the following contraindications:

• a high level of sensitivity;
• B12-deficiency anemia ;
• paroxysmal ventricular tachycardia   or atrial tachyarrhythmia ;
• carbohemia ;
• hypoxia ;
• closure glaucoma ;
• intolerance of the body sulfo (especially in people who are suffering asthma ).

Relative contraindications (use of funds with caution) are noted in the following cases:

• at cholinesterase deficiency ;
• at renal failure ;
• at diabetes ;
• at asthma ;
• at hyperthyroidism ;
• at anemia ;
• at hypertension .

Also used with caution in the treatment of children (not desirable to use the drug to children under 4 years of age), as well as for paratserebralnoy blockade .

Side effects

When using articaine may experience the following side effects:

• In functions CNS : headache , Impaired consciousness,   tremor , Respiratory failure, convulsions.
• In functions GI : vomiting . diarrhea . nausea .
• In functions senses : diplopia In rare cases - transient visual disturbances.
• In functions Cardiovascular : Decrease Blood Pressure . bradycardia .   tachycardia . arrhythmia .
• Allergic symptoms:   itchiness and redness of the skin, rhinitis . conjunctivitis , Edema.

When using articaine in dentistry, side effects may include: inflammation or swelling at the injection site, the development of ischemic zones in the place where the deposit of funds. When was broken machinery of administration, nerve damage may occur.

Those side effects related to the influence adrenaline   ( arrhythmia . tachycardia , Increased blood pressure), are rare, if the concentration of epinephrine in the preparation composition is relatively low (1: 200,000 and 1: 100,000).

Instructions for use ultrakain (method and dosage)

Instructions on Ultrakain provides that the drug is injected under the skin of 5-10 ml. But before applying to the patient is necessary to carry out the necessary diagnostic procedures. After the operation method was carried out, the patient is accurately controlled arterial pressure As well as his state of the central nervous system and respiratory system.

Instructions for use in ultrakain Dentistry provides that when filling or tooth extraction in the palatal suture is introduced for 1, 5 ml of the product. The highest dose for an adult should not be greater than 7 mg, children after the age of four is a dose of less than 5 mg of funds. After anesthesia for some time gradually restored the sensitivity of the oral cavity. Eating can be approximately 2-3 hours after anesthesia.

With infiltration anesthesia Articaine applied in the following doses: tonsillectomy each tonsil using 5-10 mL agents; reposition at fracture may be used from 5 to 20 ml articaine; when suture the perineum - 5-15 ml.

With conduction anesthesia   depending on the type of intervention may be administered from 1 to 30 ml agent.

Overdose

In overdose symptoms are the following: impaired consciousness or loss . changes in breathing Up until it stops, tremor . muscle twitching, convulsions . nausea and vomiting . a sharp drop in pressure . shock . cardiac arrest .

If you notice any of side effects   an urgent need to suspend injection , To transfer the patient to a horizontal position to provide him with maximum airway. It is important to closely monitor pulse   and arterial pressure .

Further treatment is carried out, depending on how serious the violation. The patient is given oxygen, carried out artificial respiration or made endotracheal intubation Whereby controlled ventilation.

Do not use drugs analeptic of the central action. If a person has marked muscle twitches occur or generalized convulsions, it was administered intravenously or ultrashort barbiturates short exposure. When blood flow disorders and manifestations of shock administered intravenously and plasma-electrolyte solutions, as well as glucocorticoids .

If there is increasing bradycardia, vascular collapse threatens the patient practiced intravenous 0, 25-1 ml of 0, 1 mg / ml of adrenaline. With tachycardia   used antiarrhythmic agents.

If people who are sick hypertension After application ultrakain blood pressure rises, you must apply peripheral vasodilators.

Cooperation

In an application tricyclic antidepressants , MAO inhibitors, there is a growing influence of hypertensive drug.

Upon receipt of vasoconstrictor drugs increase the effect mestnoanesteziruyuschee artikaina .

In simultaneous treatment nonselective beta-blockers   It increases the risk of manifestation bradycardia   and hypertensive crisis .

Under the influence articaine, the influence of other analgesics include, as a consequence, there is inhibition of the nervous system.

Terms of sale

The pharmacy articaine may be purchased by prescription.

Storage conditions

The tool should be stored at a temperature not exceeding 25 ° C. Articaine should be protected from children.

Shelf life

You can store 5 years

Cautions

It can not be administered by intravenous means. To avoid intravascular injection, it is necessary to hold Test aspiration . Injection pressure must meet the sensitivity of tissues.

Do not type drugs in the area of ​​inflammation.

Eating after dental procedures carried out with anesthetic articaine, only after fully recovered sensitivity.

To prevent infection, it is necessary each time the fence solution of vials used only new sterile needle and syringe. If the vial has been opened, it should be used strictly according to instructions and apply for two days.

Is it possible to drive trucks or work with the precise mechanism of the patient, who underwent anesthesia using articaine, the physician must determine.

Patients suffering asthma , The drug can cause acute attacks, respiratory failure.

Analogs

Match code ATC 4th level:

• Ultrakain D-C Forte
• Ultrakain D-C
• Articaine
• Emla
• Lidocaine

As active substances are analogues ultrakain funds Ubistezin Forte . Articaine . Artifrin . Primakain with adrenaline . Tsitokartin   and Septanest with adrenaline . Articaine with epinephrine .

By the same drug group includes drugs Likain . Marcaine . Lidocaine . Skandonest   and etc.

Is it better to articaine or lidocaine?

The drug Lidocaine is also used for anesthesia during dental procedures. It rarely causes allergic reactions, although it has a number of contraindications. However, articaine - less toxic agent which allows more stable anesthesia.

Babies

In childhood, used carefully, it is not recommended for use for children under 4 years.

With alcohol

Despite the fact that the instructions to the drug does not describe how the interaction of alcohol and articaine, before or after administration alcohol used is undesirable even in small doses.

Articaine in pregnancy and lactation

Articaine at pregnancy   desirable to apply in a form where it is noted the concentration of epinephrine 1: 200,000, since this concentration it does not penetrate through the placenta. Use this medication during the childbearing can only indications and under strict medical supervision.

With breastfeeding   articaine may fall in breast milk in low concentrations so lactation after anesthesia can not stop.

Reviews ultrakain

The forums ultrakain positive reviews, they noted the effectiveness of this tool as a strong analgesic. However, notes that initially it is important to find out whether a person intolerant of means to avoid the appearance of negative effects.

Price ultrakain where to buy

Price ultrakain depends on the shape of its release and variety means. Buy Ultrakain D-C   (10 vials) may be an average of 550 rubles. Price 1 ampoule Ultrakain D-C Forte   an average of 50 rubles. What is the cost of funds to other forms of packaging, can be found in a particular place of sale.

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