Description overdue on 01/09/2014
- Latin name: Reaferon-Lipint
- ATC code: L03AB05
- Active substance: Interferon alfa-2b
- Manufacturer: Vector-Medica JSC, Russia
- Composition
- Product form
- Pharmacological action
- Pharmacodynamics and pharmacokinetics
- Indications
- Contraindications
- Side effects
- Instructions for use (method and dosage)
- Overdose
- Cooperation
- Terms of sale
- Storage conditions
- Shelf life
- Cautions
- Analogs
- Babies
- With alcohol
- During pregnancy (and lactation)
- Reviews
- Price, where to buy
Composition
The composition of one capsule of the drug included interferon alfa-2b, recombinant human of 500,000 IU - the active substance.
Excipients:
- 8, 01 mg - sodium chloride;
- 4, 52 mg - hydrogen phosphate dodecahydrate sodium;
- 0, 56 mg - sodium dihydrogen phosphate dihydrate;
- 41, 18 mg - lipoid C 100;
- 4, 53 mg - cholesterol;
- 91, 34 mg - lactose monohydrate;
- 0, 56 mg - alpha-tocopherol acetate (vitamin E);
- 7, 54 mg - colloidal anhydrous silica.
The shell consists of:
- 2% - titanium dioxide (E 171) and 100% gelatin.
Product form
The medicament Lipint-IFN produced in the form of gelatin capsules fine crystalline powder according to 500,000 IU of active substance.
One package contains 10 capsules.
Pharmacological action
The antiviral and immunomodulatory.
Pharmacodynamics and pharmacokinetics
The antiviral effect of the drug IFN-Lipint related to the ability of its active substance - interferon alfa-2b actively involved in the process of viral reproduction at the cellular level. With the influence of specific receptors on the cell membrane, making intracellular changes, including the synthesis of specific enzymes ( protein and adenilatsintetazy ) And Cytokine Which, in turn, inhibits the formation of RNA and viral protein .
Immunomodulatory drug action manifests increased activity macrophages and "Kilernyh" cells changing the number and quality produced cytokines Improving the functionality of the action immunocompetent cells And modifying the production and secretion of intracellular proteins.
Indications
Treatment respiratory viral diseases and Flu Adult patients aged as part of a treatment as well as prevention of disease during ascent and during epidemics.
Contraindications
- the patient's age less than 18 years;
- period pregnancy and breastfeeding;
- intolerance lactose deficit lactase, glucose-galactose syndrome malabsorption;
- individual hypersensitivity to interferon or other components of the drug.
With extreme caution:
- severe myelosuppression;
- kidney and / or liver failure.
Side effects
During the application of IFN-Lipint capsules may manifest allergic reactions, as well as flu-like symptoms Comprising chills, fatigue, fever, fatigue, headache, arthralgia, myalgia, loss of appetite.
Instructions for use (method and dosage)
IFN-Lipint in capsule form is recommended for adult patients receiving and not suitable for children.
The medicament is intended for peroral (domestic) application 30 minutes before a meal.
The capsule is swallowed whole and recommend to drink water.
With difficulty swallowing drug-Reaferon Lipint, instruction on the application is subject to careful opening the capsule and receiving its contents with a small amount of water.
The daily dose of IFN-Lipint in capsules for the treatment of SARS and Flu of 1000000 IU (2 capsules of 500,000 IU per day). The drug is recommended to take in the morning and evening for 5 days.
Prevention SARS and Flu carried out at a dose of 500,000 IU (1 capsule), which is taken 2 times a week. The course of prophylactic use is 30 days.
Overdose
Cases of drug overdose IFN-Lipint observed. It is theoretically possible aggravation of dose-related side effects. Treatment - symptomatic.
Cooperation
Studies have shown the ability to Interferon reduce the activity P-450 cytochromes , Thereby affecting the metabolism Phenytoin, cimetidine, Dipyridamole diazepam, theophylline, warfarin, propranolol and some cytostatics.
IFN-Lipint can aggravate neurotoxic, cardiotoxic, myelotoxic effect last prescribed drugs or medication used simultaneously.
It is not necessary to assign IFN-Lipint conjunction with drugs that depress the central nervous system as well as immunosuppressive drugs (including oral and parenteral corticosteroids ).
Terms of sale
Over the counter.
Storage conditions
In the refrigerator at a temperature not exceeding 8 ° C.
Shelf life
2 years.
Cautions
If you experience allergic reactions while receiving IFN-Lipint should contact your doctor.
Analogs
Interferon
Nazoferon
Viferon
Infagel
IFN-EU-Lipint
IFN-EU
Altevir
Algeron
Genferon Light
Genferon
Grippferon
- Viferon;
- Genferon;
- Betaferon;
- Diaferon;
- Lokferon etc.
Babies
The capsules of the drug IFN-Lipint not apply for children.
With alcohol
Avoid drinking beverages containing alcohol during therapy.
During pregnancy and lactation
Not used during pregnancy and lactation.
Reviews of IFN-Lipinte
In the user forums drugs Interferon for the prophylaxis and treatment of SARS and Flu consistently receive positive feedback.
Recall that this drug due to lack of studies, is not intended for children. Reviews on Reaferon Lipint capsules, also called a mistake - "Reaferon lipid" in the treatment of pediatric patients should be viewed with skepticism.
Price Reaferon Lipint where to buy
Price Reaferon Lipint in the form of capsules 500,000 IU №10 varies from 508 to 755 rubles.
When searching for a preventive agent for children belonging to the same pharmacological subgroup with reaferon Lipint, it is better to buy a children's counterpart - IFN-EU-Lipint, available in powder form for suspension, which approximates the price - 500 rubles.
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